Search results for "CFT"

showing 10 items of 54 documents

STUDY OF SMALL MOLECULES IN THE FIGHT AGAINST NONSENSE AND SPLICING MUTATIONS THAT CAUSE CYSTIC FIBROSIS.

2023

OrganoidNonsense mutationTranslational readthroughCystic fibrosiMicrosomeCFTRTRIDSplicing mutationkinetinRECTAS
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Black holes in five-dimensional Palatinif(R)gravity and implications for the AdS/CFT correspondence

2014

We show that theories having second-order field equations in the context of higher-dimensional modified gravity are not restricted to the family of Lovelock Lagrangians, but can also be obtained if no a priori assumption on the relation between the metric and affine structures of space-time is made (the Palatini approach). We illustrate this fact by considering the case of Palatini $f(R)$ gravities in five dimensions. Our results provide an alternative avenue to explore new domains of the AdS/CFT correspondence without resorting to ad hoc quasitopological constructions.

PhysicsBlack holeGeneral Relativity and Quantum CosmologyNuclear and High Energy PhysicsAdS/CFT correspondenceGravity (chemistry)Metric (mathematics)A priori and a posteriorif(R) gravityContext (language use)Affine transformationMathematical physicsPhysical Review D
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Quantum spectral curve for arbitrary state/operator in AdS$_5$/CFT$_4$

2015

We give a derivation of quantum spectral curve (QSC) - a finite set of Riemann-Hilbert equations for exact spectrum of planar N=4 SYM theory proposed in our recent paper Phys.Rev.Lett. 112 (2014). We also generalize this construction to all local single trace operators of the theory, in contrast to the TBA-like approaches worked out only for a limited class of states. We reveal a rich algebraic and analytic structure of the QSC in terms of a so called Q-system -- a finite set of Baxter-like Q-functions. This new point of view on the finite size spectral problem is shown to be completely compatible, though in a far from trivial way, with already known exact equations (analytic Y-system/TBA, …

PhysicsHigh Energy Physics - TheoryNuclear and High Energy Physics010308 nuclear & particles physicsOperator (physics)Spectrum (functional analysis)FOS: Physical sciencesMathematical Physics (math-ph)State (functional analysis)AdS-CFT Correspondence01 natural sciencesAdS/CFT correspondenceHigh Energy Physics - Theory (hep-th)MonodromyPhysical Sciences0103 physical sciencesFysikIntegrable Field TheoriesAnti-de Sitter space010306 general physicsFinite setQuantumMathematical PhysicsMathematical physics
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Entropy function from toric geometry

2021

It has recently been claimed that a Cardy-like limit of the superconformal index of 4d $\mathcal{N}=4$ SYM accounts for the entropy function, whose Legendre transform corresponds to the entropy of the holographic dual AdS$_5$ rotating black hole. Here we study this Cardy-like limit for $\mathcal{N}=1$ toric quiver gauge theories, observing that the corresponding entropy function can be interpreted in terms of the toric data. Furthermore, for some families of models, we compute the Legendre transform of the entropy function, comparing with similar results recently discussed in the literature.

PhysicsHigh Energy Physics - TheoryNuclear and High Energy PhysicsSettore FIS/02 - Fisica Teorica Modelli E Metodi MatematiciQuiverFOS: Physical sciencesToric varietyBlack hole entropy Black hole microstates superconformal index AdS/CFTQC770-798Binary entropy functionLegendre transformationEntropy (classical thermodynamics)symbols.namesakeHigh Energy Physics - Theory (hep-th)Rotating black holeNuclear and particle physics. Atomic energy. RadioactivitysymbolsLimit (mathematics)Gauge theoryMathematical physicsNuclear Physics B
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Classical resolution of black hole singularities in arbitrary dimension

2015

A metric-affine approach is employed to study higher-dimensional modified gravity theories involving different powers and contractions of the Ricci tensor. It is shown that the field equations are \emph{always} second-order, as opposed to the standard metric approach, where this is only achieved for Lagrangians of the Lovelock type. We point out that this property might have relevant implications for the AdS/CFT correspondence in black hole scenarios. We illustrate these aspects by considering the case of Born-Infeld gravity in $d$ dimensions, where we work out exact solutions for electrovacuum configurations. Our results put forward that black hole singularities in arbitrary dimensions can…

PhysicsHigh Energy Physics - TheoryNuclear and High Energy PhysicsWhite holeFOS: Physical sciencesBlack holeGravitationAdS/CFT correspondenceTheoretical physicsGeneral Relativity and Quantum CosmologyClassical mechanicsRotating black holeHigh Energy Physics - Theory (hep-th)Extremal black holeGravitational singularityRicci curvature
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AdS$_3$ solutions with exceptional supersymmetry

2018

Among the possible superalgebras that contain the AdS$_3$ isometries, two interesting possibilities are the exceptional $F(4)$ and $G(3)$. Their R-symmetry is respectively SO(7) and $G_2$, and the amount of supersymmetry ${\cal N}=8$ and ${\cal N}=7$. We find that there exist two (locally) unique solutions in type IIA supergravity that realize these superalgebras, and we provide their analytic expressions. In both cases, the internal space is obtained by a round six-sphere fibred over an interval, with an O8-plane at one end. The R-symmetry is the symmetry group of the sphere; in the $G(3)$ case, it is broken to $G_2$ by fluxes. We also find several numerical ${\cal N}=1$ solutions with $G_…

