Search results for "CADA"
showing 10 items of 1418 documents
Assessment of normal patellar cartilage volume and thickness using MRI: an analysis of currently available pulse sequences.
1996
Objective. The objective of this study was to analyse the potential of magnetic resonance imaging for valid determination of patellar cartilage thickness, comparing currently available pulse sequences. Design. In six patients and one cadaver the cartilage was repetitively imaged employing three spin-echo and six three-dimensional gradient-echo sequences. In the cadaveric specimen the total volume and the regional distribution of cartilage thickness were assessed and compared with the values obtained from anatomical sections by image analysis. Results and conclusions. The FLASH and fat-suppressed FLASH sequences allowed the most accurate determination of the cartilage volume and thickness. F…
Determination of knee joint cartilage thickness using three-dimensional magnetic resonance chondro-crassometry (3D MR-CCM)
1996
The objective of this article was to analyze the accuracy and precision with which the quantitative distribution of articular cartilage can be determined in the knee joint using MRI. A three-dimensional (3D) technique that accounts for the out-of-plane deviation of the interface normal in strongly curved joint surfaces (3D MR-CCM) has been developed for cartilage thickness measurements. Eight cadaveric knee-joint specimens and six volunteers were imaged using a fat-suppressed gradient-echo sequence at a resolution of 2 x 0.31 x 0.31 mm3. Cartilage volumes and topographical thickness maps were obtained and compared with those derived from anatomical sections by image analysis. The deviation …
Non-invasive determination of cartilage thickness throughout joint surfaces using magnetic resonance imaging.
1997
Abstract Data on articular cartilage thickness in the living are important for the design of computer models, aimed at preoperatively assessing the effect of surgical procedures on joint contact and load transmission, and for the calculation of cartilage material properties from its deformational behavior as determined during arthroscopy. A non-invasive method for measuring cartilage thickness in living subjects is, however, not available. A technique based on magnetic resonance imaging has therefore been tested for assessing articular cartilage thickness throughout joint surfaces. The accuracy is determined by comparing cartilage thickness maps obtained from three patellar specimens with a…
Treatment of acute rejection of cadaveric renal allografts with rabbit antithymocyte globulin.
1982
In a prospective randomized single-blind trial, we compared the effectiveness of rabbit antithymocyte globulin (RATG) in the treatment of acute renal graft rejection with the results of treatment by high oral doses of prednisone. Twenty recipients of cadaveric kidneys were included in each group. In the RATG group, the prednisone dose was not increased and a dose-by-rosette protocol was used to keep T cell levels between 50 and 150/mm3. In this group 15 of the 20 patients responded to the treatment. One of these patients lost her kidney afterward because of a technical failure. In five patients rejection was irreversible despite a subsequent course of high-dose prednisone orally. In the pre…
Subtemporal Keyhole Approach to the Suprasellar and Petroclival Region: Microanatomic Considerations and Clinical Application
1997
OBJECTIVE: To minimize surgical invasiveness, the keyhole concept is applied to the subtemporal approach. METHODS: Anatomic features were studied in 14 sides of adult cadaver heads, and the technique was used in 162 interventions. Although most of the lesions treated were 3 cm in size or smaller, larger lesions were also treated using this technique. In some cases, if needed, an endoscope-assisted microsurgical technique was used. RESULTS: The cadaveric study provided intimate experience with the microsurgical anatomy of the approach. The 162 consecutive patients who were operated on harbored various types of lesions; the most recent 43 consecutive interventions were investigated in detail.…
From the Big Five to the General Factor of Personality: a Dynamic Approach
2014
AbstractAn integrating and dynamic model of personality that allows predicting the response of the basic factors of personality, such as the Big Five Factors (B5F) or the general factor of personality (GFP) to acute doses of drug is presented in this paper. Personality has a dynamic nature, i.e., as a consequence of a stimulus, the GFP dynamics as well as each one of the B5F of personality dynamics can be explained by the same model (a system of three coupled differential equations). From this invariance hypothesis, a partial differential equation, whose solution relates the GFP with each one of the B5F, is deduced. From this dynamic approach, a co-evolution of the GFP and each one of the B…
Digital assessment of MRI for lumbar disc desiccation. A comparison of digital versus subjective assessments and digital intensity profiles versus di…
1994
During magnetic resonance imaging, a vast amount of digital data on anatomic structures is translated into images, which are then assessed subjectively. The development of an objective, sensitive method to directly assess the digital data would have clear benefits, particularly for clinical research on disc degeneration. The study goals were to develop a method of digital assessment of disc desiccation and to compare digital signal intensity profiles with discographic patterns and macroanatomic findings. Proton density-weighted MRIs were obtained from 45 males (9-77 years) and digital analysis was done with a freely selectable region of interest facility. The adjacent cerebrospinal fluid (C…
Towards a unified analysis of cerebellum maturation and aging across the entire lifespan: A MRI analysis
2021
[EN] Previous literature about the structural characterization of the human cerebellum is related to the context of a specific pathology or focused in a restricted age range. In fact, studies about the cerebellum maturation across the lifespan are scarce and most of them considered the cerebellum as a whole without investigating each lobule. This lack of study can be explained by the lack of both accurate segmentation methods and data availability. Fortunately, during the last years, several cerebellum segmenta- tion methods have been developed and many databases comprising subjects of dif- ferent ages have been made publically available. This fact opens an opportunity window to obtain a mo…
Age slowing down in detection and visual discrimination under varying presentation times
2017
[EN] The reaction time has been described as a measure of perception, decision making, and other cognitive processes. The aim of this work is to examine agerelated changes in executive functions in terms of demand load under varying presentation times. Two tasks were employed where a signal detection and a discrimination task were performed by young and older university students. Furthermore, a characterization of the response time distribution by an exGaussian fit was carried out. The results indicated that the older participants were slower than the younger ones in signal detection and discrimination. Moreover, the differences between both processes for the older participants were higher,…
pBrain: A novel pipeline for Parkinson related brain structure segmentation
2020
[EN] Parkinson is a very prevalent neurodegenerative disease impacting the life of millions of people worldwide. Although its cause remains unknown, its functional and structural analysis is fundamental to advance in the search of a cure or symptomatic treatment. The automatic segmentation of deep brain structures related to Parkinson's disease could be beneficial for the follow up and treatment planning. Unfortunately, there is not broadly available segmentation software to automatically measure Parkinson related structures. In this paper, we present a novel pipeline to segment three deep brain structures related to Parkinson's disease (substantia nigra, subthalamic nucleus and red nucleus…