Search results for "CAPE"

Pharmacogenomics in colorectal carcinomas: Future perspectives in personalized therapy

2005

The recent introduction of new drugs such as capecitabine, irinotecan, and oxaliplatinum has greatly improved the clinical outcome of patients with advanced/metastatic colorectal cancer. Nevertheless, some patients may suffer from the adverse drug reactions which will probably be the main cause of chemotherapy failure. The goal of pharmacogenomics is to find correlations between therapeutic responses to drugs and the genetic profiles of patients; the different responses to a particular drug are due, in fact, not only to the specific clinico-pathological features of the patient or to environmental factors, but also to the ethnic origins and the particular individual's genetic profile. Genes …

“L’arte dei muri a secco”, confronti tra esperienze per la conservazione del patrimonio culturale dei paesaggi rurali

2023

The European rural landscape has been designed for centuries by the art of the construction of dry stone walls and by the arrangement of terraced bands, becoming a cultural expression of identity common also to rural contexts geographically distant from each other. In 2018, eight European countries obtained the transnational recognition of the “Art of dry stone walls” in the UNESCO Intangible Cultural Heritage List. The contribution questions, on the basis of some case studies, how UNESCO recognition can concretely favor the start of that necessary support for studies and conservation of the knowledge preserved in the experience of the workers, who often lack professional recognition and re…

Die landwirthschaftlich-chemische Versuchsstation am Polytechnikum zu Riga, Lief. 2

1877

Bericht über die Thätigkeit in den Jahren 1874/75 und 1875/76.

Ausstellung des Rigaschen Gartenbauvereins

1877

The Eastern Ḫabur Archaeological Survey in Iraq Kurdistan. A preliminary report on the 2014 Season

2016

The Eastern Ḫabur Archaeological Survey in Iraq Kurdistan.

Key advantages of the leverage points perspective to shape human-nature relations

2021

This perspective paper synthesises the special issue 'Human-nature connectedness as a leverage point for sustainability transformation'. Based on the articles in this special issue, we aim to foster the operationalisation of the leverage points perspective to shape human-nature relations to enable sustainability transformations. Specifically, we draw on four key advantages of the leverage points perspective: (i) the explicit recognition of deep leverage points; (ii) the ability to examine the interactions between shallow and deep system changes; (iii) the combination of causal and teleological modes of research; and (iv) the ability to function as a methodological boundary object. The contr…

Ecological correlates of Golden Eagle Aquila chrysaetos breeding occurrence in Sardinia

2020

Capsule Golden Eagles Aquila chrysaetos in Sardinia are clustered across the main mountain ranges of the island, with a preference for undisturbed and homogeneous inland habitats. Aims To analyse habitat preferences of the Golden Eagle in Sardinia, Italy, at the landscape and home range spatial scales. Methods Landscape scale habitat preferences were analysed using the 10 × 10 km Universal Transverse Mercator grid and the home range scale was based on the spatial distribution of breeding territories. Generalized linear models were fitted with three different sets of environmental predictors (topographic, bioclimatic and land use variables) to analyse the spatial distribution of Golden Eagle…

Habitat preferences of Bonelli's Eagles Aquila fasciata in Sicily

2012

Capsule For breeding, areas dominated by extensive agricultural and rugged Mediterranean landscapes are preferred; maintenance of habitat heterogeneity and extensive agriculture are key for the conservation of this eagle. Aims To model breeding habitat preferences of Bonelli's Eagles Aquila fasciata in Sicily, where the last viable population still remains in Italy, in order to identify the most important habitats for conservation. Methods Pairs were monitored between 1990 and 2010. A case-control design through glms was used at two spatial scales: landscape and home-range. Variables included topographic, climatic, land-use, road and descriptors of habitat heterogeneity. Information-based c…

Incorporating spatial structure and stochasticity in endangered Bonelli’s eagle’s population models: implications for conservation and management

2008

Population models have played a chief role informing management decisions for the endangered Bonelli’s eagle (Aquila fasciata) in Spain. In this paper, we incorporate spatial structure and stochasticity in the construction of individual-based metapopulation models, and use these models to explore the effects of possible management actions on the persistence of the species in Spain. To build the models we used data on seven sub-populations that have experienced different trends in the last decades, and we introduced new estimates of pre-adult survival rate. The elasticity analysis of our models showed that when the interchange of individuals among sub-populations is taken into account, pre-a…

Variation in predator species abundance can cause variable selection pressure on warning signaling prey

2012

Predation pressure is expected to drive visual warning signals to evolve toward conspicuousness. However, coloration of defended species varies tremendously and can at certain instances be considered as more camouflaged rather than conspicuous. Recent theoretical studies suggest that the variation in signal conspicuousness can be caused by variation (within or between species) in predators' willingness to attack defended prey or by the broadness of the predators' signal generalization. If some of the predator species are capable of coping with the secondary defenses of their prey, selection can favor reduced prey signal conspicuousness via reduced detectability or recognition. In this study…