Search results for "CID"
showing 10 items of 19479 documents
Análisis de procesos inmunorreguladores en helmintiasis intestinales mediante el modelo Echinostoma caproni-ratón
2021
En la presente Tesis Doctoral se analizan diferentes parámetros que intervienen en las interacciones parásito-hospedador en helmintiasis intestinales mediante el empleo del modelo experimental Echinostoma caproni-ratón ICR. Para ello, se realizan diferentes estudios en los que se analiza y compara la respuesta inmunitaria en infecciones primarias, asociadas a susceptibilidad, y secundarias, asociadas a resistencia. Los resultados obtenidos demuestran que la susceptibilidad del ratón a la infección primaria con E. caproni se debe a su incapacidad de responder con producción de IL-25 lo cual determina que se genere una respuesta Th1 asociada a susceptibilidad. Asimismo, estos resultados ponen…
Synthesis and characterization of a new set of protic ionic liquids
2012
Interaction of mushroom tyrosinase with aromatic amines, o-diamines and o-aminophenols
2004
3-Amino-L-tyrosine was found to be a substrate of mushroom tyrosinase, contrary to what had previously been reported in the literature. A series of amino derivatives of benzoic acid were tested as substrates and inhibitors of the enzyme. 3-Amino-4-hydroxybenzoic acid, 4-amino-3-hydroxybenzoic acid and 3,4-diaminobenzoic acid were oxidized by this enzyme, as previously reported for Neurospora crassa tyrosinase, but 4-aminobenzoic acid and 3-aminobenzoic acid were not. Interestingly, 3-amino-4-hydroxybenzoic acid was oxidized five times faster than 4-amino-3-hydroxybenzoic acid, confirming the importance of proton transfer from the hydroxyl group at C-4 position. All compounds inhibited the m…
Exploring fast proton transfer events associated with lateral proton diffusion on the surface of membranes
2019
Proton diffusion (PD) across biological membranes is a fundamental process in many biological systems, and much experimental and theoretical effort has been employed for deciphering it. Here, we report on a spectroscopic probe, which can be tightly tethered to the membrane, for following fast (nanosecond) proton transfer events on the surface of membranes. Our probe is composed of a photoacid that serves as our light-induced proton source for the initiation of the PD process. We use our probe to follow PD, and its pH dependence, on the surface of lipid vesicles composed of a zwitterionic headgroup, a negative headgroup, a headgroup that is composed only from the negative phosphate group, or…
Legittima difesa, tirannicidio e strategia difensiva nell’orazione di Cicerone a favore di Milone
2013
This paper presents a new analysis of the speech delivered by Cicero on behalf of Milo (pro Milone), who had been charged with the murder of Clodius. It suggests that Cicero’s defensive strategy aimed from the beginning to get an acquittal on two different grounds. The first one was based on the reasoning that Clodius’ murder was committed lawfully in self-defense. The second one was based on the argument that Clodius’ killing was in the best interest of the state. Both do not have to be conflicting. Even if the spoken version of the speech achieved just the first aim, the second aim, prevented by the interruption of Cicero’s speech due to the screams of the Clodian mob present at the trial…
Hacer espacios en patrimonialización. Prácticas cotidianas en la formación del 'Paisaje Cultural Cafetero' de Colombia - Patrimonio Mundial
2017
Esta tesis analiza la patrimonialización del ‘Paisaje Cultural Cafetero’ de Colombia, inscrito en la Lista de Patrimonio Mundial desde 2011. Se refiere a un contexto rural andino especializado en la producción de café, donde la pequeña agricultura ha perdido rentabilidad económica tras la liberalización del mercado. El patrimonio paisajístico se proyecta allí como medida de conservación, revitalización económica y pacificación. La investigación se pregunta por el efecto cotidiano de este patrimonio, diseñado en nombre de pequeños agricultores. Plantea un seguimiento etnográfico a las prácticas de productivas de café, durante los cinco años posteriores al reconocimiento de la UNESCO (2011-20…
Auteurs du site web Réseau de Réflexion et de Recherche sur la Résistance aux Pesticides (R4P) www.r4p-inra.fr
2018
Réseau de Réflexion et de Recherche sur la Résistance aux Pesticides (R4P) : www.r4p-inra.frCe site met à disposition des outils et des informations sur la résistance aux produits de protection des plantes. Ces informations peuvent intéresser les professionnels impliqués dans la prévention et la gestion des résistances, des enseignants ou étudiants, et quiconque intéressé par cette thématique.Ring for Research and Reflection on Resistance to Pesticides (R4P) :www.r4p-inra.frThis site provides tools and information on resistance to plant protection products. This information may be of interest to professionals involved in the prevention and management of resistance, teachers or students, and…
Alimentation et vision
2016
Micronutrition : de la théorie à l'application en clinique
2010
National audience; Les prévisions démographiques s'attendent à un accroissement important de la population âgée et très âgée dans les décennies à venir. La prévalence des pathologies oculaires occupe la deuxième place dans cette frange de la population, laissant entrevoir une réelle explosion du coût social et économique associé à la prise en charge des patients. Pourtant, des données théoriques suggèrent que certains nutriments, en particulier lipophiles, pourraient participer à prévenir les effets du vieillissement sur la rétine et le développement pathologique. Ces hypothèses sont corroborées par des données épidémiologiques qui renforcent l'association entre la consommation d'acides gra…
Role of the support and pseudo-liquid phase in the Phosphotungstic Heteropolyacid (photo)catalytic activity
2016
Catalytic and photocatalytic tests for propene hydration to 2-propanol were successfully carried out by using binary materials obtained by supporting a Keggin or Wells-Dawson heteropolyacids via impregnation method to commercial SiO2 or TiO2. (Photo)catalytic hydration was studied in gas-solid regime by using a continuous (photo)reactor working at atmospheric pressure and 80 °C. The alcohol was the main product. The acidity of the cluster accounts for the catalytic role, whereas both the acidity of the cluster and the oxidant ability were responsible for the increase of the reaction rate of the photo-assisted catalytic reaction. Moreover, the presence of a photoactive semiconductor support …