Search results for "CISS"
showing 10 items of 127 documents
The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases
2019
© The Author(s) 2019.
A Microscopic Description of SARS-CoV-2 Main Protease Inhibition with Michael Acceptors. Strategies for Improving Inhibitors Design
2020
The irreversible inhibition of the main protease of SARS-CoV-2 by a Michael acceptor known as N3 has been investigated using multiscale methods. The noncovalent enzyme–inhibitor complex was simulated using classical molecular dynamics techniques and the pose of the inhibitor in the active site was compared to that of the natural substrate, a peptide containing the Gln–Ser scissile bond. The formation of the covalent enzyme–inhibitor complex was then simulated using hybrid QM/MM free energy methods. After binding, the reaction mechanism was found to be composed of two steps: (i) the activation of the catalytic dyad (Cys145 and His41) to form an ion pair and (ii) a Michael addition where the …
Sexual narcissism and its association with sexual and well-being outcomes
2020
Abstract Theories on narcissism are traditionally closely related to sexuality. Most research on the association between narcissism and sexual behavior, however, has focused on harmful/maladaptive outcomes. The aim of the present two studies was to examine the possible health-promoting influence of both global and sexual narcissism on sexual function and genital self-image. In Study 1, sexual narcissism was positively associated with sexual functioning in both women and men (N = 505, online-recruited German participants). In the women's sample, sexual narcissism was related to a positive genital self-image. The facet sexual skill was identified as the most important predictor for sexual fun…
Validation of the Short Dark Triad in a German Sample
2021
Abstract. The structure, correlates, and assessment of the Dark Triad are widely discussed in several fields of psychology. Based on the German version of the Short Dark Triad (SDT), we add to this by (a) providing a competitive test of existing structural models, (b) testing the nomological network, and (c) proposing an ultrashort 9-item version of the SDT (uSDT). A sample of N = 969 participants provided data on the SDT and a range of further measures. Our competitive test of five structural models revealed that fit indices and nomological network assumptions were best met in a three-factor model, with separate factors for psychopathy, Machiavellianism, and narcissism. The results provid…
The Relationships Between the Dark Triad, the Moral Judgment Level, and the Students’ Disciplinary Choice
2016
Abstract. The purpose of the present study was to examine the relationships between the personality traits of the Dark Triad, the moral judgment level, and the students’ disciplinary choice. It was hypothesized that students who major in higher business and management education show higher levels of the Dark Triad and lower levels of moral judgment competence (self-selection hypothesis). According to the indoctrination hypothesis it was assumed that the differences between business and management students and other students would be higher in advanced semesters. The findings suggest that business and management students show higher levels of the Dark Triad but not of moral judgment compete…
A Process × Domain Assessment of Narcissism: The Domain-Specific Narcissistic Admiration and Rivalry Questionnaire
2022
Research on grandiose narcissism distinguishes between self-promotional processes (i.e., narcissistic admiration) and other-derogative processes (i.e., narcissistic rivalry; Back et al., 2013). Moreover, research has begun to assess and investigate narcissistic manifestations in different domains (e.g., communal narcissism). To integrate these two lines of research, we developed the Domain-Specific Narcissistic Admiration and Rivalry Questionnaire (D-NARQ), a 72-item narcissism questionnaire that contains a self-promotional process scale (narcissistic admiration) and an other-derogatory process scale (narcissistic rivalry) for four domains: intellectual ability, social dominance, communal …
Narcissistic Traits and Explicit Self-Esteem: The Moderating Role of Implicit Self-View
2016
Objective: Whilst the relationship between narcissism and self-esteem has been studied for a long time, findings are still controversial. The majority of studies investigated narcissistic grandiosity, neglecting the existence of vulnerable manifestations of narcissism. Moreover, recent studies have shown that grandiosity traits are not always associated with inflated explicit self-esteem. The aim of the present study is to investigate the relationship between narcissistic traits and explicit self-esteem, distinguishing between grandiosity and vulnerability. Moreover, we consider the role of implicit self-esteem in qualifying these associations. Method: Narcissistic traits, explicit and impl…
Effect of mycorrhizal inoculation on metal accumulation by poplar leaves at phytomanaged sites
2017
Abstract Phytotechnologies for the management of lands contaminated with potentially toxic elements (PTEs) are considered as gentle alternatives to conventional remediation techniques. During the last few years, phytotechnologies have progressively shifted to phytomanagement, a concept that includes the valorization of the plant biomass produced on the contaminated site. This study aimed at evaluating the mid-term effect of ecto- and endomycorrhizal inoculation on the reduction of PTE mobility in soils and foliar accumulation by two poplar clones, Skado ( Populus trichocarpa x P. maximowiczii ) and I-214 ( P. deltoides x P. nigra ), dedicated to bioenergy purposes. The effects of inoculatio…
The Two Dimensions of Narcissistic Personality and Support for the Radical Right: The Role of Right–Wing Authoritarianism, Social Dominance Orientati…
2020
This paper offers an explanation of the link between grandiose narcissism and support for radical right parties. Drawing on representative data of the GESIS Panel ( N = 2827), focusing on support for the German radical right populist party Alternative for Germany in 2016 and treating grandiose narcissism as a two–dimensional concept, it is shown that the effects of grandiose narcissism are indirect rather than direct. The paper also reveals that it is mainly narcissistic rivalry that accounts for radical right party support, whereas narcissistic admiration has a protecting relationship. Finally, our results indicate that the indirect effects of narcissistic rivalry on radical right party s…
Dall?emergenza sanitaria all?emergenza economica: l?eccessiva onerosità sopravvenuta tra buona fede e obbligo di rinegoziazione.
2020
The paper focuses on the remedy of the rescission of the contract, underlining how the current situation of economic difficulty resulting from the pandemic, from a remedial point of view, finds in the good faith the most appropriate instrument for the protection of the contract.