Search results for "CANDIDA"

Pedigree verification with multiple candidate parents using Pedverif software

2010

Species like sheep and beef cattle are commonly raised in large herds and often on pasture with multiple sires joining the females for unrecorded natural insemination. This leads to offspring with multiple candidate parents and therefore uncertain parentage. Twins or triplets can be from multiple sires as well. Pedigrees from such populations are often problematic and need proper verification. The Pedverif computer program is able to verify normal pedigrees as well as pedigrees with multiple candidate parents.

Millimeter wave effects in Candida albicans cells

1985

Patogenicidad de la infección invasiva por Candida auris: virulencia en un modelo de infección in vivo y factores de riesgo de candidemia

2022

Candida auris es un hongo multirresistente que, desde su descripción por primera vez en el año 2009, se ha convertido en una grave amenaza mundial debido a su multirresistencia y su capacidad para causar brotes nosocomiales e infecciones invasivas con alta transmisibilidad y mortalidad. Sin embargo, la evidencia sobre su grado de patogenicidad en comparación con otras especies de Candida, sobre los factores de riesgo de enfermedad invasiva, así como sobre las complejas interacciones patógeno-huésped aún es limitada. En la presente Tesis Doctoral se ha analizado la patogenicidad de la infección por C. auris estudiando también su comportamiento in vivo y las relaciones patógeno-huésped en un …

Possible Roles of Mannoproteins in the Construction of Candida Albicans Cell Wall

1993

The shape of Candida albicans cells depends on their cell walls and some of their mannoproteins may act as modulators of the final molecular architecture. If that were the case, the wall mannoproteins might form part of what could be called a “morphogenetic code”.

Relationships Between Dimorphism, Cell Wall Structure, and Surface Activities in Candida albicans

1991

Most cells are covered with a complex network of interacting molecules that form the extracellular matrix. These molecules (proteins and polysaccharides) are secreted locally and interact among themselves to form an organized structure outside the cell plasma membrane. In unicellular eukaryotic organisms and plant cells, this structure is reinforced to withstand osmotic changes in the external environment, giving rise to the so-called cell wall.

Synthesis of Oxetane-Functional Aliphatic Polyesters via Enzymatic Polycondensation

2012

Synthesis, characterization, and thermal properties of a series of oxetane-functional aliphatic polyesters are investigated. The incorporation of the acid-sensitive 3,3-bis(hydroxymethyl)oxetane (BHMO) into polymers is achieved by using the enzyme CALB (Candida antarctica Lipase B) as a catalyst. This mild synthetic strategy provides well-defined, oxetane-functional polyesters. The enzymatic polycondensation allows for the synthesis of a series of aliphatic polyesters containing various ratios of the difunctional monomers sebacic acid, 1,8-octanediol, and BHMO with molecular weights between 5000–9800 g mol−1 and polydispersity indices (Mw/Mn) in the range of 1.25 and 1.92. Furthermore, cros…

Synthesis and Assembly of Wall Polymers on Regenerating Yeast Protoplasts

1983

Accumulation of chitin and glucan on S. cerevisiae and C. albicans protoplasts begins shortly after resuspension in the regeneration medium, and mannoprotein molecules also appear retained by the regenerating wall after 30–60 minutes in S. cerevisiae or after a longer lag period in C. albicans. Nevertheless, a considerable fraction of the synthesized mannoproteins, which in SDS-acrylamide gels exhibit a different pattern from that of wall mannoproteins of cells, are still released to the growth medium during at least eight hours. De novo synthesis of chitin synthase, but not of glucan synthase, is observed in S. cerevisiae from about 30 minutes after initiation of the regeneration process. …

Wall mannoproteins of the yeast and mycelial cells of Candida albicans: nature of the glycosidic bonds and polydispersity of their mannan moieties.

1988

SUMMARY: Zymolyase released between 20 and 25% of the total protein from purified walls of yeast (Y) and mycelial (M) cells of Candida albicans. The material released contained 92% carbohydrate (86% mannose and 6% glucose) and 7:< protein. Over 85% of the carbohydrate was N-glycosidically linked to the protein and the rest (less than 15%) was linked O-glycosidically. Highly polydisperse, high molecular mass mannoproteins, resolved by electrophoresis as four defined bands in Y cells and two bands in M cells, had both types of sugar chains. A 34 kDa species found in both types of cells had a single 2.5 kDa N-glycosidically linked sugar chain and a 3 1.5 kDa protein moiety. Polydispersity in t…

Structural mannoproteins released by β-elimination fromCandida albicanscell walls

1994

Abstract Mild alkaline solutions (β-elimination), after removing the non-covalently bonded wall materials by hot SDS, released 13% and 26% of remaining wall proteins from mycelial and yeast cells of Candida albicans, respectively. When the β-elimination was carried out after digestion of the walls with chitinase, four-fold more proteinaceous materials were released from mycelium and a similar amount in yeast walls. The solubilized materials were shown to be highly polydisperse, and endo-glycosidase H reduced their polydispersity and molecular masses, revealing different electrophoretic patterns in yeast and mycelial cell walls. The solubilized mycelial proteins carried N-glycosidic sugar ch…

Production of Dicarboxylic Acids and Flagrances by Yarrowia lipolytica

2013

Yeasts are excellent biocatalysts in the field of alkane and fatty acids transformation into dicarboxylic acids and lactones. Their ability to produce some diacids through simple, less expensive and more environment friendly routes than chemical pathways and to produce particular diacids (e.g. unsaturated ones) but also to transform natural substrates into lactones with a natural label has made them the subject of many researches. Although Candida species were often first studied, the development of genetic tools, the knowledge of the genome and some genomic and biotechnological particularities of Yarrowia lipolytica resulted to interesting developments with this species. This chapter aims …