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showing 10 items of 2320 documents

Movements Execution in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease

2007

We evaluated the relationship between motor and neuropsychological deficits in subjects affected by amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer’s Disease (AD). Kinematics of goal-directed movement of aMCI and AD subjects were compared to those of age-matched control subjects. AD showed a slowing down of motor performance compared to aMCI and controls. No relationships were found between motor and cognitive performances in both AD and aMCI. Our results suggest that the different motor behaviour between AD and aMCI cannot be related to memory deficits, probably reflecting the initial degeneration of parietal-frontal circuits for movement planning. The onset of motor dysfunct…

Malemedicine.medical_specialtyMild Cognitive ImpairmentMotor dysfunctionneuropsychologyNeurosciences. Biological psychiatry. NeuropsychiatryDiseaseAudiologyNeuropsychological TestsMotor behaviourSeverity of Illness Indexbehavioral disciplines and activitiesAlzheimer Diseasemental disordersmedicineReaction TimeHumansBiomechanicsClinical NoteAlzheimer’s DiseaseCognitive impairmentalzheimer's disease mild cognitive impairment kinematicsAgedDemographypointingMovement DisordersNeuropsychologyCognitionGeneral MedicineControl subjectsBiomechanical PhenomenaSeverity of Illness Index; Humans; Alzheimer Disease; Aged; Mental Recall; Cognition Disorders; Demography; Movement Disorders; Neuropsychological Tests; Amnesia; Biomechanics; Female; Male; Reaction TimeNeuropsychology and Physiological PsychologyNeurologykinematicsMental RecallSettore MED/26 - NeurologiaFemaleNeurology (clinical)AmnesiaPsychologyCognition DisordersNeuroscienceMovement planningRC321-571Behavioural Neurology
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Rectal cancer threatening or affecting the prostatic plane: is partial prostatectomy oncologically adequate? Results of a multicentre retrospective s…

2015

Aim The management of rectal cancer threatening or affecting the prostatic plane is still under debate. The role of preoperative chemo radiotherapy and the extent of prostatectomy seem to be key points in the treatment of these tumours. The aim of the present study was to evaluate the pathological circumferential margin status and the local recurrence rate following different therapeutic options. Method A multicentre, retrospective study was conducted of patients with rectal cancer threatening or affecting the prostatic plane, but not the bladder, judged by magnetic resonance imaging (MRI). The use of preoperative chemoradiotherapy and the type of urologic resection were correlated with the…

Malemedicine.medical_specialtyNeoplasm ResidualUrinary Fistulapreoperative radiotherapyColorectal cancermedicine.medical_treatmentUrethraProstateUrinary Fistulalocally advancedmedicineHumansNeoplasm InvasivenessRectal cancerPathologicalAgedRetrospective StudiesProstatectomymultivisceral resectionprostatemedicine.diagnostic_testRectal NeoplasmsProstatectomybusiness.industrypartial prostatectomyProstateGastroenterologyMagnetic resonance imagingRetrospective cohort studyChemoradiotherapy AdjuvantMiddle Agedmedicine.diseaseMagnetic Resonance ImagingNeoadjuvant TherapySurgerymedicine.anatomical_structureRadiotherapy AdjuvantNeoplasm Recurrence LocalbusinessChemoradiotherapyColorectal Disease
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Morphological analysis of the skeletal development in lateral cephalometric radiographs of HIV infected children ongoing Highly Active Antiretroviral…

2018

Background To investigate the skeletal development of HIV infected children through a morphological analysis of the cervical vertebrae (CV) in lateral cephalometric radiographs. Material and Methods The sample consisted of 86 lateral cephalometric radiographs of male and female children aged between 6 and 14 years old. The radiographs were equally distributed in groups 1 (HIV infected children) and 2 (non-infected children, paired by sex and age). Two examiners analyzed the CV according to the method of Hassel and Farman (1995). Spearman correlation coefficient was used to associate age and skeletal development within groups, while Mann-Whitney test compared the skeletal development between…

Malemedicine.medical_specialtyORTHODONTIC PROCEDURESAdolescentCephalometryRadiographyDentistryHIV Infections03 medical and health sciences0302 clinical medicineAntiretroviral Therapy Highly ActiveHiv infectedmedicineHumans030212 general & internal medicineChildGeneral DentistryBone Developmentbusiness.industryResearch030206 dentistryCraniometryMedically compromised patients in Dentistry:CIENCIAS MÉDICAS [UNESCO]Antiretroviral therapyRadiographymedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASOrthopedic surgeryMorphological analysisCervical VertebraeFemaleSurgerybusinessCervical vertebraeMedicina Oral Patología Oral y Cirugia Bucal
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Prevalence of apical periodontitis and frequency of root canal treatments in liver transplant candidates

