Search results for "CCO"

showing 10 items of 4678 documents

Prenatal exposure to cooking gas and respiratory health in infants is modified by tobacco smoke exposure and diet in the INMA birth cohort study

2013

Background: Studies that have evaluated the association between exposure to gas appliances emissions at home with respiratory health in children obtained heterogeneous and limited results. The aim of this study is to analyze the association between the use of gas cooking at home during pregnancy and respiratory problems in children during their first year of life. Methods: In the years 2003 through 2008 pregnant women were enrolled in 4 Spanish areas and visited in different age-points following a common protocol. Outcomes studied (from a questionnaire) were any episode of lower respiratory tract infection (LRTI), wheezing, persistent cough, chestiness and otitis. The association between ex…

AdultMalemedicine.medical_specialtyPediatricsHealth Toxicology and MutagenesisRespiratory Tract DiseasesNatural GasCohort StudiesYoung AdultPregnancyLower respiratory tract infectionSurveys and QuestionnairesAparell respiratori Malalties en els infantsGas cookingTobaccomedicineHumansOtitisCookingTabac -- Efectes fisiològicsYoung adultPregnancyAir PollutantsWheezingbusiness.industryPublic healthIncidence (epidemiology)ResearchIncidenceAire -- ContaminacióPublic Health Environmental and Occupational HealthInfant NewbornInfantOdds ratiomedicine.diseaseDietOtitisFruit and vegetable consumptionSpainAir Pollution IndoorPrenatal Exposure Delayed EffectsFemaleTobacco Smoke PollutionChestinessmedicine.symptombusinessCohort study
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Physiological and cognitive responses when riding an electrically assisted bicycle versus a classical bicycle

2012

Theurel, J. | Theurel, A. | Lepers, R.; International audience; ''The present study compared the physiological responses and the subsequent cognitive performance when riding an electrically assisted (EB) versus a classical (CB) bicycle. Oxygen uptake, heart rate and leg extensor muscles electromyographic (EMG) activity were recorded in 10 subjects during a 30-min intermittent cycling exercise performed with EB versus CB. Cognitive performance was evaluated by a mail sorting test, performed at rest and after each cycling session. Averaged oxygen uptake and heat rate were significantly (P < 0.05) lower during EB cycling than during CB cycling. The EMG activities of the vastus lateralis, rectu…

AdultMalemedicine.medical_specialtyPsychometricsMuscle strainsPoison controlEXERCISEPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsFATIGUECognitionOxygen ConsumptionHeart RateMENTAL PERFORMANCEInternal medicinePERCEIVED EXERTIONHeart ratemedicineHumansMuscle SkeletalPhysiological stressWORKAnalysis of VarianceTIME''Electromyographybusiness.industryEMG ACTIVITYISOMETRIC CONTRACTIONSCognitionOxygen uptakePhysiological responsesBicyclingTIME''PHYSICAL-ACTIVITYPHYSICAL-ACTIVITY[ SCCO.NEUR ] Cognitive science/NeuroscienceExercise TestCardiologyPhysical therapyFemaleHEALTHbusinessCyclingErgonomics
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Effects of a home-based rehabilitation program in obese type 2 diabetics.

2012

International audience; OBJECTIVE: To assess, in obese type 2 diabetics (T2D), the impact of a home-based effort training program and the barriers to physical activity (PA) practice. METHOD: Twenty-three obese T2D patients (52.7 ± 8.2 years, BMI = 38.5 ± 7.6 kg/m(2)) were randomized to either a control group (CG), or an intervention group (IG) performing home-based cyclergometer training during 3 months, 30 min/day, with a monthly-supervised session. The initial and final measurements included: maximal graded effort test on cyclergometer, 6-minute walk test (6MWT) and 200-meter fast walk test (200mFWT), quadriceps maximal isometric strength, blood tests and quality of life assessment (SF- 3…

