Search results for "CIS"

showing 10 items of 10697 documents

Neuromuscular adaptations during bilateral versus unilateral strength training in middle-aged and elderly men and women.

1996

Twelve middle-aged men and 12 middle-aged women in the 50-year-old age group (M50; range 44-57 years; W50; 43-57), and 12 elderly men and 12 elderly women in the 70-year-old age group (M70; 59-75; W70; 62-75) volunteered as subjects in order to examine effects of 12-week progressive heavy resistance strength training on electromyographic activity (EMG), muscle cross-sectional area (CSA) of the quadriceps femoris and maximal concentric force in a one repetition maximum (1 RM) test of the knee extensor muscles. One half of the subjects in each group performed the knee extension (and flexion) exercises only bilaterally (BIL), while another half performed the exercises only unilaterally (UNIL).…

AdultMalemedicine.medical_specialtyFunctional trainingTime FactorsPhysiologyStrength trainingElectromyographyFunctional LateralityMuscle hypertrophyOne-repetition maximumMedicineHumansExercise physiologyMuscle SkeletalExerciseAgedControl periodKnee extensorsmedicine.diagnostic_testbusiness.industryElectromyographyMiddle AgedPhysical FitnessAnesthesiaPhysical therapyBody CompositionFemalebusinessMuscle ContractionActa physiologica Scandinavica
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Mechanical step variability during treadmill running.

1995

The present study was designed to study intra-individual step variability measured both on vertical displacement of the body (delta Z) and on step time (delta t) parameters by means of a kinematic arm and during treadmill running. A group of 17 subjects ran successively at 60%, 80%, 100% and 140% of their maximal aerobic velocity (Vamax). The total number of steps analysed was 6116. The absolute delta Z step variability (sigma delta Z) ranged between 5 mm and 21 mm while the absolute delta t variability (sigma delta t) ranged between 6 ms and 40 ms. Step variabilities were due to step asymmetry (from 38.5% to 48.5% of the step variability) and to stride variability. For submaximal velocitie…

AdultMalemedicine.medical_specialtyFuture studiesPhysiologyPhysical ExertionEnergetic costSTRIDEKinematicsRunningTreadmill runningPhysiology (medical)StatisticsmedicineHumansOrthopedics and Sports MedicineVertical displacementMathematicsMean valuePublic Health Environmental and Occupational HealthGeneral MedicineOxygenData Interpretation StatisticalEnergy costPhysical therapyExercise TestEnergy MetabolismEuropean journal of applied physiology and occupational physiology
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Surgical treatment of primary gastrointestinal stromal tumors (GISTs): Management and prognostic role of R1 resections

2020

Abstract Background Surgery represents the best treatment for primary gastrointestinal stromal tumors (GISTs). The aim of this study is to analyse outcomes of surgical management in order to evaluate the influence of microscopically R1 margins on survival and recurrence in patients affected by GISTs. Methods The study reviewed retrospective data from 74 patients surgically treated for primary GISTs without metastasis at diagnosis. Clinical and pathological findings, surgical procedures, information about follow up and outcomes were analyzed. Results Recurrence rate was low and no patients died in the R1 group during the follow up period. The difference in recurrence free survival for patien…

AdultMalemedicine.medical_specialtyGastrointestinal Stromal TumorsPrognosiMetastasisPositive microscopic margins03 medical and health sciences0302 clinical medicineHumansMedicineIn patientGastrointestinal stromal tumors (GISTs)Surgical treatmentPathologicalGISTsAgedRetrospective StudiesAged 80 and overGiSTbusiness.industryMargins of ExcisionGeneral MedicineMiddle AgedSurgical proceduresPrognosismedicine.diseaseSurgeryLog-rank test030220 oncology & carcinogenesisFemale030211 gastroenterology & hepatologySurgeryNeoplasm Recurrence LocalPositive microscopic marginbusinessGISTThe American Journal of Surgery
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The effects of amino acid supplementation on hormonal responses to resistance training overreaching.

