Search results for "CEI"
showing 10 items of 1294 documents
Software-supported image quantification of angiogenesis in an in vitro culture system: application to studies of biocompatibility
2002
Healing of soft tissue trauma and bone discontinuities following implantation involves acute inflammatory reactions and the formation of blood vessels (angiogenesis). During angiogenesis new capillary vessels arise from the existing vasculature. Endothelial cells (EC) are the major cell type involved in angiogenesis. Corrosion of orthopaedic metallic implant materials (e.g. CoCr alloys) can cause locally high concentrations of heavy metal ions in the peri-implant tissues. Some divalent metal ions (Co2+, Ni2+, Zn2+) lead to the activation of EC in vitro. Upon exposure to these ions. EC release cytokines and chemokines and increase the expression of cell surface adhesion molecules, which repr…
Jet-vortex spray freeze drying for the production of inhalable lyophilisate powders
2016
Abstract Spray-freeze-dried powders were suggested for nasal, epidermal (needle-free injection) or pulmonary application of proteins, peptides or nucleic acids. In spray-freeze-drying processes an aqueous solution is atomized into a refrigerant medium and subsequently dried by sublimation. Droplet-stream generators produce a fast stream of monodisperse droplets, where droplets are subject to collisions and therefore the initial monodispersity is lost and droplets increase in diameter, which reduces their suitability for pulmonary application. In jet-vortex-freezing, a droplet-stream is injected into a vortex of cold process gas to prevent droplet collisions. Both the injection position of t…
A methodology to assess the effect of sweat on infrared thermography data after running: Preliminary study
2020
Abstract The aim of this technical report is to present a preliminary study carried out to define the methodology to be employed for further research on assessing the effect of sweating on infrared thermography and thermal contact sensors after moderate intensity running. Nine recreational runners participated in this preliminary study. Participants ran for 35 min (5 min warm-up and 30 min at a rate of perceived exertion rate of 12 points on the 6–20 points Borg scale). Skin temperature (infrared thermography, Flir E60bx; four thermal contact sensors, IButton DS1923 Hygrochron) and relative humidity (thermal contact sensors) were measured on the anterior thigh on both lower limbs before and…
The effect of extracellular matrix proteins on the cellular response of HUVECS and HOBS after covalent immobilization onto titanium
2014
Biomimetic surface modifications are regarded as promising approach to stimulate cellular behavior at the interface of implant materials. Aim of the study was an evaluation of the cellular response of human umbilical cord cells (HUVECS) and human osteoblasts (HOBS) on titanium covalently coated with the extracellular matrix (ECM) proteins fibrinogen, collagen, laminin, and osteopontin. For the surface modification, titanium discs were first amino-functionalized by plasma polymerization of allylamine. The ECM protein conjugation was performed using the linker molecule α, ω-bis-N-hydroxysuccinimide polyethylene glycol (Di-NHS linker). For surface characterization, infrared spectroscopy and fl…
Evaluation of polyalkylcyanoacrylate nanoparticles as a potential drug carrier: preparation, morphological characterization and loading capacity.
1993
Some physicochemical behaviours were investigated of polyethyl- (PECA) and polyisobutylcyanoacrylate (PICA), which, in recent years, have been proposed as nanoparticle colloidal systems for drug carrying. We observed the influence of preparation conditions, such as pH value and surfactant concentration, on parameters such as particle size and polymer molecular weight. Lower operating pH values (0-2) resulted in smaller nanoparticles than those prepared at pH 5.5. The polymer molecular weight was also a function of pH: low molecular weight at low pH and vice-versa. The surfactant concentration positively influenced main particle size and polymer molecular weight. These trends were independen…
Chip-to-chip plasmonic interconnects and the activities of EU project NAVOLCHI
2012
In this paper, the chip-to-chip interconnection architecture adopted by the EU-project NAVOLCHI are discussed. The plasmonic physical layer consisting of a plasmonic nanoscale laser, a modulator, an amplifier and a detector is introduced. Current statuses of the plasmonic devices are reviewed.
Wall assemblies U-value calculation in test buildings using constant power heating
2018
Abstract Building envelopes under various climates behave differently, in this paper the actual thermal transmittance or U-value of five different wall assemblies are evaluated and compared with values, calculated using standard EN ISO 6946. The experiment is carried out in five test buildings with equal spatial orientation, the same ceiling and floor assemblies as well as the same windows and doors mounted in each building. The thermal transmittances for these partitions are assumed to be well known and therefore, by knowing temperature difference and heat sources inside the building, the thermal transmittance of wall assembly can be calculated. It is shown that for small buildings the cor…
Energy-Efficient Resource Optimization with Wireless Power Transfer for Secure NOMA Systems
2018
In this paper, we investigate resource allocation algorithm design for secure non-orthogonal multiple access (NOMA) systems empowered by wireless power transfer. With the consideration of an existing eavesdropper, the objective is to obtain secure and energy efficient transmission among multiple users by optimizing time, power and subchannel allocation. Moreover, we also take into consideration for the practical case that the statistics of the channel state information of the eavesdropper is not available. In order to address the optimization problem and its high computational complexity, we propose an iterative algorithm with guaranteed convergence to deliver a suboptimal solution for gene…
The Transition from Middle School to High School: The Mediating Role of Perceived Peer Support in the Relationship between Family Functioning and Sch…
2018
The study focused on the transition from middle school to high school and aimed to verify the mediating role that perceived peer support may play in the relationship between family functioning in middle school and school satisfaction in high school. In middle school (Wave 1), participants were 208 adolescents (106 boys and 102 girls) aged 12–13 years (M = 12.56; SD = .61), attending the last classes of two middle public schools located in Italy. One year later (Wave 2), 155 adolescents (76 boys and 79 girls) participated again in the study when they attended the first classes of high school (M = 13.91; SD = .75). Participants completed the Italian Version of Family Assessment Device and the…
Changes in Stress, Coping Styles, and Life Satisfaction between the First and Second Waves of the COVID-19 Pandemic: A Longitudinal Cross-Lagged Stud…
2021
In this study, we aimed to explain the interplay mechanism between stress, life satisfaction, and coping styles among university students. A cohort study was performed during the first (wave 1; W1) and second (wave 2; W2) waves of the Coronavirus disease 2019 (COVID-19) pandemic. The total sample included 231 university students, of which 59.31% were women. The Satisfaction with Life Scale (SWLS), Perceived Stress Scale (PSS), and Coping Inventory for Stressful Situations (CISS) were included in one online survey. Stress, emotion-oriented, and avoidance-oriented coping styles increased from W1 to W2 of the COVID-19 pandemic, while life satisfaction and task-oriented coping decreased. The pa…