AdultMalemedicine.medical_specialtyQuadriceps strength030209 endocrinology & metabolismIsometric exerciseType 2 diabetes03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationQuality of lifeHumansMedicineOrthopedics and Sports MedicineMuscle StrengthObesityProspective Studies030212 general & internal medicineProspective cohort studyExerciseAgedbusiness.industry[SCCO.NEUR]Cognitive science/NeuroscienceRehabilitationMiddle Agedmedicine.disease3. Good healthTest (assessment)Diabetes Mellitus Type 2Home based rehabilitation[ SCCO.NEUR ] Cognitive science/NeuroscienceExercise TestPhysical therapyFemaleTraining programbusiness
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Analysis of thiamine transporter genes in sporadic beriberi

2014

Abstract Objective Thiamine or vitamin B 1 deficiency diminishes thiamine-dependent enzymatic activity, alters mitochondrial function, impairs oxidative metabolism, and causes selective neuronal death. We analyzed for the first time, the role of all known mutations within three specific thiamine carrier genes, SLC19 A2, SLC19 A3 , and SLC25 A19 , in a patient with atrophic beriberi, a multiorgan nutritional disease caused by thiamine deficiency. Methods A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence. Despite normal vitamin B 1 serum levels, his clinical picture was rapidly reverted by high-dose in…

AdultMalemedicine.medical_specialtySLC19 A- SLC25 A19SLC19 AEndocrinology Diabetes and MetabolismGene mutationBeriberimedicine.disease_causeMitochondrial Membrane Transport Proteinslaw.inventionBeriberilawInternal medicineGenotypemedicineThiamine transporterObjective: Thiamine or vitamin B1 deficiency diminishes thiamine-dependent enzymatic activity alters mitochondrial function impairs oxidative metabolism and causes selective neuronal death. We analyzed for the first time the role of all known mutations within three specific thiamine carrier genes SLC19 A2 SLC19 A3 and SLC25 A19 in a patient with atrophic beriberi a multiorgan nutritional disease caused by thiamine deficiency. Methods: A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema a subacute sensorimotor neuropathy and incontinence. Despite normal vitamin B1 serum levels his clinical picture was rapidly reverted by high-dose intramuscular thiamine treatment suggesting a possible genetic resistance. We used polymerase chain reaction followed by amplicon sequencing to study all the known thiamine-related gene mutations identified within the Human Gene Mutation Database. Results: Thirty-seven mutations were tested: 29 in SLC19 A2 6 in SLC19 A3 and 2 in SLC25 A19. Mutational analyses showed a wild-type genotype for all sequences investigated. Conclusion: This is the first genetic study in beriberi disease. We did not detect any known mutation in any of the three genes in a sporadic dry beriberi patient. We cannot exclude a role for other known or unknown mutations in the same genes or in other thiamine-associated genes in the occurrence of this nutritional neuropathy.HumansThiamineGenePolymerase chain reactionGeneticsMutationNutrition and DieteticsbiologyMembrane Transport ProteinsThiamine Deficiencymedicine.diseaseAlcoholismEndocrinologyMutationbiology.proteinThiamineMutations
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Avaliação por OCT in vivo do comprimentos axiais centrais do segmento anterior

2017

ABSTRACT Purpose: To assess changes in anatomic structures in the anterior eye segment in terms of axial lengths with accommodation via optical coherence tomography. Methods: In this observational study, 25 eyes of 25 healthy adults were examined using the Visante® omni optical coherence tomography system. Central corneal thickness, anterior chamber depth, central lens thickness, and anterior segment length were assessed. The evaluated parameters were obtained with accommodation using different stimulus vergences, namely 0.0, -1.0, -2.0, and -3.0 D. Variation of these parameters was compared among different levels of accommodation. Results: Central corneal thickness was not altered at any s…

AdultMalemedicine.medical_specialtySegmento anterior do olhoPosterior poleOcular physiologyYoung AdultOcular accommodationOptical coherence tomographyLens thicknesslcsh:OphthalmologyAnterior Eye SegmentOphthalmologymedicineHumansmedicine.diagnostic_testOptical coherence tomographybusiness.industrySegment lengthAccommodation OcularGeneral MedicineMiddle AgedAnterior eye segmentAnterior Eye SegmentOphthalmologylcsh:RE1-994Acomodação ocularTomografia de coerência ópticaFemaleTomographysense organsbusinessAccommodationTomography Optical Coherence
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Determinants of Case Fatality After Hospitalization for Stroke in France 2010 to 2015.

