Search results for "CB"
showing 10 items of 647 documents
Le domande computer-based dell'indagine OCSE-Pisa e le domande INVALSI: uno studio sperimentale sul confronto tra i due strumenti di somministrazione
2016
Le valutazioni standardizzate stanno orientandosi verso la somministrazione computer-based; in quest'ottica, la ricerca si è concentrata principalmente sull'analisi della comparabilità dei risultati e sullo studio delle eventuali differenze nelle performance degli allievi dovuti al passaggio ad un nuovo ambiente di somministrazione. Tale passaggio è tutt’altro che neutro. Questo articolo presenta la prima fase di una ricerca più ampia che si propone di indagare in maniera analitica le differenze di comportamento di studenti coinvolti nella risoluzione di test somministrati in ambiente cartaceo e computerizzato. L’obiettivo è definire e validare degli strumenti di analisi che permettano di e…
Polychlorinated Biphenyls in Sediments from Sicilian Coastal Area (Scoglitti) using Automated Soxhlet, GC-MS, and Principal Component Analysis
2014
A methodology for the PAHs and PCBs congener determination in sediment samples has been revised. We determined the distributions of PAHs and PCBs in the superficial sediments of the Scoglitti (Italy) coastal area to provide data for comparison with other marine systems and to hypothesize the sources. Extraction yield, for PCB, was never less than 60% in most cases, while for PAHs, utilizing perdeuterated surrogate standard (benz[a]anthracene-d12 and anthracene-d10) was never less than 72%. The total concentration of the 16 PAHs investigated, expressed as the sum of concentrations, PAHs, varied from 1–5087 μg/kg of dry matrix, while the PCBs ranged from detection limit to 36 μg/kg of dry mat…
Removal of Chromophore-proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor
2015
Genetically encoded fluorescent markers have revolutionized cell and molecular biology due to their biological compatibility, controllable spatiotemporal expression, and photostability. To achieve in vivo imaging in whole animals, longer excitation wavelength probes are needed due to the superior ability of near infrared light to penetrate tissues unimpeded by absorbance from biomolecules or autofluorescence of water. Derived from near infrared-absorbing bacteriophytochromes, phytofluors are engineered to fluoresce in this region of the electromagnetic spectrum, although high quantum yield remains an elusive goal. An invariant aspartate residue is of utmost importance for photoconversion in…
Sporadic and Familial Variants in NF1: An Explanation of the Wide Variability in Neurocognitive Phenotype?
2020
Background: Cognitive impairment is the most common neurological manifestation in NF1 and occurs in 30-70% of NF1 cases. The onset and severity of each specific cognitive deficit varies greatly from child to child, with no apparent external causes. The wide variability of phenotype is the most complex aspect in terms of management and care. Despite multiple research, the mechanism underlying the high heterogeneity in NF1 has not yet been elucidated. While many studies have focused on the effects of specific and precise genetic mutations on the NF1 phenotype, little has been done on the impact of NF1 transmission (sporadic vs. familial cases). We used a complete neuropsychological evaluation…
Sull’attuazione degli obblighi internazionali di risposta e ripresa a fronte della pandemia di Covid-19: una prospettiva italiana
2023
This work aims at offering a critical analysis of how Italy, as one of the most early-affected countries, has responded to and is currently recovering from the Covid-19 pandemic, in the framework of international and European obligations applicable to CBRN events at large. To this end, this article will first examine the main obligations concerning «response» to and «recovery» from a pandemic event, as stemming from relevant international and European law instruments. Then, it will look at how these obligations have been implemented by Italian central and local authorities vis-à-vis the Covid-19 pandemic, while also offering some conclusive remarks on the legal meaning of the «disaster mana…
Italy
2012
Summary: 1. The constitutional protection of personal freedom. - 1.1. A little history: united Italy and the Albertine Statute. - 1.2. The current situation: the Constitution of 1948.- 1.1.1. Inviolability of personal freedom and guarantees of Habeas Corpus. - 1.1.2. Presumption of innocence and rule of treatment. - 2. Active enforcement: the system of personal precautionary measures. - 2.1. Non-custodial precautionary measures. - 2.2. Custodial precautionary measures. - 2.3. The operational core of the system. - 2.3.1. The requirement of proof: serious evidence of guilt. - 2.3.2. Precautionary needs. - 2.3.3. The selection criteria. – 3. Precautionary proceedings. - 3.1. Internal regulatio…
Discretionary Fiscal Policies over the Cycle: New Evidence Based on the ESCB Disaggregated Approach
2012
This paper explores how discretionary fiscal policies on the revenue side of the government budget have reacted to economic fluctuations in European Union countries. For this purpose, it uses data on legislated revenue changes and structural indicators provided twice per year by National Central Banks of European Union countries in the ESCB framework for analysing fiscal policy. The analysis is based on the estimation of fiscal policy rules linking these measures of legislated fiscal policy changes to the output gap and other control variables. Then, baseline results are compared with regression estimates where variations of cyclically-adjusted indicators are used as proxy for discretionary…
A Low Dose of Pure Cannabidiol Is Sufficient to Stimulate the Cytotoxic Function of CIK Cells without Exerting the Downstream Mediators in Pancreatic…
2022
Despite numerous studies conducted over the past decade, the exact role of the cannabinoid system in cancer development remains unclear. Though research has focused on two cannabinoid receptors (CB1, CB2) activated by most cannabinoids, CB2 holds greater attention due to its expression in cells of the immune system. In particular, cytokine-induced killer cells (CIKs), which are pivotal cytotoxic immunological effector cells, express a high-level of CB2 receptors. Herein, we sought to investigate whether inducing CIK cells with cannabidiol can enhance their cytotoxicity and if there are any possible counter effects in its downstream cascade of phosphorylated p38 and CREB using a pancreatic d…
Estudio comparativo de la fiabilidad y reproducibilidad en la medición de los tamaños dentarios y las medidas de la arcada dentaria entre la tomograf…
2011
La tomografía computarizada de haz cónico (CBCT) ha supuesto un gran cambio en el diagnóstico ortodóncico ya que nos proporciona información de las estructuras orofaciales en las tres direcciones del espacio, a diferencia de la radiografía convencional. A partir del CBCT podemos obtener modelos tridimensionales que reproducen tridimensionalmente la dentición del paciente, pudiendo realizar mediciones que antes realizábamos sobre los modelos de estudio. Estos nuevos modelos nos permiten realizar mediciones en dientes impactados o que no han hecho erupción, así como valorar las inclinaciones radiculares de todos los dientes. Pero para poder hacer uso de estos nuevos modelos de estudio, será n…
Dokumentārās operācijas Latvijas bankās
2021
Autore darbā analizēja Latvijas bankās pieejamos Tirdzniecības finansēšanas produktus – dokumentārās operācijas. Šo banku produktu darbība ir vērsta uz starptautisko preču tirdzniecību. Maģistra darbā autore izmantoja zinātniskās literatūras, Starptautiskās Tirdzniecības palātas publikāciju apkopojumus par šo produktu darbību. Tirdzniecības finansēšana ir tieši saistīta ar efektivitāti kā valsts ekonomikas virzītājspēks, izaugsmē un starptautiskā attīstībā – iespējams, pat stabilitātē un drošībā starptautiskajos darījumos. Pētījumā tiek analizēti šo produktu pieprasījuma dinamika Latvijas bankās, un saistītās problēmas darījumu izpildē, kuras novērtēja Latvijas uzņēmumi un šīs nozares ekspe…