2005

The purpose of this investigation was to examine the effects of amino acid supplementation on muscular performance and resting hormone concentrations during resistance training overreaching. Seventeen resistance-trained men were randomly assigned to either an amino acid (AA) or a placebo (P) group and underwent 4 weeks of total-body resistance training designed to induce a state of overreaching. The protocol consisted of two 2-week phases (phase 1, 3 sets of 8 exercises performed for 8-12 repetitions; phase 2, 5 sets of 5 exercises performed for 3-5 repetitions). Muscle strength and resting blood samples were determined before (T1) and at the end of each training week (T2-T5). One-repetitio…

AdultMalemedicine.medical_specialtyGlobulinAnabolismHydrocortisoneEndocrinology Diabetes and MetabolismBench presschemistry.chemical_compoundHemoglobinsEndocrinologyDouble-Blind MethodInternal medicineSex Hormone-Binding GlobulinmedicineHumansTestosteroneAmino AcidsInsulin-Like Growth Factor ICreatine KinaseTestosteroneExercise TolerancebiologyHuman Growth HormoneOverreachingHormonesPeptide FragmentsUric AcidEndocrinologychemistryDietary Supplementsbiology.proteinUric acidCreatine kinaseHormoneMetabolism: clinical and experimental
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Plantarflexor muscle function in healthy and chronic Achilles tendon pain subjects evaluated by the use of EMG and PET imaging

2014

article i nfo Article history: Received 14 October 2013 Accepted 11 March 2014 18 F)-Fluorodeoxyglucose Background: Achilles tendon pathologies may alter the coordinative strategies of synergistic calf muscles. We hypothesized that both surface electromyography and positron emission tomography would reveal differences between symptomatic and asymptomatic legs in Achilles tendinopathy patients and between healthy controls. Methods: Eleven subjects with unilateral chronic Achilles tendon pain (28 years) and eleven matched controls (28 years) were studied for triceps surae and flexor hallucis longus muscle activity in response to repetitive iso- metric plantarflexion tasks performed at 30% of …

AdultMalemedicine.medical_specialtyGlucose uptakeBiophysicsElectromyographyAchilles TendonAsymptomaticYoung AdultIsometric ContractionmedicineHumansOrthopedics and Sports MedicineMuscle Skeletalta315LegAchilles tendonmedicine.diagnostic_testElectromyographybusiness.industryta1184BiomechanicsMyalgiamedicine.diseaseSurgerybody regionsGlucosemedicine.anatomical_structurePositron emission tomographyCase-Control StudiesPositron-Emission TomographyAnesthesiaTendinopathyFemaleFlexor hallucis longus muscleTendinopathymedicine.symptombusinessClinical Biomechanics
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Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival…

2015

Summary Background We aimed to assess the effect of afatinib on overall survival of patients with EGFR mutation-positive lung adenocarcinoma through an analysis of data from two open-label, randomised, phase 3 trials. Methods Previously untreated patients with EGFR mutation-positive stage IIIB or IV lung adenocarcinoma were enrolled in LUX-Lung 3 (n=345) and LUX-Lung 6 (n=364). These patients were randomly assigned in a 2:1 ratio to receive afatinib or chemotherapy (pemetrexed-cisplatin [LUX-Lung 3] or gemcitabine-cisplatin [LUX-Lung 6]), stratified by EGFR mutation (exon 19 deletion [del19], Leu858Arg, or other) and ethnic origin (LUX-Lung 3 only). We planned analyses of mature overall sur…

AdultMalemedicine.medical_specialtyGuanineLung NeoplasmsAfatinibPopulationMedizinPemetrexedNeutropeniaAdenocarcinomaAfatinibGastroenterologyDeoxycytidineGlutamatesInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineMucositisHumansRociletinibeducationLung cancerSurvival rateAgedNeoplasm StagingAged 80 and overeducation.field_of_studybusiness.industryMiddle Agedmedicine.diseasePrognosisGemcitabineSurgeryErbB ReceptorsSurvival RatePemetrexedOncologyMutationQuinazolinesFemaleCisplatinbusinessmedicine.drugFollow-Up StudiesThe Lancet. Oncology
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Region-dependent hamstrings activity in Nordic hamstring exercise and stiff-leg deadlift defined with high-density electromyography

2018

Recent studies suggest region-specific metabolic activity in hamstring muscles during injury prevention exercises, but the neural representation of this phenomenon is unknown. The aim of this study was to examine whether regional differences are evident in the activity of biceps femoris long head (BFlh) and semitendinosus (ST) muscles during two common injury prevention exercises. Twelve male participants without a history of hamstring injury performed the Nordic hamstring exercise (NHE) and stiff-leg deadlift (SDL) while BFlh and ST activities were recorded with high-density electromyography (HD-EMG). Normalized activity was calculated from the distal, middle, and proximal regions in the e…

