Search results for "CHAMBER"
showing 10 items of 359 documents
Nortriptyline hydrochloride skin absorption: development of a transdermal patch.
2007
The influence of propylen glycol (PG), ethanol, and oleic acid (OA) on nortriptyline hydrochloride (NTH) penetration through human epidermis was studied in vitro at two different pH values (5.5 and 7.4). The influence of lactic acid and polysorbate 80 was studied for a pH of 5.5. Permeation studies through Heat Separated Epidermis, as well as the enhancing effect of the different vehicles, showed a pH dependency. A pH value of 5.5 in the donor solution decreases significantly the permeability coefficient (Kp) with respect to a pH value of 7.4 (0.011+/-0.004 x 10(-6) versus 0.36+/-0.04 x 10(-6)cm/s). The vehicles showed an increasing enhancement effect in the order: polysorbate 80>ethanol/PG…
Suprachoroidal Bleeding After XEN Gel Implantation
2017
Purpose To report for the first time a clinical case of suprachoroidal bleeding after XEN45 gel implantation. Observations A 84-year old female patient with pseudoexfoliation glaucoma with intraocular pressure (IOP) (20 mm Hg) above target despite maximal IOP-lowering therapy was scheduled for XEN45 gel implantation. The XEN45 gel implantation went without complications and was properly placed in the anterior chamber and beneath the conjunctiva. On the first postoperative day, the patient presented with an IOP of 4 mm Hg, a functioning bleb and a deep anterior chamber. On the second day she developed suprachoroidal bleeding. A wait and see strategy was followed and the patient monitored ste…
Controllable Solid Rocket Motor Nozzle Operations in Conditions of Limited-Amplitude Fluctuations
2009
A nonlinear multi scale analysis of a controllable solid rocket motor operating in conditions ranging from high-amplitude fluctuations in combustion chamber to conditions lying in limit cycle is presented and the motor behavior subsequent to some relevant nozzle operations is investigated. Effects of acoustic-vorticity-entropy wave coupling, wave steepening, rotational/viscous flow losses, steep-fronted wave losses are taken into account and oscillatory energy losses in pintle-nozzle, unsteady combustion and chamber geometry changes resulting from grain regression are included. The analysis provides evidence that the unsteady energy balance and the motor wave amplitude evolution are influen…
Ozone-induced reductions in below-ground biomass: an anatomical approach in potato
2010
[EN] Potato plants were grown in open-top chambers under three ozone concentrations during two complete cropping seasons (93 and 77 d in 2004 and 2005, respectively). The effects of chronic exposure to ozone on leaf anatomy, cell ultrastructure and crop yield were studied. Severe cell damage was found, even at ambient ozone levels, mainly affecting the spongy parenchyma and areas near the stomata. Damage to the cell wall caused loss of cell contact, and loss of turgor pressure due to tonoplast disintegration, contributed to cell collapse. Phloem sieve plates were obstructed by callose accumulation, and damaged mesophyll cells increased their starch stores. Tuber yield fell sharply (24–44%),…
Radio frequency shielding of thin aluminized plastic filters investigated for the ATHENA X-IFU detector
2018
Copyright 2018 Society of Photo-Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. The X-ray Integral Field Unit (X-IFU) is one of the two detectors of the ATHENA astrophysics space mission approved by ESA in the Cosmic Vision 2015-2025 Science Programme. The X-IFU consists of a large array of transition edge sensors (TES) micro-calorimeters covering a field of view of 5' diameter, sensitive in the energy range 0.2-12 keV, and providing a spectral resolution…
La linea spezzata. Una ricostruzione critica dell'attuale deficit di coerenza
2021
Siamo nell’era della smemoratezza. Una smemoratezza prodotta dalla sovrabbondanza di informazioni, dalla pratica del multitasking, dalla propensione a demandare la conservazione dei ricordi ai device e ai cloud di cui facciamo uso ogni giorno. La fragilità della memoria ha spezzato la linea che congiungeva passato, presente e futuro, la linea che li attraversava e li rendeva coerenti. Ma lo ha fatto solo nella nostra testa, perché sul piano della realtà gli effetti delle scelte di ieri non smettono di presentarsi all’oggi. L’allargamento degli orizzonti culturali prodotto dalla globalizzazione ha ridotto tutti gli elementi del nostro panorama a dettagli lontani e indistinguibili. Ma lo ha f…
Das mehrsprachige Abgeordnetenhaus der Tschechoslowakei in seiner parlamentarischen Praxis 1920–1938
2017
The Multilingual Chamber of Deputies of Czechoslovakia in its Parliamentary Practice, 1920–1938 In addition to the two official languages of Czech and Slovak, German, Hungarian, Russian, Ukrainian, and Polish were allowed to be spoken as secondary languages in the lower house of Czechoslovakia’s parliament in 1920 in order to increase the acceptance of the new republic by the deputies of all national minorities. By swearing the oath in one of these languages, a deputy obtained the right to use this language in parliament. This article examines in which situations and how often members of parliament of minority descent took advantage of this right, regardless of their political convictions. …
Dark Matter Search Results from a One Ton-Year Exposure of XENON1T
2018
We report on a search for Weakly Interacting Massive Particles (WIMPs) using 278.8 days of data collected with the XENON1T experiment at LNGS. XENON1T utilizes a liquid xenon time projection chamber with a fiducial mass of $(1.30 \pm 0.01)$ t, resulting in a 1.0 t$\times$yr exposure. The energy region of interest, [1.4, 10.6] $\mathrm{keV_{ee}}$ ([4.9, 40.9] $\mathrm{keV_{nr}}$), exhibits an ultra-low electron recoil background rate of $(82\substack{+5 \\ -3}\textrm{ (sys)}\pm3\textrm{ (stat)})$ events/$(\mathrm{t}\times\mathrm{yr}\times\mathrm{keV_{ee}})$. No significant excess over background is found and a profile likelihood analysis parameterized in spatial and energy dimensions exclude…
Si esto es un padre
2016
E<span>n la película de László Nemes, El hijo de Saúl (2015), el protagonista encuentra a un niño agonizante que ha sobrevivido a la cámara de gas en el campo de Auschwitz-Birkenau y a quien después un médico de las SS asfixia con sus propias manos. La escena de este asesinato confronta a Saúl (Géza Röhrig) en sus límites como viviente; decide con determinación entonces que este cadáver no se sumará a la maquinaria de muerte que es el campo de exterminio y busca desesperadamente un rabino para enterrarlo. Este artículo analiza la enigmática obstinación de este personaje en relación con los límites de la vida humana que puso en juego el nazismo y con los límites visuales de la represen…
High-performance liquid chromatographic determination of sumatriptan after in vitro transdermal diffusion studies.
2004
A simple, accurate, precise and rapid HPLC method with UV detection has been validated in order to determine the in vitro transdermal absorption of sumatriptan succinate. The HPLC method is a modification of that described by Nozal et al. [M.J. Nozal, J.L. Bernal, L. Toribio, M.T. Martin, F.J. Diez, J. Pharm. Biomed. Anal. 30 (2002) 285-291]. Separation was carried out on a 250 mm Kromasil C18 column at room temperature. The detector response, at 282.7 nm, was found to be linear in a concentration range between 0.145 and 145 microM. The limit of detection (LOD) was 0.019 microM and the limit of quantification (LOQ) was 0.145 microM.