Search results for "CAS"
showing 10 items of 26112 documents
Cavernous sinus metastasis from oropharyngeal squamous cell carcinoma.
2007
Metastasis to the cavernous sinus from head and neck cancer is uncommon and has been previously reported by a few authors. It is usually a late manifestation of the primary tumor and may be the first evidence of a widespread dissemination of the disease. Main clinical findings are those related with involvement of cranial nerves III to VI as they pass through the cavernous sinus. Although diagnosis may be difficult, the appearance of clinical and radiological findings of cavernous sinus involvement in a context of head and neck cancer must alert us about an intracranial metastatic infiltration. In most cases treatment is palliative with radiotherapy and/or chemotherapy. The prognosis of thi…
Oral pigmented lesions:a retrospective analysis from Brazil
2020
Background Pigmented lesions are uncommon in the oral mucosa, and studies investigating the incidence and types of these lesions are desired to improve the diagnostic knowledge of clinicians. The aim of this study was to analyze the distribution of oral pigmented lesions in a Brazilian population. Material and Methods A retrospective descriptive cross-sectional study was performed. Oral pigmented lesions were retrieved from the files of two oral and maxillofacial pathology services from Brazil over a 45-year period (1974-2019). The clinical data and the diagnoses of each case were retrieved and included in a Microsoft Excel® database. Results From 77.074 lesions diagnosed in this period, 76…
Immunohistochemical evaluation of metallothionein in palatal mucosal cells of mice treated with 4NQO
2006
Objective: Metallothionein (MT) may play a preventive role in various carcinogenic process. 4NQO is an alkaline compound and potent mutagen that causes the formation of DNA adducts. The purpose of this study was to evaluate the immunoexpression of MT in palatal cells of mice submitted to the carcinogen 4NQO. Study design: C57BL/6 mice received applications of 4NQO to palate for periods of 8, 16, 20 and 24 weeks (experimental group). A control group received only applications of propylene glycol for the same periods. Subsequently animals of experimental and control groups were sacrificed and the palate was histologically analysed and MT immunohistochemistry performed. Results: Although morph…
A case formulation model for the assessment of psychological problems among deafblind persons
2012
In order to describe and understand possible problems associated with deafblindness we applied a functional analysis case formulation strategy and Functional Analytic Clinical Case Diagrams (FACCD). We collected clinical assessment data from deafblind persons who were experiencing multiple psychological problems as reported by their healthcare professionals. The data were collected after the healthcare professionals were trained in functional analyses and in applying FACCD. The 21 deafblind persons assessed by healthcare professionals were reported to have 3–11 psychological problems. Two case examples are given to illustrate the complexity of a deafblind person's life situation and the fun…
Histopathological parameters reported in microinvasive oral squamous cell carcinoma:a systematic review
2022
Microinvasive oral squamous cell carcinoma (OSCCmi) is an incipient stage of oral cancer. Through this systematic review, we aim to assess patterns of histopathological outcomes reported in OSCCmi cases. An online search in major databases was performed without period restriction, and 2,024 publications in English, Spanish and Portuguese were obtained. After screening and eligibility, 4 studies were selected. The risk of bias was assessed using Joanna Briggs Institute Critical Appraisal Checklist. A descriptive synthesis was conducted. All 4 publications included were retrospective, reporting a total of 116 OSCCmi patients, with a male predominance (1.6:1) and a mean age of 55.9 years. The …
Broglie and Young, visionaries who shed light in the polar topology that grounds our reality: a hypothesis
2020
Una observación matemática que relaciona los patrones fractales y la operación de convolución en el contexto del procesamiento de imágenes digitales interrumpió una investigación que nos lleva a plantear la hipótesis de que el concepto de onda de materia (o dualidad onda-partícula) se encuentra en la dicotomía entre el par débil y un topología fuerte en el ámbito del marco de atractores singulares continuos en ninguna parte diferenciables y el concepto de fotón-solitón de Vigier. Tal inferencia parece ser más evidente en la interpretación de Broglie-Bohm de la mecánica cuántica en el cruce de características locales x globales. De esto se deduce también que la relación de los fenómenos natu…
The economics of platform competition: compatibility, standardization and piracy
2013
This thesis studies the platform competition with compatibility, standardization and piracy. In the first chapter we study the role played by expectations, the strength of the network externality and product differentiation in the strategic decisions of the platforms regarding compatibility and price competition. The decision problem is modeled as a two-stage game. In the first stage platforms simultaneously and non-cooperatively choose the degree of compatibility and in the second stage platforms compete in prices. More specifically, we solve a two-stage game in which duopolists decide simultaneously and non cooperatively the degree of compatibility between their products and they compete …
Behind the scenes of artificial intelligence: a study of micro-work platforms in France
2019
Este artículo es una versión resumida del informe “Le Micro-travail en France. Derrière l’automatisation de nouvelles précarités au travail?» This article is a summarized version of the report "Le Micro-travail en France. Derrière l’automatisation de nouvelles précarités au travail?" .; International audience; Micro-work internet services allocate small, standardized tasks of data generation and annotation to crowds of providers. The outputs are mainly used to produce artificial intelligence solutions. It is an exemplary instance of the “platformization” of the economy, and of the transformations of labour that digital technologies bring about. To uncover the conditions under which micro-wo…
Concentración mínima inhibitoria (CMI) de vancomicina para Staphylococcus aureus y riesgo de bacteriemia complicada
2019
Staphylococcus aureus (S. aureus) se encuentra ampliamente distribuido por todo el mundo, comportándose tanto como patógeno como comensal. Se estima que entre un 25-50% de personas sanas puede colonizarse de manera persistente o transitoria (Longo, 2012). Este microorganismo constituye una de las principales causas de infecciones nosocomiales, siendo una de las primeras causas de bacteriemias primarias (Rigby and DeLeo, 2012) y encabezando la lista de los productores de infecciones de piel y tejidos blandos, heridas quirúrgicas, endocarditis y sepsis relacionada con catéter (Seidl et al., 2011). La bacteriemia se define como la presencia de bacterias viables en sangre; ésta puede o no estar…
Análisis de las prescripciones potencialmente inadecuadas según los criterios STOPP/START en los residentes de los centros sociosanitarios del depart…
2022
Introducción: Según la Organización mundial de la salud, el uso racional del medicamento se define como “aquel en el que el paciente recibe los fármacos apropiados para sus necesidades clínicas, en unas dosis ajustadas a su situación particular, durante un periodo adecuado y con el mínimo coste posible para él y para la comunidad”, cuando esta premisa no se cumple hablamos de prescripciones potencialmente inadecuadas. Las prescripciones inadecuadas pueden ser por indicación, cuando se prescribe un fármaco no indicado, o por omisión cuando no se prescribe a pesar de estar indicado para la prevención o tratamiento de una determinada enfermedad. Los pacientes que residen en centros sociosanita…