Search results for "CHIMIE"
showing 10 items of 170 documents
Microlensing Discovery of a Population of Very Tight, Very Low Mass Binary Brown Dwarfs
2013
Although many models have been proposed, the physical mechanisms responsible for the formation of low-mass brown dwarfs (BDs) are poorly understood. The multiplicity properties and minimum mass of the BD mass function provide critical empirical diagnostics of these mechanisms. We present the discovery via gravitational microlensing of two very low mass, very tight binary systems. These binaries have directly and precisely measured total system masses of 0.025 M [SUB]⊙[/SUB] and 0.034 M [SUB]⊙[/SUB], and projected separations of 0.31 AU and 0.19 AU, making them the lowest-mass and tightest field BD binaries known. The discovery of a population of such binaries indicates that BD binaries can …
Analysis of the structural quality of the CASD-NMR 2013 entries
2015
We performed a comprehensive structure validation of both automated and manually generated structures of the 10 targets of the CASD-NMR-2013 effort. We established that automated structure determination protocols are capable of reliably producing structures of comparable accuracy and quality to those generated by a skilled researcher, at least for small, single domain proteins such as the ten targets tested. The most robust results appear to be obtained when NOESY peak lists are used either as the primary input data or to augment chemical shift data without the need to manually filter such lists. A detailed analysis of the long-range NOE restraints generated by the different programs from t…
Connectivity percolation in suspensions of hard platelets
2012
We present a study on connectivity percolation in suspensions of hard platelets by means of Monte Carlo simulation. We interpret our results using a contact-volume argument based on an effective single--particle cell model. It is commonly assumed that the percolation threshold of anisotropic objects scales as their inverse aspect ratio. While this rule has been shown to hold for rod-like particles, we find that for hard plate-like particles the percolation threshold is non-monotonic in the aspect ratio. It exhibits a shallow minimum at intermediate aspect ratios and then saturates to a constant value. This effect is caused by the isotropic-nematic transition pre-empting the percolation tran…
The sedimentary series of upper Bajocian-lower Bathonian age and their organization in the Burgundy threshold and its surroundings. Stratigraphy, sed…
1981
Three fundamental features concerning the organization of the bio-sedimentary series of the upper Bajocian-lower Bathonian of the Burgundy threshold environment are retained:- the formations are organized in a bio-sedimentary platform, composed of three sets: a deep SW platform with clay sedimentation, a superficial NE platform, a transition zone- the geochemical characteristics are consistent with the reconstitution of the NE-NW polarized platform- this device has changed over time: a migration and extension of the surface platform to the SW, development of the transition zone, a slight displacement of the deep platform correlated with a more and more opening towards the SW.
Milk-blood transfer of C-14-tagged polycyclic aromatic hydrocarbons (PAHs) in pigs
2001
International audience
Changements climatiques et océanographiques au cours du Campanien – approche couplée minéralogie et géochimie
2018
The origin of the Late Cretaceous (~100 – 65 Ma) global cooling is not yet well understood. The evolution of sea surface and bottom temperatures shows an acceleration of the cooling during the Campanian stage (~84 Ma). The main goal of this study was to explore the processes driving this cooling, focusing on Campanian sediments from the Tethyan, Boreal and Atlantic realms.The clay mineralogical assemblages of several (hemi)pelagic sites, selected along a S-N transect, from 5° to 45°N, reveal an increase in continental weathering during the Campanian, expressed by enhanced kaolinite inputs. The detrital input related to the uplift of new continental areas seems to evolve from south to north.…
Isotropic-nematic interface in suspensions of hard rods: Mean-field properties and capillary waves
2006
We present a study of the isotropic-nematic interface in a system of hard spherocylinders. First we compare results from Monte Carlo simulations and Onsager density functional theory for the interfacial profiles of the orientational order parameter and the density. Those interfacial properties that are not affected by capillary waves are in good agreement, despite the fact that Onsager theory overestimates the coexistence densities. Then we show results of a Monte Carlo study of the capillary waves of the interface. In agreement with recent theoretical investigations (Eur.Phys.J. E {\bf 18} 407 (2005)) we find a strongly anistropic capillary wave spectrum. For the wave-numbers accessed in o…
Study of the role of the CDC48 chaperone protein in plant immunity
2018
The chaperone protein CDC48 (Cell division cycle 48) is a major regulator of the quality control of proteins and is involved in various cellular processes in animals and yeast. In contrast, the role of CDC48 in plants is poorly known. In the present work, we investigated the function of CDC48 in plant immunity thanks to the cryptogein/tobacco biological model, cryptogein being produced by the oomycete phytophthora cryptogea.Three strategies were carried out. First, the dynamic of accumulation CDC48 together with intracellular events inherent to the immune response were analyzed in both wild-type and CDC48 overexpressing tobacco cells (CDC48-TAP line). Second, a list if CDC48 partners was es…
Etude du rôle de la protéine CDC48 dans l'immunité des plantes
2018
The chaperone protein CDC48 (Cell division cycle 48) is a major regulator of the quality control of proteins and is involved in various cellular processes in animals and yeast. In contrast, the role of CDC48 in plants is poorly known. In the present work, we investigated the function of CDC48 in plant immunity thanks to the cryptogein/tobacco biological model, cryptogein being produced by the oomycete phytophthora cryptogea.Three strategies were carried out. First, the dynamic of accumulation CDC48 together with intracellular events inherent to the immune response were analyzed in both wild-type and CDC48 overexpressing tobacco cells (CDC48-TAP line). Second, a list if CDC48 partners was es…
Amperometric detection of extended-spectrum β-lactamase activity : application to the characterization of resistant E.coli strains
2015
EA MERS CT3; International audience; The amperometric detection of extended-spectrum β-lactamase (ESBL) with carbon screen-printed sensors was investigated in the presence of the Nitrocefin, a commercially-available β-lactamase chromogenic cephalosporin substrate. Using an ESBL isolated from a clinical sample, it was shown for the first time that the intensity of a specific anodic pic current (EP = [similar]+0.3 V vs. Ag/AgCl) resulting from the catalytic hydrolysis of the β-lactam ring was proportional to the amount of ESBL. The proof-of-principle of a novel susceptibility assay for the rapid and accurate identification of ESBL- producing bacteria was then demonstrated. The detection schem…