2013

Aim: The purpose of this study was to investigate the prevalence of apical periodontitis (AP) and endodontic treatment in liver transplant candidates and control healthy subjects. Material and Methods: A descriptive cross-sectional study. Forty two liver transplant candidates (LTC) (study group) and 42 control subjects. Digital panoramic radiographs where used. Periapical status was scored according to the periapical index (PAI). Results were analysed statistically using the Chi-squared test and logistic regression. Results: Radiographic signs of AP in one or more teeth was found in 79% of patients in the study group and in 50% of control subjects (p = 0.008; OR = 3.7; C. I. 95% = 1.4 - 9.5…

Malemedicine.medical_specialtyOral healthRoot-canal treatmentCross-sectional studyRoot canalmedicine.medical_treatmentDentistryOdontologíaLiver transplantationLogistic regressionEndodonticsLiver diseaseApical periodontitisPrevalencemedicineHumansGeneral DentistryPeriodontitisPeriapical periodontitisbusiness.industryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in Dentistrymedicine.diseaseEndodonticsCiencias de la saludLiver TransplantationRoot Canal TherapyCross-Sectional Studiesmedicine.anatomical_structureHepatic cirrhosisOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASResearch-ArticleFemaleSurgerybusinessLiver diseasePeriapical PeriodontitisMedicina Oral Patología Oral y Cirugia Bucal
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Use of the universal pain assessment tool for evaluating pain associated with TMD in youngsters with an intellectual disability

2016

Background The Universal Pain Assessment Tool (UPAT) was used to assess the level of pain in people with limited communication skills. The UPAT enables clinicians to consult a specialized pain management team more often and lead to earlier interventions. The purpose of this study was to determine, whether the UPAT could be used as an extra tool to collect data on functional TMJ pain and to assess orofacial pain levels related to temporomandibular disorder(s) (TMD) in people with intellectual disabilities (ID). Material and Methods Non-down syndrome ID Athletes were screened during the Special Olympics European games in 2014. The clinical scores of possible functional jaw pain were collected…

Malemedicine.medical_specialtyOrofacial painAdolescentPsychological interventionMEDLINEResearch Diagnostic Criteria03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationPain assessmentFacial PainIntellectual DisabilityIntellectual disabilityMedicineHumansYoung adultGeneral DentistryPain Measurementbiologybusiness.industryAthletesResearch030206 dentistryTemporomandibular Joint Disordersmedicine.diseasebiology.organism_classificationMedically compromised patients in Dentistry:CIENCIAS MÉDICAS [UNESCO]stomatognathic diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASPhysical therapySurgeryFemalemedicine.symptombusiness030217 neurology & neurosurgery
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CSF APPsα and Phosphorylated Tau Protein Levels in Mild Cognitive Impairment and Dementia of Alzheimer's Type

2008

We exploratively measured APPs alpha, a secreted fragment of the non-amyloidogenic cleavage of amyloid precursor protein via a-secretase, and tau protein phosphorylated at threonine 181 (p tau) in the cerebrospinal fluid of 10 patients with mild cognitive impairment, 20 patients with dementia of Alzheimer's type, and 10 controls. Cerebrospinal fluid APPs alpha and p tau levels were correlated with cognitive performance. P tau levels were significantly elevated in mild cognitive impairment and in patients with dementia of Alzheimer's type, APPs alpha levels were significantly reduced in patients with dementia of Alzheimer's type compared to the controls. APPs alpha levels were associated wit…

Malemedicine.medical_specialtyPathologyTau proteintau ProteinsNeuropsychological TestsSeverity of Illness IndexCerebrospinal fluidDegenerative diseaseAlzheimer DiseaseInternal medicineTask Performance and AnalysismedicineAmyloid precursor proteinHumansDementiaSex DistributionThreonineAgedAnalysis of VariancebiologyChemistrymedicine.diseasePsychiatry and Mental healthMemory Short-TermEndocrinologyMental Recallbiology.proteinPhosphorylationFemaleNeurology (clinical)Amyloid Precursor Protein SecretasesGeriatrics and GerontologyAlzheimer's diseaseCognition DisordersBiomarkersJournal of Geriatric Psychiatry and Neurology
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Frequency of somatic symptoms in the general population: Normative values for the Patient Health Questionnaire-15 (PHQ-15).

