Search results for "CD"
showing 10 items of 4072 documents
Veiksmīgas ārzemju un Latvijas franšīzes piemērs un analīze
2015
Šī diplomdarba tēmas aktualitātes pamatojums ir tāds, ka pastāv vairāki faktori, kas kavē starptautiskā biznesa attīstību. Lai atrisinātu šo problēmu, ir vajadzīgi jauni ekonomiskie mehānismi, viens no kuriem ir franšīze, kas ļauj palielināt rentabilitāti. Diplomdarba mērķis ir noskaidrot franšīzes attīstības iespējas, apskatīt franšīzes ietekmējošus faktorus, kā arī analizēt franšīzes izdevigumu Latvijā uz veiksmīgas ārzemju un Latvijas franšīzes piemēra. Diplomdarbs sastāv no 3 daļām. Pirmajā ir izpētīti franšīzes teorētiskie aspekti un franšīzes kā starptautiskā biznesa iespējas, otrajā ir apskatīti franšīzes ietekmējošie faktori un trešajā tiek izanalizēti veiksmīgas ārzemju un Latvijas…
Localization of Viral Epitope-Specific CD8 T Cells during Cytomegalovirus Latency in the Lungs and Recruitment to Lung Parenchyma by Airway Challenge…
2021
Interstitial pneumonia is a life-threatening clinical manifestation of cytomegalovirus infection in recipients of hematopoietic cell transplantation (HCT). The mouse model of experimental HCT and infection with murine cytomegalovirus revealed that reconstitution of virus-specific CD8+ T cells is critical for resolving productive lung infection. CD8+ T-cell infiltrates persisted in the lungs after the establishment of latent infection. A subset defined by the phenotype KLRG1+CD62L− expanded over time, a phenomenon known as memory inflation (MI). Here we studied the localization of these inflationary T effector-memory cells (iTEM) by comparing their frequencies in the intravascular and transm…
Erratum to «Institutions and conflicts of interests in the international accounting regulation: The Spanish financial industry case»
2015
Instituciones e intereses en conflicto ante la regulación contable internacional: el caso del sector financiero españo Begoña Giner
From accrued to paid income tax: A review of effective tax rate calculation
2019
Los estudios que han tratado de valorar la presión fiscal de una sociedad como consecuencia del impuesto sobre sociedades recurren generalmente al impuesto devengado como aproximación, aun sabiendo que difícilmente coincidirá con la cantidad verdaderamente pagada. Sin embargo, como consecuencia de los cambios producidos en las cuentas anuales para su adaptación a la normativa internacional, contamos con una información adicional en el balance (activos y pasivos fiscales) que hace posible obtener el importe del impuesto sobre beneficios pagado por las empresas, pudiendo medir de forma más precisa su verdadera presión fiscal. Teniendo en cuenta esta circunstancia y que ya disponemos de inform…
TOWARDS AN ADVANCED CONSERVATION STRATEGY: A STRUCTURED DATABASE for SHARING 3D DOCUMENTATION between EXPERT USERS
2019
Abstract. Nowadays, the researchers in Cultural Heritage fields investigate more and more about advanced conservation strategies that comprehend the possibility to share and use 3D models and structured information related to them. One of the modern method adopted to achieve this goal is to use structured web-platform. These are online systems that can handle data, created to contain and support precise information. They simultaneously respond to the need for a common ground for different expert users and of a unique tool where to store several kinds of data, coming from heterogeneous sources. The article aims to show how it is possible to build a valid tool for the conservation and monitor…
An updated insight into the Sialotranscriptome of Triatoma infestans: developmental stage and geographic variations
2014
Background Triatoma infestans is the main vector of Chagas disease in South America. As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting and promoting vasodilation. These salivary components can be immunologically recognized by their vector's hosts and targeted with antibodies that might disrupt blood feeding. These antibodies can be used to detect vector exposure using immunoassays. Antibodies may also contribute to the fast evolution of the salivary cocktail. Methodology Salivary gland cDNA libraries from nymphal and adult T. infestans of breeding colonies originating from different loc…
Qualitative and Quantitative Analysis of Cardiac Progenitor Cells in Cases of Myocarditis and Cardiomyopathy
2018
We aimed to identify and quantify CD117+ and CD90+ endogenous cardiac progenitor cells (CPC) in human healthy and diseased hearts. We hypothesize that these cells perform a locally acting, contributing function in overcoming medical conditions of the heart by endogenous means. Human myocardium biopsies were obtained from 23 patients with the following diagnoses: Dilatative cardiomyopathy (DCM), ischemic cardiomyopathy (ICM), myocarditis, and controls from healthy cardiac patients. High-resolution scanning microscopy of the whole slide enabled a computer-based immunohistochemical quantification of CD117 and CD90. Those signals were evaluated by Definiens Tissue Phenomics® Technology. Co-loca…
Calcareous nannofossil events in the Lower-Mildle Pleistocene transition at the Montalbano Jonico section and ODP site 964: Calibration with isotope …
2004
We present quantitative data on calcareous nannofossil biostratigraphy in the section of Montalbano Jonico (Southern Italy). This is one of the candidate Global Statotype Section and Point (GSSP) of the Middle Pleistocene. The first common occurrence (FCO) and last common occurrence (LCO) of Reticulofenestra asanoi are well detectable in the section and are here proposed as additional events for improving biostratigraphic resolution in the interval corresponding to the transition between the small Gephyrocapsa Zone and Pseudoemiliania lacunosa Zone. The potential value of the bioevents is tested in a Mediterranean deep-sea core of ODP Site 964, located in the Ionian Sea. At Site 964 the FCO…
Human Memory Th17 Cell Populations Change Into Anti-inflammatory Cells With Regulatory Capacity Upon Exposure to Active Vitamin D
2019
Autoimmune diseases are characterized by an aberrantly activated immune system, resulting in tissue damage and functional disability in patients. An important therapeutic goal is to restore the deregulated immunological balance between pro- A nd anti-inflammatory T cells. This imbalance is illustrated by elevated levels and activity of memory Th17 cell populations, such as Th17, Th1/Th17, and Th17.1 cells, in various autoimmune diseases. These cells are characterized by the chemokine receptor CCR6, RORC expression and production of IL-17A, IFNγ, and TNFα. Using rheumatoid arthritis (RA) as a model of autoimmune disease, we here demonstrate that pro-inflammatory memory CCR6+ Th cells can swi…
2018
Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma membrane “master organizers.” They form Tspan-enriched microdomains (TEMs or TERMs) through lateral association with one another and other membrane proteins. If multiple microdomains associate with each other, larger platforms can form. For infection, viruses interact with multiple cell surface components, including receptors, activating proteases, and signaling molecules. It appears that Tspans, such as CD151, CD82, CD81, CD63, CD9, Tspan9, and Tspan7, coordinate these associations by concentrating the interacting partners into Tspan platforms. In addition to mediating viral attachment and entry, these …