Search results for "CELL"

Domesticating the future?: Citizen’s income discussion in Estonia

2018

ABSTRACTCitizen’s income is an idea that is currently gaining ground in many parts of the world. The prospect of disappearing jobs and social exclusion that the globalized world faces has given the...

The evaluation of tumor budding in oral tongue squamous cell carcinoma patients: a novel prognostic histopathological grading system

2020

Mast cells as protectors of health.

2019

Mast cells (MCs), which are well known for their effector functions in T(H)2-skewed allergic and also autoimmune inflammation, have become increasingly acknowledged for their role in protection of health. It is now clear that they are also key modulators of immune responses at interface organs, such as the skin or gut. MCs can prime tissues for adequate inflammatory responses and cooperate with dendritic cells in T-cell activation. They also regulate harmful immune responses in trauma and help to successfully orchestrate pregnancy. This review focuses on the beneficial effects of MCs on tissue homeostasis and elimination of toxins or venoms. MCs can enhance pathogen clearance in many bacter…

Metabolic Changes in Tumor Microenvironment: How Could They Affect γδ T Cells Functions?

2021

The metabolic changes that occur in tumor microenvironment (TME) can influence not only the biological activity of tumor cells, which become more aggressive and auto sustained, but also the immune response against tumor cells, either producing ineffective responses or polarizing the response toward protumor activity. γδ T cells are a subset of T cells characterized by a plasticity that confers them the ability to differentiate towards different cell subsets according to the microenvironment conditions. On this basis, we here review the more recent studies focused on altered tumor metabolism and γδ T cells, considering their already known antitumor role and the possibility of manipulating th…

Extracellular Vesicles as Shuttles of Tumor Biomarkers and Anti-Tumor Drugs

2014

Extracellular vesicles (EV) include vesicles released by either normal or tumor cells. EV may exceed the nanometric scale (microvesicles), or to be within the nanoscale, also called exosomes. Thus, it appears that only exosomes and larger vesicles may have the size for potential applications in nanomedicine, in either disease diagnosis or therapy. This is of particular interest for research in cancer, also because the vast majority of existing data on EV are coming from pre-clinical and clinical oncology. We know that the microenvironmental features of cancer may favor cell-to-cell paracrine communication through EV, but EV have been purified, characterized, and quantified from plasma of tu…

HPLC/HRMS and GC/MS for Triacylglycerols Characterization of Tuna Fish Oils Obtained from Green Extraction

2023

Background: Fish oil is one of the most common lipidic substances that is consumed as a dietary supplement. The high omega-3 fatty acid content in fish oil is responsible for its numerous health benefits. Fish species such as mackerel, herring, tuna, and salmon are particularly rich in these lipids, which contain two essential omega-3 fatty acids, known as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Objectives: Due to the scarcity of information in the literature, this study aimed to conduct a qualitative and quantitative characterization of triglycerides (TAGs) in crude tuna fish oil using HPLC/HRMS. Fatty acid (FA) determination was also performed using GC/MS. The tuna fis…

Planning, implementing and evaluating social and emotional skills course for coaches

2015

ABSTRACT Antell, Sanna. 2015. Planning, implementing and evaluating social and emotional skills course for coaches. Master’s Thesis in Sport and Exercise Psychology. Department of Sport Sciences. University of Jyväskylä. 79 pages. Research on Social and Emotional Skills among sport coaches is limited. Therefore, the purpose of this study was to plan, implement and evaluate a course in Social and Emotional Skills for sport coaches and instructors. The aim was to study the learning processes and the experiences of the participants. Traditionally coaches in martial arts lead with an authoritarian style; consequently the aim of this course was to show a different way of interacting with trainee…

Associations Between Adolescents' Subjectively Experienced Emotions and Psychophysiological Reactions in Achievement Situations

2022

This study investigated associations of early adolescents' (N=190, median age = 12) subjectively experienced emotions and psychophysiological reactions in achievement situations. Self-reported questions assessed adolescents' experienced emotions. Additionally, adolescents' autonomic nervous system (ANS) reactions were recorded; skin-conductance response (SCR) and heart rate (HR) were used to measure sympathetic nervous system activity, and heart rate variability (HRV) was used to measure parasympathetic nervous system activity. The between-person-level results of multilevel modeling showed that increased HR was associated with higher levels of hope and fear and that decreased SCR was associ…

Emergency Response Model as a part of the Smart Society

2021

Centralized hybrid emergency model with predictive emergency response functions is necessary when the purpose is to protect the critical infrastructure (CI). A shared common operational picture among Public Protection and Disaster Relief (PPDR) authorities means that a real-time communication link from the local level to the state-level exists. If a cyberattack would interrupt electricity transmission, telecommunication networks will discontinue operating. Cyberattack becomes physical in the urban and maritime area if an intrusion has not been detected. Hybrid threats require hybrid responses. The purpose of this qualitative research was to find out technological-related fundamental risks …

Les appellations d'origine et le débat sur la typicité dans la première moitié du XXe siècle : le rôle du syndicalisme vitivinicole bourguignon et la…

2010

International audience