2017

The PHQ-15 is widely used as an open access screening instrument for somatic symptoms in different health care settings. The objectives of the study were to contribute to the construct validity and to generate normative data for the PHQ-15.The survey was conducted in the general population in Germany from August 2011 to November 2014 (n=9250). All participants underwent an extensive core assessment including a set of questionnaires.Men reported significantly less (p0.001) physical symptoms than women (4.6 [SD=3.6] vs. 6.3 [SD=4.1]). The PHQ-15 total score was strongly correlated with the physical component of quality of life (r=-0.58), fatigue (r=0.56), anxiety (r=0.54) and sleep problems (…

Malemedicine.medical_specialtyPopulationAnxietyPatient Health Questionnaire03 medical and health sciences0302 clinical medicineQuality of life (healthcare)medicineHumans030212 general & internal medicineeducationPsychiatryDisease burdenFatigueeducation.field_of_studyConstruct validityReproducibility of ResultsMiddle AgedPatient Health QuestionnairePsychiatry and Mental healthClinical PsychologyMedically Unexplained SymptomsQuality of LifeNormativeAnxietyFemalemedicine.symptomPsychologyPsychosocial030217 neurology & neurosurgeryJournal of psychosomatic research
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Psychometric Analysis of the Selective Reminding Procedure in a Sample from the General Elderly Population

2000

The selective reminding procedure (SRP) has been proposed for the assessment of distinct aspects of episodic memory, i.e. storage to and retrieval from short-term and long-term memory, item learning and list learning, and as dementia screening tool. In the present study SRP results were analysed in 256 probands from the general elderly population. SRP scores were highly intercorrelated, and principal component analysis yielded only one single factor. The SRP scores were moderately and not differentially correlated with immediate and delayed free recall and recognition and with verbal fluency. All SRP scores discriminated nondemented probands with episodic long-term memory impairment from th…

Malemedicine.medical_specialtyPsychometricsCognitive NeuroscienceAudiologyenvironment and public healthDevelopmental psychologyMemorymedicineHumansMemory impairmentSemantic memoryVerbal fluency testEpisodic memoryAgedAged 80 and overPsychiatric Status Rating ScalesMemory DisordersWorking memoryMemoriaReproducibility of ResultsCognitionPsychiatry and Mental healthFree recallDementiaFemaleGeriatrics and GerontologyFactor Analysis StatisticalPsychologyDementia and Geriatric Cognitive Disorders
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Intact cross-modality text-specific repetition priming in patients with Alzheimer’s disease

2001

This study was aimed at investigating the basic mechanisms of the normal repetition priming evoked by text re-reading procedures in Alzheimer's disease (AD) patients (Monti, Gabrieli, Wilson, & Reminger, 1994; Monti et al., 1997). For this purpose, we contrasted the reading facilitation elicited by previous reading or listening to a text in a sample of AD patients and a group of age-matched normal controls. Consistent with previous evidence in normal undergraduates (Levy & Kirsner, 1989), previous listening to a text decreased the successive reading time of the same text (cross-modality priming). However, the reading facilitation elicited by previous reading of the same text (within…

Malemedicine.medical_specialtyRepetition primingRecognition (Psychology)AudiologyCueDevelopmental psychologyDegenerative diseaseStimulus modalityText miningAlzheimer Diseaseotorhinolaryngologic diseasesmedicineHumansReading; Recognition (Psychology); Humans; Alzheimer Disease; Practice (Psychology); Case-Control Studies; Cues; Aged; Mental Recall; Retention (Psychology); Male; FemaleActive listeningAgedSettore M-PSI/02 - Psicobiologia E Psicologia Fisiologicabusiness.industryRetention PsychologyRecognition PsychologyCognitionmedicine.diseaseClinical PsychologyReadingNeurologyPractice PsychologicalPractice (Psychology)Case-Control StudiesMental RecallFacilitationRetention (Psychology)FemaleSettore MED/26 - NeurologiaNeurology (clinical)CuesCase-Control StudiePsychologybusinessPriming (psychology)Human
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Xerostomia, thirst, sodium gradient and inter-dialytic weight gain in hemodialysis diabetic vs. non-diabetic patients

2017

Background In hemodialysis (HD) patients, xerostomia and hyposalivation may intensify sensations of thirst, and contribute to the intake of fluids and excessive inter-dialytic weight gain (IWG). Since IWG is regarded to be higher in diabetic patients than in non-diabetics HD enhancing their mortality, it is crucial to define plausible underlying causes. Therefore, the study investigates factors contributing to the increased IWG in diabetic HD patients. Material and Methods The study included 97 HD patients (38 diabetics) receiving hemodialysis. All participants completed surveys comprising the Dialysis Thirst Inventory (DTI) and Xerostomia Inventory. Unstimulated whole saliva flow rate (USW…

Malemedicine.medical_specialtySalivaSodiummedicine.medical_treatment030232 urology & nephrologychemistry.chemical_elementWeight GainGastroenterologyXerostomiaThirst03 medical and health sciences0302 clinical medicineRenal DialysisInternal medicineDiabetes mellitusMedicineHumansDiabetic NephropathiesGeneral DentistryDialysisbusiness.industryResearchSodium030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseMedically compromised patients in DentistryOtorhinolaryngologychemistryConcomitantUNESCO::CIENCIAS MÉDICASKidney Failure ChronicSurgeryFemaleHemodialysismedicine.symptombusinessWeight gainThirst
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