Search results for "CERAMICS"
showing 10 items of 1599 documents
New hydrogel matrices containing an anti-inflammatory agent. Evaluation of in vitro release and photoprotective activity.
2002
In the present work. the preparation and characterization of hydrogels based on alpha,beta-polyaspartylhydrazide (PAHy) chemically crosslinked with ethyleneglycol diglycidylether (EGDGE) containing Tolmetin sodium salt, are reported. In particular, these samples have been prepared both as water swellable microparticles and as gels at two different crosslinking degrees. The incorporation of Tolmetin sodium salt in PAHy-EGDGE microparticles has been performed after the crosslinking reaction by a soaking procedure or during the formation of the network. The influence of drug loading procedure on Tolmetin release has been evaluated by performing in vitro release study in simulated gastrointesti…
BMP-2 and bFGF release and in vitro effect on human osteoblasts after adsorption to bone grafts and biomaterials.
2012
Objectives Combination of scaffolds and growth factors is a promising option for several clinical problems in bone biomaterials. Simplified growth factor loading by adsorption from aqueous solution is one important option for this technology. We evaluated the adsorption followed by PBS rinsing, release and biological effect of transient loading with basic fibroblast growth factor (bFGF) and bone morphogenic protein 2 (BMP-2) on fresh frozen bone, processed bone matrix, collagen, and a ceramic material with immunofluorescence, enzyme-linked immunosorbent assay (ELISA), and qRT-PCR. Materials and methods The study consisted of three in vitro experiments (immunofluorescence, ELISA, and qRT-PCR…
Perfluoroalkylated amphiphilic MUC1 glycopeptide antigens as tools for cancer immunotherapy.
2010
The synthesis of perfluoroalkylated glycopeptide antigens and their specific binding to anti-MUC1 mouse antibodies is reported.
Predicting stiffness and strength of birch pulp:Polylactic acid composites
2016
This paper studies failure of birch pulp–polylactic acid composites. Stiffness and strength are calculated using the theory of short fibre composites and the results are compared to experimental data. The results differed from the experimental values by 0–6%. With less aligned fibres the short fibre theory is not feasible. The performance of the 40 wt% birch pulp – polylactic acid composite is predicted with X-ray microtomography based finite element modelling, and the results are compared with experiments. Stiffness results differed from experiments by 1–17% . By adding into the models a third material phase representing the interface between the fibres and the matrix, the stress–strain c…
Hydration process and rheological properties of cement pastes modified by orthophosphate addition
2005
Abstract The use of cement by nuclear industry for confining low radioactive waste knows a constant increase. The interest bore to this material is due to its mechanical and chemical properties. However, these properties may be modified by the nature and the amount of wastes introduced with the mixing solution especially with large amount of phosphate. Precipitation of hydroxylapatite in the cement paste at the very beginning after mixing was emphasized from a particular concentration of orthophosphate. It was also found that this phenomenon leads to an early rigidification of the cement paste. From a kinetics point of view, the evolution of hydration was both delayed and slowed down accord…
Analysis and optimization of hybrid double lap aluminum-GFRP joints
2014
In this paper a systematic investigation of the mechanical performance of hybrid double-lap Al-GFRP bonded-bolted joints, has been carried out by using experimental analyses and numerical simulations. In order to detect the optimal geometric configuration, as well as to highlight the contribution of adhesive and bolts, the results relative to hybrid joints have been compared with those of simply adhesively bonded and simply bolted joints. The experimental and numerical results have shown that by using the minimum overlap length provided from theory, the bolt leads to a significant decreasing of both the maximum shear and the maximum peel stresses in the adhesive layer and, consequently, the…
The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells
2010
Abstract Earlier studies have demonstrated that biosilica, synthesized by the enzyme silicatein, induces hydroxyapatite formation in osteoblast-like SaOS-2 cells. Here we study the effect of biosilica on the expressions of osteoprotegerin [OPG] and the receptor activator for NF-κB ligand [RANKL] in the SaOS-2 cell model. We show that during growth of SaOS-2 cells on biosiliceous matrices hydroxyapatite formation is induced, while syntheses of cartilaginous proteoglycans and sulfated glycosaminoglycans are down-regulated. Furthermore, quantitative real-time RT-PCR analysis revealed a strong time-depended increase in expression of OPG in biosilica exposed SaOS-2 cells while the steady-state e…
Numerical experimental analysis of hybrid double lap aluminum-CFRP joints
2015
Abstract Due to their reliability and ease of assembly, both the adhesively bonded and the mechanical joints are commonly used in different fields of modern industrial design and manufacturing, to joint composite materials or composites with metals. As it is well known, adhesively bonded joints are characterized by high stiffness and good fatigue life, although delamination phenomena localized near the free edges may limit their use, especially for applications where corrosive environments and/or moisture can lead to premature failure of the bonding. In these cases, a possible alternative is given by the well-known mechanical joints. On the contrary, these last joints (bolted, riveted) requ…
Chromogenic detection of nerve agent mimics
2008
The current rise in international concern over criminal terrorist attacks via chemical warfare (CW) agents has resulted in an increasing interest in the detection of these lethal chemicals. Among CW species, nerve agents are extremely dangerous and their high toxicity and ease of production underscore the need to detect these deadly chemicals via quick and reliable procedures. A number of detection systems have been developed, most of them based on enzymatic and physical methodologies. However, these usually show limitations such as low selectivity, lack of portability and a certain complexity in their use. An alternative to these classical methods that has been gaining interest in recent y…
Il Museo e il territorio - Il MUCEB di Burgio
2018
Analysis of the relationship between the museological dimension of the museum institution and the socio-cultural context of the territory. The case of the Museum of Ceramics in Burgio is examined.