Search results for "CEI"
showing 10 items of 1294 documents
Chromoscopy-Guided Endomicroscopy Increases the Diagnostic Yield of Intraepithelial Neoplasia in Ulcerative Colitis
2007
Background & Aims: Because of the large number of biopsy specimens, surveillance colonoscopy in ulcerative colitis (UC) is currently time consuming and significant flat lesions still may be missed. In this study we assessed the value of combined chromoscopy and endomicroscopy for the diagnosis of intraepithelial neoplasias in a randomized controlled trial. Methods: A total of 161 patients with long-term UC in clinical remission were randomized at a 1:1 ratio to undergo conventional colonoscopy or chromoscopy with endomicroscopy. Eight patients were excluded because of insufficient bowel preparation. In the conventional colonoscopic group (n = 73), random biopsy examinations and targeted bio…
Novel preoperative predictive score to evaluate lymphovascular space involvement in endometrial cancer: an aid to the sentinel lymph node algorithm.
2020
IntroductionSentinel lymph node (SLN) dissection has been recognized as a valid tool for staging in patients with endometrial cancer. Several factors are predictors of recurrence and survival in endometrial cancer, including positive lymphovascular space invasion. The aim of this study is to formulate a pre-operative score that, in the event of no-SLN identification, may give an estimate of the true probability of lymphovascular space invasion and guide management.MethodologyThis was a multi-institutional retrospective study conducted from January 2007 to December 2017. We included all patients with any grade endometrial tumor with a complete pathological description of the surgical specime…
Psychometric properties of 12-item self-administered World Health Organization disability assessment schedule 2.0 (WHODAS 2.0) among general populati…
2019
WHODAS 2.0 is a unified scale to measuring disability across diseases, countries, and cultures. The objective was to explore the available evidence on the psychometric properties of 12-item self-administered WHODAS 2.0 among a general population and people with non-acute physical causes of disability.Five databases Medline, Embase, Web of Science, Scopus, and PsycINFO were searched for papers related to the validity, reliability, responsiveness, minimal clinically important difference or minimal detectable change of 12-item self-administered WHODAS 2.0. In order to avoid missing any potentially relevant studies, the search clauses were left as generic as possible and the refining search was…
Prevalence and Sociodemographic Predictors of Mental Health in a Representative Sample of Young Adults from Germany, Israel, Poland, and Slovenia: A …
2022
The aim of this cross-national longitudinal study was to evaluate the prevalence and sociodemographic predictors of mental health indicators (coronavirus-related post-traumatic stress disorder (PTSD), perceived stress, anxiety, depression, and suicidal/self-harm ideation) during the coronavirus disease-2019 (COVID-19) pandemic in a three-month period among representative samples of young adults from Germany, Israel, Poland, and Slovenia. The participants were 1724 young adults between 20 and 40 years of age (M = 30.74, SD = 5.74). The first measurement (T1) was in February 2021 and the second (T2) was in May–June 2021. The samples were representative of young adults in each country: Germany…
Does optimism mediate the relationship between Big Five and perceived stress? A study with Spanish adolescents
2021
Los resultados de investigación han mostrado la existencia de relaciones entre los Cinco Grandes factores de personalidad, Optimismo y Estrés Percibido. El objetivo del estudio es explorar, mediante modelos de ecuaciones estructurales, el posible papel mediador que se ha sugerido podría desempeñar Optimismo en esta relación. También, se explora a través de un análisis multi-grupo la invarianza por sexo de los resultados. Un total de 611 adolescentes españoles completaron de forma anónima los cuestionarios BFQ, LOT-R y PSS. Optimismo se asoció positivamente asociado con los rasgos de personalidad y negativamente con Estrés Percibido. El Estrés se relacionó negativamente con Estabilidad Emoc…
Flow cytometric analysis of concanavalin A binding to isolated Golgi fractions from rat liver.
1993
Flow cytometry (FCM) has been used repeatedly to study lectin binding to whole cells. However, there are very few attempts to analyze glycoconjugates in isolated subcellular organelles. We have applied FCM to quantitate the specific binding of fluorescein-conjugated concanavalin A (FITC-Con A) to isolated cis and trans fractions of rat liver Golgi complex, the cell compartment involved in glycoprotein maturation and sorting. Our results show similar intensities of Con A-specific binding in the two fractions. Using this method we show a decreased FITC-Con A binding to both Golgi fractions in ethanol-treated rats, which is consistent to previous work on alcoholic effects on galactosyltransfer…
Analysis of a database to predict the result of allergy testing in vivo in patients with chronic nasal symptoms and the development of the software A…
2014
Background. This thesis consist of parts(i)Introduction in wich we present the clinical problem of rhinitis;(ii)the methods to evaluate the diagnostic choises;(iii)the rational errors in Allergy,(iv)the experimental part of thesis with wich we developed the software ARTSTAT,wich is the application of the analysis reported.Objective: We studied the ability of the logistic regression model obtained by the evaluaqtion of a database, to detect patients with positive allergy skin prick test(SPT)and patients with negative SPT. The model developed was valitated using the data set obtained from another medical institution. Methods: The analysis was carried out using a database obtained from a quest…
Projekts: Uzņēmuma "Homeopathy" dibināšana
2016
Maģistra darba izstrades tēma ir uzņēmuma biznesa plāna sastadīšana ar mērķi atvērt jaunu uzņēmumu. Biznesa plāna mērķis ir panākt visizdevigāko variantu starp to, ko jūs gribat darīt, un to, ko varat izdarīt. Plāns apraksta nepieciešamos pasākumus, kas veicami tūlīt, un tos, kas plānojami turpmākajā laika posmā. Uzņēmējdarbības vide strauji mainās, tāpēc arī biznesa plāns nevar būt nemainīgs, kā akmenī iekalts. Plānam jābūt elastīgam, tas jāmaina un jāpielago situācijas izmaiņām1 Darba autore aizdomājās par dažādām ārstēšanas metodēm un to ietekmi uz cilvēka tālāko veselību un pašsajūtu. Apskatoties uz zālēm, kas ir pieejamas aplopatiskajas aptiekās, un īpaši pievēršot uzmanību to instrukc…
Coconut oil: non-alternative drug treatment against alzheimer's disease
2015
Introducción: la enfermedad de Alzheimer es la demencia más prevalente en la actualidad. En cuanto al tratamiento, no existe cura farmacológica definitiva, con lo cual son necesarias nuevas alternativas terapéuticas. En este sentido, los triglicéridos de cadena media suponen una fuente directa de energía celular y pueden ser una alternativa no farmacológica a la muerte neuronal por falta de la misma, que se produce en los enfermos de Alzheimer. Objetivo: evaluar el impacto que tiene el aceite de coco en la evolución de la demencia tipo Alzheimer, en cualquier grado de demencia. Asimismo, determinar si existe influencia en dicha mejora, de variables como el sexo y padecer o no diabetes melli…
Immuno-SLM—a combined sample handling and analytical technique
2004
Immuno-supported liquid membrane (immuno-SLM) extraction is a new technique that makes use of antibody (Ab)-antigen interactions as the "extraction force" to drive the mass transfer in a selective way. In immuno-SLM, anti-analyte (Ag) Abs are introduced into the acceptor phase of the SLM unit to trap the Ag that passes from the flowing donor through the SLM into the stagnant acceptor. The amount of immuno-extracted analyte (AbAg) is quantified by connecting the immuno-SLM unit on-line with a non-competitive heterogeneous fluorescence flow immunoassay (FFIA) that makes use of a fluorescein-labeled analyte tracer that titrates the residual excess of Ab present in the acceptor. A restricted ac…