Search results for "CELLULE"

Bleomycin induced pulmonary toxicity and its subpleural onset

2016

Idiopathic Pulmonary Fibrosis (PF) is a rare and devastating disease without efficient treatment at this time. Idiopathic FP is characterized by accumulation of myofibroblasts and has a typical sub-pleural onset suggesting a role of the pleura in the disease. Transforming Growth Factor (TGF)-ß1 induces transformation of pleural mesothelial cells (PMC) into active cells exhibiting myofibroblast phenotype. Heat shock proteins can act as regulator of the TGF-ß1 signaling. A role for caspase-1/IL-1ß axis has already been described in animal models of PF.The heat shock protein AlphaB-crystallin has been studied in PF at the PMC level and the importance of caspase-1/IL-1ß axis has been investigat…

Decremento delle cellule T regolatorie (Treg) CD4+CD25+FOXP3+ nei linfociti periferici dei pazienti affetti da diabete di tipo 1.

2006

Contribution and limitation of infrared spectroscopy technique to understand physisorption processes on MFI zeolites

2011

This manuscript is devoted to the study of adsorption processes by FTIR spectroscopy. The experimental results concern the adsorption of ethylene, trichloroethylene, tetrachloroethylene, sulfur hexafluoride or p-xylene on MFI zeolites, more especially on silicalite-1. The first step of the work was to develop a new experimental device and procedure in order to obtain reliable absorption infrared data and to improve results previously obtained by a prototype. The first main result is to characterize, maybe for the first time, the evolution of the spectrum of the adsorbent all during the adsorption process. Experiments reveal that the zeolite infrared spectrum undergoes strong modifications w…

Circulating markers of retinal and optic nerve lipids

2013

Purpose Blood lipids are frequently used as a surrogate of lipid composition of peripheral tissues. Even if it is well accepted, such a relationship has never been clearly demonstrated for the eye. The aim of this study was to determine in human samples whether a lipidomic approach based on red blood cells could reveal associations between circulating and ocular lipid profiles. Methods Red blood cells, retinas and optic nerves were collected from 9 human donors. The lipidomic analyses on these tissues were done by both, gas chromatography and liquid chromatography coupled to an electrospray ionization source-mass spectrometer (LC-ESI-MS/MS). Results Gas chromatographic approach did not show…

Synthesis of oligomers and polymers doped with porphyrins for solar energy conversion

2017

The aim of this thesis was to elaborate new electron donor materials for organic solarcells. This emerging photovoltaic technology is rapidly expanding, and has yet already reached the limit for its large-scale commercialization. The low manufacturing cost of organic photovoltaic devices make then competitive face to well-established inorganic technologies. Their biggest advantage is their weight and their mechanical properties which make them flexible. They should play a key role in future as a complement to classic solar cells, with their use in specific applications. We developed polymers by using different chomophores, well-known for their interesting photophysical properties: the porph…

Study of optical and magneto-optical processes in cesium, rubidium and potassium micro- and nano-metric thin atomic layers

2016

It has been investigated the D1 line transitions of 39K atoms in external magnetic fields using nanocells for the cases of sigma+ and pi polarizations of laser radiation. For the first time it is demonstrated the decoupling of electronic total angular momentum J and nuclear momentum I (complete hyperfine Paschen-Back regime) in external magnetic field. For 39K the decoupling takes place at B >> 165 G. In the case of linear polarization it is shown that for B > 400 G the transmission spectrum consists of 2 groups of transitions and each group contains of one so-called "Guiding transition" (GT). The GT indicates the asymptotic value of all transitions probabilities in the group and the freque…

Formation of narrow optical resonances in thin atomic vapor layers of Cs, Rb, K and applications.

2019

This thesis presents the study of coherent light interaction with a sub-wavelength atomic alkali vapor layer confined in a nano-cell and applications for the formation of narrow optical resonances.We develop a theoretical model describing the resonant interaction of the laser light with the thin alkali vapor layer in the presence of an external static magnetic field. We show that due to a transient regime of interaction, only slow atoms contribute to the signal and their transmission spectrum is essentially Doppler-free. The nature of the obtained spectra makes the transmission spectroscopy from a nano-cell a convenient technique to perform studies of closely-spaced atomic transitions and i…

Selective reflection spectroscopy of alkali vapors confined in nanocells and emerging sensing applications

2019

This thesis is aimed at studying the resonant interaction of a laser radiation with an atomic alkali vapor layer of wavelength-scale thickness confined in an optical nanocell; and emerging sensing applications.We focus our attention on the selective reflection arising at the interface between a dielectric window and a resonant alkali vapor, and show that the derivative of selective reflection spectra exhibit narrow resonances whose maxima are located exactly at atomic resonance frequencies. These resonances are observed with a spectral linewidth up to fifteen times smaller than the Doppler linewidth of the medium and their amplitudes scale linearly with respect to the transitions ones. Owin…

Hautes Pressions : les Nouveaux Enjeux

2012

pour le champs 'auteurs', les Directeurs de publications apparaissent en premier puis le Directeur de collection.; International audience; P. 11|Introduction / Camille Loupiac, Alain Prat, Yann Le Godec|P. 15|Dernier inventaire avant cessation d’activité / H. Cardon|P. 31|La biologie sous pression : de la molécule au procédé / Roger Fourme, Gérard Hamel, Camille Loupiac, Jean-Marie Perrier-Cornet, Serge Pin, Julien Roche|P. 57|Synthèse de nouveaux matériaux à propriétés remarquables sous conditions extrêmes / Yann Le Godec et Pierre Toulemonde|P. 87|Physique sous haute pression: résultats récents et perspectives / Alain Polian|P. 107|Les déchets sous pression: un traitement ou une valorisat…

Active oxygen species production in tobacco cells elicited by cryptogein

1997

International audience