Search results for "CHIMICA"

Il fitochimico indicaxantina previene stress ossidativo, arresto del ciclo cellulare ed apoptosi indotta da 7-Ketocolesterolo in monociti-macrofagi u…

2012

PHYTOCHEMICAL INDICAXANTHIN PREVENTS 7-ketoCHOLESTEROL-INDUCED OXIDATIVE STRESS, CELL CYCLE ARREST AND APOPTOSIS IN HUMAN MONOCYTES- MACROPHAGES.

Sviluppo di metodi analitico-tossicologici per la determinazione di PCDD/F e PCB in matrice ambientale. Livelli di contaminazione per la Regione Sici…

2012

“ Hydrogeochemical study of water points and springs in Ortigia Island (Syracuse)”

2009

Gas geochemistry of shallow submarine vents in the Aegean sea (Greece)

2017

The Aegean area, which is geodynamically very active, is characterised by intense seismic activity, presence of active volcanic systems and anomalous geothermal gradients. Like other regions of intense geodynamic activity it is also characterized by extensive geogenic degassing. Gas manifestations are not only widespread on land but are also very frequent underwater. Many of these, as for example those of Milos and Santorini, are known since long time and have been previously studied although the targets were generally the hot waters or the sediments affected by the emissions (Smith and Cronan 1978, Dando et al. 1995, Price et al. 2013, Megalovassilis 2014).The present study aims at produci…

Substituent effects on the mechanism changeover in a multipathway reaction: A model for the behavior of biological systems?

2009

By studying the rearrangement in dioxane/water of a series of (Z)-arylhydrazones of 5-amino-3- benzoyl-1,2,4-oxadiazole (1a-k) into the relevant (2-aryl-5-phenyl-2H-1,2,3-triazol-4-yl)ureas (2a-k) in a wide range of pS + (an operational scale of proton concentration in the mixed solvent used; dioxane/water, 1:1, v:v), the occurrence of three different reaction pathways (specific-acid- catalyzed, uncatalyzed, and general-base-catalyzed) for the relevant SNi process has been recently enlightened. The significantly different substituent effects on the three pathways cause some crossovers in the log kA,R versus pS + plots. Both the pS + value at which the crossover occurs and the width of the u…

Sulfonamide moiety as "molecular chimera" in the design of new drugs.

2021

Background: The -SO2NH- group is of great significance in modern pharmaceutical use since, in sulfa-drugs, it is possible to introduce easily chemical modifications, and even small changes may lead to an improved version of an already existing drug. Objective: This paper aims to describe updated information in the sulfonamide field with a particular focus on new mechanisms of action, especially if discovered by employing computational approaches. Methods: Research articles that focused on the use of the sulfonamide moiety for the design, synthesis, and in vitro/in vivo tests of various diseases were collected from various search engines like PubMed, Science Direct, Google Scholar, and Scop…

SOSTENIBILITÀ E RESILIENZA DELL’AGRICOLTURA DOPO LA PANDEMIA COVID-19

2020

1. Introduzione. – 2. Agenda 2030 ONU sviluppo sostenibile. – 3. Misure restrittive del COVID-19 e impatto sul mercato dei lavoratori agricoli. – 4. Etica della utilizzazione del suolo: agricoltura biologica, agricoltura urbana, permacoltura. – 5. Le funzioni ecosistemiche del suolo dopo il COVID-19. – 6. La salvaguardia del suolo per mitigare i cambiamenti climatici. – 7. La degradazione del suolo e la sicurezza alimentare. – 8. Prospettive dell’agricoltura italiana dopo il COVID-19.

A one-pot method to enhance dissolution rate of low solubility drug molecules using dispersion polymerization in supercritical carbon dioxide

2009

Melt phase ring opening polymrization of lactide and glycolide assisted by supercritical carbon dioxide

2010

Polystyrene-supported organocatalysts for alfa-selenenylation and Michael reactions. A common post-modification approach for catalytic differentiation

2011

Three different resin-supported catalysts have been prepared by using the well established post-modification approach by means of thiol-ene coupling reaction. Two catalysts were tested for the first time in the asymmetric α-selenenylation of propanal, while the third catalyst was used in the Michael addition reaction. While the preliminary results are not encouraging in the case of supported Jørgensen’ catalyst, interesting data have been collected with both for the supported MacMillan and prolyl-prolinol catalysts. In fact, these catalysts displayed good activity and selectivity. A reversed enantioselectivity in the α-selenenylation was observed by changing the polarity of the solvent. Fin…