Search results for "CID"
showing 10 items of 19479 documents
Western Australian students' alcohol consumption and expenditure intentions for Schoolies.
2016
In Australia, the immediate post-school period (known as ‘Schoolies’) is associated with heavy drinking and high levels of alcohol-related harm. This study investigated students’ intended alcohol consumption during Schoolies to inform interventions to reduce alcohol-related harm among this group. An online survey was administered to students in their senior year of schooling. Included items related to intended daily alcohol consumption during Schoolies, amount of money intended to be spent on alcohol over the Schoolies period, and past drinking behaviour. On average, participants (n=187) anticipated that they would consume eight standard drinks per day, which is substantially higher than t…
Effects of Zoledronic Acid on Cathepsin K circulating levels in patients with bone metastasis.
2007
Cathepsin K serum levels were determinated in patients with bone metastases from breast cancer or prostate cancer in therapy with zoledronic acid or in patients or in patients with located breast or prostate cancer end in patients with non malignant diseases and in healthy blood. donors (control group). Cathepsin K serum levels were significantly more eleved in healthy subjects or in patients with peimary osteoporosis. Furthermore, the administration of Zoledronic acid to patients with metastatic bome disease from breast or prostate cancer, induced a marked increase of Cathepsin K serum levels.
Analysis of molecular mechanisms and anti-tumoral effects of zoledronic acid in breast cancer cells
2012
Background: Zoledronic acid (ZOL) is the most potent nitrogen-containing bisphosphonate (N-BPs) that strongly binds to bone mineral and acts as a powerful inhibitor of bone resorption, already clinically available for the treatment of patients with osteolytic metastases. Recent data also suggest that ZOL, used in breast cancer, may provide more than just supportive care modifying the course of the disease, though the possible molecular mechanism of action is still unclear. Aims: Since breast cancer is one of the primary tumors with high propensity to metastasize to the bone, we investigated, for the first time, differential gene expression profile on MCF-7 breast cancer cells treated with l…
Osteonecrosis of the jaw as an adverse bisphosphonate event: Three cases of bone metastatic prostate cancer patients treated with zoledronic acid
2007
Bisphosphonates offer a significant improvement in the quality of life for cancer patients; these potent inhibitors of bone resorption have been shown to markedly reduce the morbidity frequently resulting from bone metastases. Despite the success of bisphosphonates as therapeutic agents, however, toxicity in the form of osteonecrosis of the jaw (ONJ) is a rare complication whose incidence rate has climbed in recent years. ONJ is defined as an unexpected development of necrotic bone in the oral cavity, and is commonly associated with administration of the bisphosphonates Pamidronate and Zoledronate. Clinical features include local pain, soft-tissue swelling, and/or loose teeth; ONJ is also o…
Terrestrial carbohydrates support freshwater zooplankton during phytoplankton deficiency
2016
Article
Inferring phytoplankton community composition with a fatty acid mixing model
2015
Abstract. The taxon specificity of fatty acid composition in algal classes suggests that fatty acids could be used as chemotaxonomic markers for phytoplankton composition. The applicability of phospholipid-derived fatty acids as chemotaxonomic markers for phytoplankton composition was evaluated by using a Bayesian fatty acid-based mixing model. Fatty acid profiles from monocultures of chlorophytes, cyanobacteria, diatoms, euglenoids, dinoflagellates, raphidophyte, cryptophytes and chrysophytes were used as a reference library to infer phytoplankton community composition in five moderately humic, large boreal lakes in three different seasons (spring, summer and fall). The phytoplankton commu…
Caracterización fisiológica, bioquímica y molecular de nuevas variedades de naranja de pulpa roja
2023
El objetivo principal de esta Tesis Doctoral ha sido caracterizar en profundidad los frutos de dos nuevas mutaciones de naranja dulce de pulpa roja, denominados Kirkwood Navel y Ruby Valencia, procedentes de las naranjas Washington Navel (cv. Palmer) y Valencia late (cv. Olinda), respectivamente. Para ello, se abordaron las bases fisiológicas y moleculares del metabolismo de carotenoides implicadas en la singular coloración del fruto, la evolución de los componentes de calidad de los frutos durante la maduración, su aptitud para la conservación postcosecha y comercialización en fresco, y el potencial de estas nuevas variedades para la producción y procesado de zumo. Los resultados bioquímic…
CCDC 1917751: Experimental Crystal Structure Determination
2019
Related Article: Víctor García-López, Mario Palacios-Corella, Verónica Gironés-Pérez, Carlos Bartual-Murgui, José Antonio Real, Eric Pellegrin, Javier Herrero-Martín, Guillem Aromí, Miguel Clemente-León, Eugenio Coronado|2019|Inorg.Chem.|58|12199|doi:10.1021/acs.inorgchem.9b01526
Multimodalidad e innovación metodológica en la enseñanza del inglés [Recurso electrónico] : el álbum ilustrado como recurso literario y visual para e…
2020
Referencias bibliográficas: p. 74-77. Este artículo se centra en el proyecto de innovación Recursos multimodales y literacidad (UV-SFPIE_GER18-952026) llevado a cabo en la Facultat de Magisteri de la Universitat de València durante los cursos 2017-18 y 2018-19. En consonancia con los retos de la sociedad digital del siglo XXI y con el enfoque de la pedagogía de las multiliteracidades para el desarrollo del conocimiento, proponemos la multimodalidad, y en especial, el álbum ilustrado, primero, como un recurso literario y estético clave para la formación integral de los futuros docentes de inglés como L2 y, segundo, como una plataforma interdisciplinar para la construcción de significados. …