2019

Background and Purpose— The aims of this study were to (1) describe early and late case fatality rates after stroke in France, (2) evaluate whether their determinants differed, and (3) analyze time trends between 2010 and 2015. Methods— Data were extracted from the Système National des données de santé database. Patients hospitalized for stroke each year from 2010 to 2015, aged ≥18 years, and affiliated to the general insurance scheme were selected. Cox regressions were used to separately analyze determinants of 30-day and 31- to 365-day case fatality rates for each stroke type (ischemic, intracerebral hemorrhage, and subarachnoid hemorrhage). Results— In 2015, of the 73 124 persons hospit…

AdultMalemedicine.medical_specialtySubarachnoid hemorrhageAdolescentDatabases FactualComorbidity030204 cardiovascular system & hematologyCcomorbidityBrain Ischemia03 medical and health sciencesYoung Adult0302 clinical medicineAge DistributionCase fatality ratemedicineHumansHospital MortalityMortalitySex DistributionStrokeAntihypertensive AgentsAgedCerebral HemorrhageAdvanced and Specialized NursingAged 80 and overbusiness.industryMiddle AgedSubarachnoid Hemorrhagemedicine.diseasePrognosisComorbidity3. Good healthStrokeHospitalizationEmergency medicineHypertension[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieFemaleNeurology (clinical)FranceCardiology and Cardiovascular Medicinebusiness030217 neurology & neurosurgeryStroke
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Regular rhythmic primes boost P600 in grammatical error processing in dyslexic adults and matched controls

2020

International audience; Regular musical rhythms orient attention over time and facilitate processing. Previous research has shown that regular rhythmic stimulation benefits subsequent syntax processing in children with dyslexia and specific language impairment. The present EEG study examined the influence of a rhythmic musical prime on the P600 late evoked-potential, associated with grammatical error detection for dyslexic adults and matched controls. Participants listened to regular or irregular rhythmic prime sequences followed by grammatically correct and incorrect sentences. They were required to perform grammaticality judgments for each auditorily presented sentence while EEG was recor…

AdultMalemedicine.medical_specialtySyntax processingCognitive NeuroscienceExperimental and Cognitive PsychologySpecific language impairmentAudiology050105 experimental psychologyDyslexiaYoung Adult03 medical and health sciencesBehavioral Neuroscience[SCCO]Cognitive science0302 clinical medicineRhythmTemporal attentionmedicineHumans0501 psychology and cognitive sciencesEvoked PotentialsRhythmic primingCerebral CortexP600PsycholinguisticsP600 evoked potentialDyslexia P600 evoked potential Rhythmic priming Syntax processing Temporal attention05 social sciencesDyslexiaElectroencephalographymedicine.diseaseSyntax[SCCO.PSYC]Cognitive science/PsychologyAuditory PerceptionSpeech PerceptionFemaleGrammaticalityPsychologyPriming (psychology)Music030217 neurology & neurosurgerySentence
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Medication adherence in schizophrenia: The role of insight, therapeutic alliance and perceived trauma associated with psychiatric care

2017

Medication non adherence in schizophrenia is a major cause of relapse and hospitalization and remains for clinicians an important challenge. This study investigates the associations between insight, therapeutic alliance, perceived trauma related to psychiatric treatment and medication adherence in patients with schizophrenia. In this multicenter study, 72 patients were assessed regarding symptomatology, self-reported adherence with medication, insight, medication side-effects, therapeutic alliance and perceived trauma related to psychiatric treatment. Structural Equation Modeling (SEM) was used to test predicted paths among these variables. The data fit a model in which medication adherence…

