Search results for "CARDIOVASCOLARE"
showing 10 items of 338 documents
Antihypertensive and cardiovascular effects of combined blockade of renin-angiotensin system with ACE inhibitor and angiotensin II type 1 receptor bl…
2006
Background: In this study the effects of 24 weeks losartan and ramipril treatment, both alone and in combination, on blood pressure and left ventricular mass (LVM) and function,have been evaluated in hypertensives. Methods. 57 hypertensives with stage 1 and 2 essential hypertension were included. After 4 weeks run in, a randomized double-blind, 3 arm, double dummy, independent trial was used. All patients were randomly allocated to 3 treatment arms consisting of losartan (50 mg/daily), ramipril (5 mg/daily), and combined (losartan 50 mg/ramipril 5 mg/daily) for 24 weeks. LVM, LVM/h and other echocardiographic measurements, BUN, creatinine and clearance and potassium were determined after ru…
The Influence of Immunoglobulin Light chain Variable Gene Usage on Cardiac Function, Hematological Response, and Survival in Patients with Systemic L…
2011
FISIOPATOLOGIA E DIAGNOSTICA PER IMMAGINI IN AMBITO CARDIOVASCOLARE, RENALE E DELLO SPORT
2012
Therapeutic management of elderly hypertensives with concomitant ischaemic heart disease.
1992
CHARACTERISTICS OF ELDERLY HYPERTENSIVES: Hypertension is most prevalent in older patients and is associated with increasing morbidity and mortality with age. Elderly hypertensives often suffer from concomitant diseases, such as ischaemic heart disease, caused by age-induced modifications to the cardiovascular system, haemodynamic function and neurohormone activity. THERAPEUTIC MANAGEMENT: Therapeutic management of elderly hypertensives with concomitant ischaemic heart disease must take account of the pharmacodynamic and pharmacokinetic changes that occur in older subjects and drugs should be selected for their efficacy in both diseases. Since elderly subjects often metabolize drugs more sl…
Il paziente iperteso ad alto rischio cadiovascolare
2011
Central obesity and hypertension: the role of plasma endothelin. Am J Hypertens
1996
Hypertension and central obesity are two conditions closely linked, but the mechanisms responsible for obesity-associated hypertension are still unclear. In the last few years, several studies addressed the role of endothelin-1 (ET-1) in the development and maintenance of hypertension. This study was designed to evaluate plasma ET-1 in normotensive and hypertensive central obese subjects compared with a lean healthy group. Our final goal was to analyze the relationship between plasma ET-1, blood pressure, and left ventricular structure and function in central obese subjects (both normotensives and hypertensives). ET-levels have been assessed by the radioimmunoassay method in 20 lean normote…
Effects of a short-term hypoenergetic diet on morphofunctional left ventricular parameters in centrally obese subjects
2000
BACKGROUND: We aimed to study centrally obese subjects without other diseases, to establish whether a short-term hypoenergetic balanced regimen is able to positively modify left ventricular (LV) patterns. METHODS: We studied 32 obese subjects (out of 52 recruited for this study) with central fat distribution and without associated diseases. Each subject had undergone a moderately hypoenergetic diet for a four-month follow-up period and had a regular loss in weight. Some relevant clinical and echocardiographic parameters were evaluated. Baseline data and those evaluated at the end of the follow-up period were used for outcome analysis. RESULTS: We found a considerable reduction in LV mass an…
L’obesità fattore o co-fattore di rischio?
2005
L’obesità rappresenta odiernamente uno dei problemi più rilevanti di salute pubblica al punto che l’Organizzazione Mondiale della Sanità (WHO) sostiene che essa debba essere considerata una vera e propria “epidemia globale” . L’obesità e le malattie ad essa correlate rappresentano nei paesi occidentali una delle cause principali di mortalità precoce e di morbilità. La prevalenza dell’obesità e del sovrappeso nei paesi industrializzati ed in quelli in via di sviluppo è stimata tra il 40% ed il 60%. Negli Stati Uniti d’America, i dati più recenti del National Health and Nutrition Survey (1999-2000) sottolineano come circa il 64.5% degli adulti (67.2% uomini e 61.9% donne) sono in sovrappeso e…
Obesità, Diabete e Rischio Cardiovascolare.
2007
Il crescente interesse del mondo scientifico e delle organizzazioni sanitarie nei riguardi dell’obesità deriva dalla diffusione epidemica di questa condizione osservata negli ultimi decenni non solo nel mondo occidentale industrializzato, ma anche nei paesi in via di sviluppo (1). Nelle società più ricche, l'eccesso di peso è maggiore negli strati socio-economici più bassi e nelle fasce d'età più avanzate (2), e la percentuale di soggetti in sovrappeso (BMI>25) e con obesità franca (BMI>30) ha superato negli Stati Uniti d'America il 60% dei maschi adulti ed il 30 % delle donne tra i 50 ed i 60 anni (3). L'aspetto epidemiologico che colpisce e preoccupa di più è il trend secolare, per cui ne…