Search results for "CAPE"

Public provision versus private provision of industrial land: a hedonic approach

2005

Abstract This study examines the factors that explain the differences observed between the industrial land prices offered by the public sector and those offered by the private sector by means of estimating three hedonic pricing models. The results obtained show that location, defined as the distance to a highway, the distance to the city business district and the distance to the capital of the province, have an important impact on industrial land value. However, this impact is greater when private developers provide the land. Other variables considered, such as who is behind the provision of the industrial land, have an important impact on sale prices.

Perceptions of Cultural Ecosystem Services: spatial differences in urban and rural areas of Kokemäenjoki, Finland

2021

This study aims to identify and evaluate the spatial distribution of Cultural Ecosystem Services (CES) benefits perceived by people in both urban and rural areas. A public participation GIS (PPGIS)...

IL PROGETTO CONTEMPORANEO DEGLI SPAZI PUBBLICI AD ALCAMO

2021

Il saggio presenta alcuni progetti significativi nella città di Alcamo, in cui il tema dello spazio pubblico si presenta come una sorta di allestimento, che configura luoghi di qualità per la città contemporanea. Questi interventi manifestano la loro partecipazione a quello spirito contemporaneo che elabora l’architettura come sistema di relazioni spaziali e temporali: ricostruendo un ordine tra le cose – i pieni ed i vuoti, la vegetazione e le pietre, la città e il paesaggio – e un legame evidente tra contemporaneità e tradizione.

Weekly docetaxel vs. docetaxel-based combination chemotherapy as second-line treatment of advanced non-small-cell lung cancer patients

2009

Abstract Background Doublet chemotherapy is more effective than single-agent as first line treatment of advanced non-small-cell lung cancer (NSCLC). No reliable information instead is available on the effect of doublets in second line treatment. The aim of DISTAL-2 study was to compare two doublets containing docetaxel with single agent docetaxel as second line treatment of patients with NSCLC (ClinicalTrials.gov id.:. NCT00345059 ). Methods NSCLC patients, aged 2 on days 1, 8, 15 q 4 weeks); arm B, weekly docetaxel (30 mg/m 2 on days 1, 8, 15) plus gemcitabine (800 mg/m 2 on days 1, 8 q 4 weeks) or plus vinorelbine (20 mg/m 2 on days 1, 8 q 4 weeks) depending on which of the two had been u…

Ģeogrāfija. Ģeoloģija. Vides zinātne: referātu tēzes

2011

Shedding Light on the Dark Ages: Sketching Potential Trade Relationships in Early Medieval Romania through Mitochondrial DNA Analysis of Sheep Remains

2021

Southeast Europe has played an important role in shaping the genetic diversity of sheep due to its proximity to the Danubian route of transport from the Near East into Europe, as well as its possible role as a post-domestication migration network and long tradition of sheep breeding. The history of Romania and, in particular, the historical province of Dobruja, located on the shore of the Black Sea, has been influenced by its geographical position at the intersection between the great powers of the Near East and mainland Europe, with the Middle Ages being an especially animated time in terms of trade, migration, and conflict. In this study, we analyzed the mitochondrial control region of fi…

Mechanical unfolding pathway of a model β-peptide foldamer.

2015

Foldamers constructed from oligomers of β-peptides form stable secondary helix structures already for small chain lengths, which makes them ideal candidates for the investigation of the (un)folding of polypeptides. Here, the results of molecular simulations of the mechanical unfolding of a β-heptapeptide in methanol solvent revealing the detailed unfolding pathway are reported. The unfolding process is shown to proceed via a stable intermediate even for such a small system. This result is arrived at performing non-equilibrium force ramp simulations employing different pulling velocities and also using standard calculations of the potential of mean force, i.e., the free energy as a function …

Single-molecule FRET studies of counterion effects on the free energy landscape of human mitochondrial lysine tRNA.

2011

The folding energy landscape of RNA is greatly affected by interactions between the RNA and counterions that neutralize the backbone negative charges and may also participate in tertiary contacts. Valence, size, coordination number, and electron shell structure can all contribute to the energetic stabilization of specific RNA conformations. Using single-molecule fluorescence resonance energy transfer (smFRET), we have examined the folding properties of the RNA transcript of human mitochondrial tRNA(Lys), which possesses two different folded states in addition to the unfolded one under conditions of thermodynamic equilibrium. We have quantitatively analyzed the degree of RNA tertiary structu…

Solvent-induced free energy landscape and solute-solvent dynamic coupling in a multielement solute

1999

AbstractMolecular dynamics simulations using a simple multielement model solute with internal degrees of freedom and accounting for solvent-induced interactions to all orders in explicit water are reported. The potential energy landscape of the solute is flat in vacuo. However, the sole untruncated solvent-induced interactions between apolar (hydrophobic) and charged elements generate a rich landscape of potential of mean force exhibiting typical features of protein landscapes. Despite the simplicity of our solute, the depth of minima in this landscape is not far in size from free energies that stabilize protein conformations. Dynamical coupling between configurational switching of the syst…

Plio-Quaternary coastal landscape evolution of north-western Sicily (Italy)

2023

We present and discuss the results of a geomorphological and geological study aimed at reconstructing the Plio-Quaternary evolution of the NW Sicily coastal belt, a low strain rate region in the central Mediterranean Sea. We performed morphometric and field analysis of Quaternary marine terraces extracting more than 300 shoreline location points subdivided into six orders. The obtained dataset was validate by investigating the morphological changes along topographic profiles and comparing the extracted locations and elevations with the stratigraphic boundaries in the Plio-Quaternary units. We distinguished two contiguous coastal sectors characterized by different paleo-shoreline elevations …