Search results for "CANDIDA"
showing 10 items of 844 documents
Nymphaeetum candidae Miljan 1933 in Poland
2011
This paper presents the distribution, floristic composition and ecological requirements of the water plant community <em>Nymphaeetum candidae</em> Miljan 1933, belonging to the <em>Potametea</em> class. Until present this community has been reported only from north-eastern Poland. During present studies it was stated also in the south-western part of the country. <em>Nymphaeetum candidae</em> is considered to be a rare and endangered plant community in several countries of Central Europe.
CANDIDA SEPTIC THROMBOSIS OF THE LEFT ATRIUM IN TWINS: REPORT OF TWO CASES
2009
Background: Preterms are often exposed to nosocomial infections in NICU. Candida infections are particularly common and can result in progressive organization of intracardiac thrombosis, usually in the right atrium. Design and population: GB (24.4 wg, 460 g, bigeminal pregnancy): he was affected by RDS, PDA, jaundice, anaemia and had been submitted to TPN with CVC, also because of anus imperforate. On the 50th day, haemoculture resulted positive for Candida parapsilosis and, by echocardiography, hyperecogen peduncolate formation in the appendix of left auricola. Despite antifungal therapy, exitus occurred. CM (32.4 wg, 1390 g, bigeminal pregnancy): on 2nd day, she was operated for “apple-pe…
Candida Albicans congenital infection in a preterm newborn
1997
Intrauterine infections may be due to a variety of pathogens other than the TORCH groups ones. Although Candida Albicans is frequently isolated within the urogenital tract of pregnant women, the fetal infection is rarely reported. We now report on a 26 weeks preterm baby in whom a Candida infection was diagnosed at birth in relation to gravidic anamnesis and typical micotic manifestations upon the placenta and the umbilical cord. Intensive cares and pharmacological treatment induced a progressive improvement of the clinical course and normalization of the laboratory parameters.
Proces selekcji kandydatów partii politycznych w wyborach Prezydenta RP – motywacje, dylematy, strategie
2022
Wybory prezydenckie pomimo dużego stopnia spersonalizowania, stanowią ważną przestrzeń rywalizacji międzypartyjnej. Doświadczenia polskich elekcji prezydenckich pokazują, że są one zdominowane przez kandydatów partyjnych. Podstawowym celem niniejszego artykułu, jest ukazanie procesu selekcji kandydatów partii politycznych na urząd Prezydenta RP, jako jednego z kontekstów wyborów prezydenckich w Polsce. Istotnym punktem rozważań jest odniesienie wskazanego procesu do aktywności przywódców partyjnych w tym zakresie, a dokładnie zauważalnej tendencji do rezygnacji z kandydowania. Trend ten wiąże się z wykorzystywaniem przez partie polityczne tzw. surogatów, czyli kandydatów zastępczych. Porusz…
Novel CREB3L3 Nonsense Mutation in a Family With Dominant Hypertriglyceridemia.
2015
Objective— Cyclic AMP responsive element–binding protein 3–like 3 ( CREB3L3 ) is a novel candidate gene for dominant hypertriglyceridemia. To date, only 4 kindred with dominant hypertriglyceridemia have been found to be carriers of 2 nonsense mutations in CREB3L3 gene (245fs and W46X). We investigated a family in which hypertriglyceridemia displayed an autosomal dominant pattern of inheritance. Approach and Results— The proband was a 49-year-old woman with high plasma triglycerides (≤1300 mg/dL; 14.68 mmol/L). Her father had a history of moderate hypertriglyceridemia, and her 51-year-old brother had triglycerides levels as high as 1600 mg/dL (18.06 mmol/L). To identify the causal mutation …
The Closed/Open Model for Lipase Activation. Addressing Intermediate Active Forms of Fungal Enzymes by Trapping of Conformers in Water-Restricted Env…
2001
The behavior of prototypic fungal lipases in a water-restricted environment has been investigated by exploiting the reported experimental strategy that allows the trapping (freeze-drying) of the enzyme in the conformation present in aqueous solution and to subsequently assay it in nonaqueous media [Mingarro, I., Abad, C., and Braco, L. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 3308-3312]. We now report, using simple esterification as well as acidolysis (triglycerides as substrates) as nonaqueous model reactions, that the presence of a detergent (n-octyl-beta-glucopyranoside) in the freeze-drying buffer, at concentrations below the critical micellar concentration, generates different catalyti…
Complementation of Saccharomyces cerevisiae mutationsin genes involved in translation and protein folding (EFB1 and SSB1)with Candida albicans cloned…
2000
We have demonstrated that the expression of Candida albicans genes involved in translation and protein folding (EFB1 and SSB1) complements the phenotype of Saccharomyces cerevisiae mutants. The elongation factor 1beta (EF-1beta) is essential for growth and efb1 S. cerevisiae null mutant cells are not viable; however, viable haploid cells, carrying the disrupted chromosomal allele of the S. cerevisiae EFB1 gene and pEFB1, were isolated upon sporulation of a diploid strain which was heterozygous at the EFB1 locus and transformed with pEFB1 (a pEMBLYe23 derivative plasmid containing an 8-kb DNA fragment from the C. albicans genome which contains the EFB1 gene). This indicates that the C. albic…
CandidaDB: a genome database for Candida albicans pathogenomics.
2004
CandidaDB is accessible at http://genolist.pasteur.fr/CandidaDB.; International audience; CandidaDB is a database dedicated to the genome of the most prevalent systemic fungal pathogen of humans, Candida albicans. CandidaDB is based on an annotation of the Stanford Genome Technology Center C.albicans genome sequence data by the European Galar Fungail Consortium. CandidaDB Release 2.0 (June 2004) contains information pertaining to Assembly 19 of the genome of C.albicans strain SC5314. The current release contains 6244 annotated entries corresponding to 130 tRNA genes and 5917 protein-coding genes. For these, it provides tentative functional assignments along with numerous pre-run analyses th…
Global transcriptional profiling ofCandida albicans cwt1 null mutant
2007
CaCwt1p is a Candida albicans putative transcriptional factor homologue to Rds2p in Saccharomyces cerevisiae. The lack of this protein in S. cerevisiae leads to a pleiotropic resistance to drugs and defects in cell wall architecture that are also detectable in C. albicans. It is also known that CaCwt1p is mainly expressed in the stationary growth phase of this fungus. In order to elucidate the role of CWT1, transcriptome analysis of the mutant strain was performed in exponential and stationary growth phases. A total of 460 genes were found to be up- or downregulated in the mutant strain growing exponentially, and 666 genes presented a misregulation when cwt1 cells reached the stationary pha…
A proteomic-based approach for the identification ofCandida albicans protein components present in a subunit vaccine that protects against disseminat…
2006
Candidiasis has become a prevalent infection in different types of immunocompromised patients. The cell wall of Candida albicans plays important functions during the host-fungus interactions. Cell wall (surface) proteins of C. albicans are major elicitors of host immune responses during candidiasis, and represent candidates for vaccine development. Groups of mice were vaccinated subcutaneously with a beta-mercaptoethanol (beta-ME) extract from C. albicans containing cell wall proteins. Vaccinated mice were then infected with a lethal dose of C. albicans. Increased survival and decreased fungal burden were observed in vaccinated mice as compared to a control group, and 75% of vaccinated mice…