AdultMalemedicine.medical_specialty[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologyMedication adherencePsychological TraumaStructural equation modelingMedication Adherence[ SDV.NEU.PC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior03 medical and health sciences[ SDV.NEU.SC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences0302 clinical medicineMedicineHumansIn patientPsychiatryBiological PsychiatryComputingMilieux_MISCELLANEOUS[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behaviorbusiness.industry[SCCO.NEUR]Cognitive science/Neuroscience[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesProfessional-Patient RelationsAwarenessMiddle Agedmedicine.diseaseMental healthNon adherence030227 psychiatry3. Good healthPsychiatry and Mental healthAllianceMulticenter studySchizophrenia[ SDV.NEU.NB ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology[ SCCO.NEUR ] Cognitive science/NeuroscienceSchizophreniaFemalebusiness030217 neurology & neurosurgeryClinical psychologyAntipsychotic Agents
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Inter-hemispheric remapping between arm proprioception and vision of the hand is disrupted by single pulse TMS on the left parietal cortex.

2013

International audience; Parietal cortical areas are involved in sensori-motor transformations for their respective contralateral hemifield/body. When arms of the subjects are crossed while their gaze is fixed straight ahead, vision of the hand is processed by the hemisphere ipsilateral to the arm position and proprioception of the arm by the contralateral hemisphere. It induces interhemispheric transfer and remapping. Our objective was to investigate whether a single pulse TMS applied to the left parietal cortical area would disturb interhemispheric remapping in a similar case, and would increase a simple reaction time (RT) with respect to a control single pulse TMS applied to the frontal c…

AdultMalemedicine.medical_specialtygenetic structuresCognitive NeurosciencePosterior parietal cortexExperimental and Cognitive PsychologyAudiology050105 experimental psychologyFunctional Laterality[SPI.AUTO]Engineering Sciences [physics]/Automatic03 medical and health sciencesInterhemispheric transfer0302 clinical medicineArts and Humanities (miscellaneous)Transcranial magnetic stimulation (TMS)Remapping[ SPI.AUTO ] Engineering Sciences [physics]/AutomaticParietal LobeMoro reflexDevelopmental and Educational PsychologymedicineLeft parietal areaReaction TimeVisual attentionHumans0501 psychology and cognitive sciencesAttentionSimple reaction time (RT)Brain MappingProprioception[SCCO.NEUR]Cognitive science/Neuroscience05 social sciencesContralateral hemisphereSingle pulseHandProprioceptionGazeTranscranial Magnetic StimulationNeuropsychology and Physiological PsychologyStartle reflex[ SCCO.NEUR ] Cognitive science/NeuroscienceArmVisual PerceptionPsychologyNeuroscience030217 neurology & neurosurgeryArm positionPsychomotor PerformanceBrain and cognition
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Sex differences in interhemispheric communication during face identity encoding: Evidence from ERPs

2013

Sex-related hemispheric lateralization and interhemispheric transmission times (IHTTs) were examined in twenty-four participants at the level of the first visual ERP components (P1 and N170) during face identity encoding in a divided visual-field paradigm. While no lateralization-related and sex-related differences were reflected in the P1 characteristics, these two factors modulated the N170. Indeed, N170 amplitudes indicated a right hemisphere (RH) dominance in men (and a more bilateral functioning in women). N170 latencies and the derived IHTTs confirmed the RH advantage in men but showed the reverse asymmetry in women. Altogether, the results of this study suggest a clear asymmetry in m…

AdultMalemedicine.medical_specialtysex-related differencesmedia_common.quotation_subject[ SCCO.PSYC ] Cognitive science/PsychologyAudiologybehavioral disciplines and activitiesFunctional Laterality050105 experimental psychologyLateralization of brain functionDevelopmental psychology03 medical and health scienceshemispheric communication0302 clinical medicinePerceptionNeural PathwaysmedicineHumansEncoding (semiotics)0501 psychology and cognitive sciencesRight hemisphereEvoked Potentialsmedia_commonSex CharacteristicsGeneral Neurosciencehemispheric specialization05 social sciencesBrainElectroencephalographyGeneral MedicineDominance (ethology)Face identityFace[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC][SCCO.PSYC]Cognitive science/PsychologyVisual PerceptionFemaleDivided visual field paradigmface identity encoding[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Psychologyn170-ihttsPhotic Stimulation030217 neurology & neurosurgerydivided-visual field paradigm
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