Search results for "CHOLESTÉROL-24S-HYDROXYLASE"

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Cholestérol-24S-hydroxylase (CYP46A1) et homéostasie du cholestérol dans la rétine en conditions physiologiques et pathologiques

2012

Cholesterol is the major sterol found in the retina. In its free form, cholesterol is present in all cell layers of the retina, whereas cholesteryl esters mainly accumulate at the basement of the retinal pigment epithelium. The intrinsic capacity of the retina to synthetize cholesterol appears limited. Some extra-retinal pathways actively participate to cholesterol uptake to the retina. Müller glial cells may contribute to cholesterol supply to retinal neurons, especially for synaptic formation. Cholesterol accumulation or conversely deficiency have deleterious consequences on neuron survival. Maintaining the equilibrium between cholesterol supply and neosynthesis in the one hand and choles…

[SDV.SA]Life Sciences [q-bio]/Agricultural sciencesRétinePolymorphisme génétique24S-HYDROXYCHOLESTÉROLRetinaCHOLESTÉROL-24S-HYDROXYLASE24S-hydroxycholesterolMétabolisme[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyGliaPathologyGlieCholesterol-24S-hydroxylase[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciences[SDV.SA] Life Sciences [q-bio]/Agricultural sciencesPathologie[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyDégénérescence maculaire liée à l’âgeCHOLESTEROLAge-related macular degenerationGene polymorphismGlaucomaNeuronGlaucome[SDV.AEN] Life Sciences [q-bio]/Food and NutritionCYP46A1MetabolismCholestérol[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyNeurone

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PEPhysical Sciences and Engineering
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