PhysicsHigh Energy Physics - TheoryPure mathematicsSettore FIS/02 - Fisica Teorica Modelli E Metodi Matematici010308 nuclear & particles physicsInternal spaceSupergravityGeneral Physics and AstronomyFibered knotFOS: Physical sciencesSupersymmetrySymmetry groupType (model theory)SuperalgebraSupergravity01 natural sciencesHigh Energy Physics - Theory (hep-th)0103 physical sciencesInterval (graph theory)AdS/CFTSymmetry (geometry)010306 general physicsSuperalgebras AdS/CFT Supergravity
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A holographic approach to low-energy weak interactions of hadrons

2011

We apply the double-trace formalism to incorporate nonleptonic weak interactions of hadrons into holographic models of the strong interactions. We focus our attention upon $\Delta S=1$ nonleptonic kaon decays. By working with a Yang-Mills--Chern-Simons 5-dimensional action, we explicitly show how, at low energies, one recovers the $\Delta S=1$ weak chiral Lagrangian for both the anomalous and nonanomalous sectors. We provide definite predictions for the low energy coefficients in terms of the AdS metric and argue that the double-trace formalism is a 5-dimensional avatar of the Weak Deformation Model introduced long ago by Ecker et al. As a significant phenomenological application, we reasse…

PhysicsNuclear and High Energy PhysicsParticle physicsMesonmesoniinterazioni deboliHolographyFOS: Physical scienceslaw.inventionmodelli olograficisymbols.namesakeAdS/CFT correspondenceTheoretical physicsHigh Energy Physics - PhenomenologyLow energyHigh Energy Physics - Phenomenology (hep-ph)FactorizationlawsymbolsEffective actionLagrangianCounterexample
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Neutral pion production with respect to centrality and reaction plane in Au+Au collisions atsNN=200GeV

2013

The PHENIX experiment has measured the production of pi(0)s in Au + Au collisions at root S-NN = 200 GeV. The new data offer a fourfold increase in recorded luminosity, providing higher precision and a larger reach in transverse momentum, p(T), to 20 GeV/c. The production ratio of eta/pi(0) is 0.46 +/- 0.01(stat) +/- 0.05(syst), constant with p(T) and collision centrality. The observed ratio is consistent with earlier measurements, as well as with the p + p and d + Au values. pi(0) are suppressed by a factor of 5, as in earlier findings. However, with the improved statistical precision a small but significant rise of the nuclear modification factor R-AA vs p(T), with a slope of 0.0106 +/-(0…

PhysicsQuantum chromodynamicsNuclear physicsNuclear and High Energy PhysicsAdS/CFT correspondenceParticle physicsPionLuminosity (scattering theory)Path lengthConformal field theoryPartonRelativistic Heavy Ion ColliderPhysical Review C
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An overview on chemical structures as ΔF508-CFTR correctors

2019

Deletion of phenylalanine at position 508 (F508del) in the CFTR protein, is the most common mutation causing cystic fibrosis (CF). F508del causes misfolding and rapid degradation of CFTR protein a defect that can be targeted with pharmacological agents termed “correctors”. Correctors belong to various chemical classes but are generally small molecules based on nitrogen sulfur or oxygen heterocycles. The mechanism of action of correctors is generally unknown but there is experimental evidence that some of them can directly act on mutant CFTR improving folding and stability. Here we overview the characteristics of the various F508del correctors described so far to obtain indications on key ch…

Protein FoldingCystic FibrosisCFTR correctorMutantCystic Fibrosis Transmembrane Conductance RegulatorPyrimidinonesmedicine.disease_cause01 natural sciencesF508del-CFTR03 medical and health sciencesMutant proteinDrug DiscoverymedicineAnimalsHumansCFTR030304 developmental biologyPharmacology0303 health sciencesMutationCFTR correctorsbiology010405 organic chemistryChemistryOrganic ChemistryCFTR; CFTR correctors; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; F508del-CFTR; Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Mutation; Protein Folding; Pyrimidinones; ThiazolesGeneral MedicineSettore CHIM/08 - Chimica FarmaceuticaSmall moleculeCystic fibrosis transmembrane conductance regulator0104 chemical sciencesCell biologyThiazolesMechanism of actionCystic fibrosiMutationbiology.proteinmedicine.symptomProtein Aδf508 cftrEuropean Journal of Medicinal Chemistry
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Response behaviour of reinforced concrete beams strengthened in shear with FRP

2019

In this paper an analytical model, able to predict the shear-displacement response of slender RC beams reinforced in shear with FRP, is presented. It allows to evaluate the complete strain and stress fields, for each load step, on the basis of the MCFT framework. The key role of the effective strain of FRP reinforcement at failure has been investigated. At the same time, the interaction FRP-steel stirrups has been taken into account by introducing an appropriate factor. It is able to reproduce the decrease of stirrups stress level when an external reinforcement is used. The proposed model has been validate against a database of specimens collected in literature. Results have shown the remar…

RC beamShearMCFTModellingFRP
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