Search results for "CHON"

El carácter transdiagnóstico de las intrusiones mentales/ Transdiagnostic nature of unwanted mental intrusions

2019

Unwanted mental intrusions (UMIs) and their functional consequences had been proposed as symptom dimensions in current cognitive models of Obsessive-Compulsive Disorder (OCD), Body Dysmorphic Disorder (BDD), Illness Anxiety/Hypochondriasis (IA/H) and Eating Disorders (EDs). The main purpose of this doctoral dissertation was to ascertain the transdiagnostic nature of UMIs, above and beyond their specific contents, i.e., obsessional, appearance defects, illness and death, and eating disorders-related. To this end, the Questionnaire of Unpleasant Intrusive Thoughts (QUIT) was designed, and, based on it, four studies were conducted. Studies 1 and 2 examined the transdiagnostic nature of UMIs, b…

Observation macroscopique de terres cuites architecturales du site de Brochon

2011

Randomized Trial : D-Glyceric Acid Activates Mitochondrial Metabolism in 50–60-Year-Old Healthy Humans

2021

Background: Based on earlier studies, natural metabolite D-glyceric acid (DGA) does not seem to play any role in whole-body metabolism. Nevertheless, one ethanol oxidation-related rat study with controversial results raised our interest. According to preparatory studies for the regulatory approval of DGA, some highly conserved mechanism seems to subtly activate the cellular energy metabolism. Therefore, the present 25-days double-blind human study with placebo control was initiated. Purpose: The main target in the present study with 27 healthy 50–60-year-old human volunteers was to find out whether an “acute” 4-days and a longer 21-days exogenous DGA regimen caused moderate activation of th…

Real-world experience with obeticholic acid in patients with primary biliary cholangitis

2021

Background & aims Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety of OCA under real-world conditions. Methods Patients were recruited into the Italian PBC Registry, a multicentre, observational cohort study that monitors patients with PBC at national level. The primary endpoint was the biochemical response according to Poise criteria; the secondary endpoint was the biochemical response according to normal range criteria, defined as normal levels of bilirubin, alkaline phosphatase (ALP), and alanine aminotransfer…

Virus-cell interactions as a pathological mechanism of parvovirus infection

2014

Agronomical evaluation of Sicilian biotypes of Lavandula stoechas L. spp. stoechas and analysis of the essential oils

2015

The aim of this study was to characterize wild lavender, which was collected in three different areas of Sicily (Italy),according to agronomic and chemical evaluation. The collection sites were located in Pantelleria island, Partinico (a warm sub-area of Lauretum) and Castelbuono (a middle sub-area of Lauretum). All the populations were identified as Lavandula stoechas L. ssp. stoechas. Essential oils were extracted by hydrodistillation and analyzed by gas chromatography– flame ionization detector (GC–FID) and GC–mass spectrometry (GC–MS). GC–FID and GC–MS analyses permitted the identification of 101 components from the essential oils. We analyzed only the flowers and leaves of L. stoechas …