AdultMalemedicine.medical_specialtyHamstring musclesFuture studiesQP301.H75_Physiology._Sport.High densityPhysical Therapy Sports Therapy and RehabilitationHamstring MusclesElectromyographyBiceps03 medical and health sciencesYoung Adultelectrical activity0302 clinical medicinemedicineEccentricHumansOrthopedics and Sports Medicineta315ExercisevoimanostoHamstring injurymedicine.diagnostic_testlihasaktiivisuusbusiness.industryElectromyographymuscle functionreidet030229 sport sciencesmedicine.diseasebi-articular hamstringsQPAthletic InjuriesPhysical therapyExercise Testvoimaharjoittelubusiness030217 neurology & neurosurgeryHamstringScandinavian Journal of Medicine and Science in Sports
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Exercise with TENS does not augment gains in balance and strength for dancers

2020

Abstract Electrical stimulation modulates sensory feedback and improves motor performance, at least for individuals with compromised sensorimotor function. The purpose of this study was to determine the effectiveness of a 4-wk intervention with transcutaneous electrical nerve stimulation (TENS) at improving strength and balance in dancers. Nineteen dancers completed a timed, single-leg balance test, the Y-balance test, and contractions with the hip flexor and knee extensor muscles to assess maximal strength and force steadiness. They completed 4-wks of moderate-intensity bodyweight exercises (3x/wk) and were pseudo-randomized to either a Treatment or Sham group in a single-blind design. The…

AdultMalemedicine.medical_specialtyHamstring musclesKnee JointBiophysicsNeuroscience (miscellaneous)StimulationBodyweight exerciseTranscutaneous electrical nerve stimulationlaw.inventionSham groupRandom Allocation03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationlawMaximal strengthHumansMedicineSingle-Blind MethodMuscle StrengthDancingMuscle SkeletalPostural BalanceBalance (ability)Knee extensorsbusiness.industry030229 sport sciencesExercise TherapyElectrical stimulationTranscutaneous Electric Nerve StimulationY-balance testFemaleNeurology (clinical)AugmentbusinessSingle-leg balance030217 neurology & neurosurgeryJournal of Electromyography and Kinesiology
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Investigating Risk Factors for Internet Gaming Disorder: A Comparison of Patients with Addictive Gaming, Pathological Gamblers and Healthy Controls r…

2013

Engaging in online games has become increasingly important as a part of leisure activity in adolescents and adults. While the majority of people use these games in a healthy way, epidemiological studies show that some develop excessive use and symptoms that are related to those of substance-related addictions. Despite increasing research concerning the epidemiology of internet gaming disorder (IGD), predisposing factors have been examined to a lesser extent. Knowing about specific risk factors would help clarify the nosological features of IGD and enhance prevention and intervention. This study aimed to evaluate the relationships between personality traits and IGD. A total of 115 patients m…

AdultMalemedicine.medical_specialtyHealth (social science)AdolescentPersonality Inventorymedia_common.quotation_subjectmedicine.medical_treatmentMedicine (miscellaneous)Young AdultRisk FactorsmedicinePsychoeducationHumansPersonalityBig Five personality traitsPsychiatrymedia_commonInternetExtraversion and introversionConscientiousnessmedicine.diseaseNeuroticismBehavior AddictivePsychiatry and Mental healthVideo GamesCase-Control StudiesGamblingPersonality Assessment InventoryAddictive behaviorPsychologyPersonalityClinical psychologyEuropean Addiction Research
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Association Between Physical Activity and Odds of Chronic Conditions Among Workers in Spain

2020

Introduction:\ud \ud Prevention of chronic conditions is a major public health challenge, and achieving minimum recommended levels of physical activity aids in reaching this objective. The aim of our study was to investigate whether levels of physical activity were associated with the prevalence of common chronic conditions among the Spanish workforce.\ud \ud Methods:\ud \ud We retrieved data from the Spanish National Health Survey 2017 (N = 9,695) in which the mean age of participants was 44.4 (standard deviation, 10.4 y), and 47.4% were women. Workers self-reported a set of 6 chronic conditions (ie, chronic low-back pain, chronic neck pain, diabetes, hypertension, depression, and anxiety)…

AdultMalemedicine.medical_specialtyHealth StatusLogistic regression01 natural sciencesOddsBody Mass Index03 medical and health sciences0302 clinical medicineDiabetes mellitusmedicineOdds RatioPrevalenceHumans030212 general & internal medicine0101 mathematicsExerciseDepression (differential diagnoses)Original Researchbusiness.industryHealth PolicyPublic health010102 general mathematicsPublic Health Environmental and Occupational HealthOdds ratioMiddle Agedmedicine.diseaseHealth SurveysCross-Sectional StudiesSpainChronic DiseaseAnxietyFemalemedicine.symptombusinessBody mass indexDemography
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