Search results for "CAPE"
showing 10 items of 1938 documents
Artificial increase of uracilemia during fluoropyrimidine treatment can lead to DPD deficiency misinterpretation
2021
Each year in France, >75 000 patients receive fluoropyrimidines, including 5-fluorouracil (5-FU) and its oral prodrug capecitabine (Xeloda), to treat digestive, breast and head and neck cancers.1 Among them, ∼20% will experience severe hematological and digestive toxicities and <2% will have a fatal outcome in the first two cycles. A part of these toxicities may result from a deficiency in dihydropyrimidine dehydrogenase (DPD) which catabolizes the endogenous uracil (U) into dihydrouracil (UH2) as well as 5-FU. In 2018, French Health Authorities [Haute Autorité de Santé (HAS) and Institut National du Cancer, (INCa)] recommended the evaluation of the enzymatic activity of DPD by measuring th…
On the listing and random generation of hybrid binary trees
1994
We consider in this paper binary trees whose internal nodes are either associative or non-associative. Hybrid binary trees are equivalence classes with respect to the associative property. We count, list and generate randomly hybrid binary trees using Fibonacci numbers.
Generation of Valid Labeled Binary Trees
2003
International audience; Generating binary trees is a well-known problem. In this paper, we add some constraints to leaves of these trees. Such trees are used in the morphing of polygons, where a polygon P is represented by a binary tree T and each angle of P is a weight on a leaf of T. In the following, we give two algorithms to generate all binary trees, without repetitions, having the same weight distribution to their leaves and representing all parallel polygons to P.
Linguistic Landscape geht digital: „Virtuelle sprachliche Landschaften“ auf Instagram am Beispiel der Weinstraßen in zwei mehrsprachigen Regionen (El…
2021
International audience; Kontext Die heutige Digitalisierung der Kommunikation wirft ein neues Licht auf traditionelle LL-Praktiken und -Problemstellungen (Androutsopoulos 2014). In Anschluss an Ivkovic & Lotherington (2009) und auf der Pilotstudie von Hiipala et al. (2019) aufbauend kann ein neuer Strang in der LL-Forschung identifiziert werden, der den gut etablierten LL-Begriff auf digitale und virtuelle Räume auszudehnen versucht, wie an der Prägung des Begriffs „virtuelle sprachliche Landschaft“ abgelesen werden kann. Parallel dazu werden soziale Netzwerke heutzutage immer mehr in touristischen Kontexten verwendet, an erster Stelle von Touristinnen, die somit – und meistens unmittelba…
Land unit definition for potential distribution of endangered species
2010
In Europe several mapping techniques exist to lay out plant distribution. Most of them, however, are focused on actual and not on potential species distribution range. Spatial predictions become more important for rare and endangered taxa because their conservation is related to existing as well as potential biotopes. The large part of detailed distribution models applies advanced statistics on a large data-set of environmental variables. Data-input availability limits the choice of the prediction model for species distribution and application of results in a detailed scale. Distribution pattern accuracy determinates its applicability in environmental management (for tracing edges, defining…
Effects of Canopy Gap Disturbance on Forest Birds in Boreal Forests
2013
We studied the effects of small-scale disturbance on breeding, forest passerine birds in an old-growth and managed boreal forests in northern Finland. Small-scale disturbance (< 2 ha) in an old-growth and managed forests originated from wind falls and small clear cuts. Continuous forest without gaps was used as a control for both management types (old-growth and managed forests). Passerines' response to disturbance was examined by estimating species richness and abundance of different ecological groups. Species richness and the total abundance of birds did not differ between gap and non-gap plots, neither did the abundance of most ecological groups. Management type or study year were the mo…
Cultural and socio-economic impacts of Mediterranean marine protected areas
2000
Marine protected areas (MPAs) may be important for protecting the marine environment, but they may also have substantial socio-cultural impacts about which very little is currently known, or acknowledged. In the Mediterranean, few data are available on the socio-economic consequences of MPAs. The present study reviews the existing data on MPAs in Spain, France, Italy and Greece. A general increase in tourist activities in Mediterranean MPAs is evident, as are increases in the abundances of larger fish species, although there are no data indicating yields for fisheries increase adjacent to MPAs. A large increase in the number of divers and vessels using MPAs has already had impacts on natura…
The red tooth hypothesis: A computational model of predator-prey relations, protean escape behavior and sexual reproduction
2009
This paper presents an extension of the Red Queen Hypothesis (hereafter, RQH) that we call the Red Tooth Hypothesis (RTH). This hypothesis suggests that predator-prey relations may play a role in the maintenance of sexual reproduction in many higher animals. RTH is based on an interaction between learning on the part of predators and evolution on the part of prey. We present a simple predator-prey computer simulation that illustrates the effects of this interaction. This simulation suggests that the optimal escape strategy from the prey's standpoint would be to have a small number of highly reflexive, largely innate (and, therefore, very fast) escape patterns, but that would also be unlearn…
Path dependence and landscape: initial conditions, contingency and sequences of events in latgale, latvia
2013
AbstractThe notion of path dependence has not yet been well explored as a tool for analysing landscape change. Within geography it is primarily economic geographers who have, up until now, shown a keen interest in this concept which stresses the role of social agency and institutions in understanding the development trajectories of regions. Further, the notion of path dependence usefully captures the idea of contingency in historical sequences. This article presents such a perspective on landscape change analysis, discussing two dominant types of sequences in path‐dependent systems. Self‐reinforcing sequences characterize the formation and long‐term reproduction of a given institutional pat…
Artificial dam lakes as suitable habitats for exotic invertebrates: Ostracoda ecology and distribution in reservoirs of the Eastern Iberian Peninsula
2014
Reservoirs are the most common deep lakes in Spain, as a consequence of water needs and dry climate. Although these aquatic systems can play an important ecological role in such an area with few large natural lakes, they can also provide new habitats for exotic species, which can colonize ecosystems that native species have not explored yet. Here we present our results for a biannual survey of the ostracod fauna from 24 reservoirs in Xuquer River basin. We check which variables affect ostracod presence, test for differences between winter and summer assemblages, and compare our data with previous available ostracod records from the same river drainage network. Our results reveal that ostrac…