Search results for "CIT"
showing 10 items of 22474 documents
Interactions of membranes with coarse-grain proteins: a comparison
2012
We study the interactions between lipid bilayers and rigid transmembrane proteins by Monte Carlo simulations of generic coarse-grain models. Different popular protein models are considered and compared with each other, and key parameters such as the hydrophobicity and the hydrophobic mismatch are varied systematically. Furthermore, the properties of the membrane are manipulated by applying different tensions. The response of the membrane to the insertion of single proteins is found to be mostly generic and independent of the choice of the protein model. Likewise, the orientational distributions of single proteins depend mainly on the hydrophobic mismatch and the hydrophobicity of the protei…
I tre paesaggi della Conca d'Oro
2013
La strategia partecipativa dell’ETM ha determinato un quadro conoscitivo delle necessità di spazi e servizi pubblici degli abitanti di una sezione mare-monte del territorio sud-est della città di Palermo. Un’area campione scelta per verificare se ci sono ancora i margini per recuperare le parti residuali del famoso paesaggio della Conca d’oro. E’ stato elaborato un master-plan d’interventi di riqualificazione, inseriti lungo la direttrice di via Laudicina e via Cassaro, dalla costa fino alle colline, che si propone di recuperare edifici ed aree dismesse, valorizzare orti e giardini, canali d’acqua della vecchia struttura per l’irrigazione, migliorare le infrastrutture. Si propongono alla co…
Kuvallistettu kuuluminen : valokuvahaastattelu ja visuaalinen analyysi paikkasuhteiden tutkimuksessa
2016
Spatial belonging is understood as a multidimensional process in which pictorial representation of the environment also plays an important role. However, various intersecting discursive and personal dimensions in the relations between images, photography and spatial belonging make researching the topic quite challenging. This article focuses on a methodology that combines photo-elicitation and visual analysis to elucidate the relations between images and spatial belonging, and to explore the ways in which the mental images created by discursive landscape imagery can affect the formation of people’s place relations and feelings of spatial belonging. The article draws from a research project …
NMDA receptor antagonists and pain relief: A meta-analysis of experimental trials
2019
ObjectiveWe conducted a meta-analysis of controlled trials that used experimental models of acute pain and hyperalgesia to examine the analgesic effects of NMDA receptor (NMDAR) antagonists.MethodsSix major databases were systematically searched (to March 2018) for studies using human evoked pain models to compare NMDAR antagonists with no-intervention controls. Pain outcome data were analyzed with random-effects meta-analysis.ResultsSearches identified 70 eligible trials (n = 1,069). Meta-analysis found that low-dose ketamine (<1 mg/kg) produced a decrease in hyperalgesic area (standardized mean difference 0.54, 95% confidence interval [CI] 0.34, 0.74, p < 0.001) and a 1.2-point decr…
Neurophysiological Changes After Paired Brain and Spinal Cord Stimulation Coupled With Locomotor Training in Human Spinal Cord Injury
2021
Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via repeated stimulation and locomotor training are not commonly employed in research even though combination of interventions is a common clinical practice. In this randomized clinical trial, we established neurophysiological changes when transcranial magnetic stimulation (TMS) of the motor cortex was paired with transcutaneous thoracolumbar spinal (transspinal) stimulation in human spinal cord injury (SCI) delivered during locomotor training. We hypothesized that TMS delivered before transspinal (TMS-transspinal) stimulation promotes functional reorganization of spinal networks during stepping. In this p…
The effects of motor imagery and Paired associative stimulation on cortical excitability
2009
ABSTRACT Kumpulainen, Susanne 2009. The effect of PAS and motor imagery on the excitability of the motor cortex. Department of Biology of Physical Activity, University of Jyväskylä. Master’s theses of biomechanics. 41 pages. The plasticity of the brain is an increasingly important topic for physical therapists interested in (re)learning and repair following injury. A number of potential endogenous and exogenous protocols have been developed with the improved understanding of the mechanisms of synaptic plasticity. The purpose of this study was twofold: First, the effect of motor imagery of plantarflexion on motor cortex excitability was investigated since it has been shown that motor imagery…
Modulation of plasticity of the soleus area of the motor cortex using paired associative stimulation
2015
Paired associative stimulation (PAS) repeatedly combines single somatosensory nerve stimuli with single transcranial magnetic stimuli to induce bidirectional changes in the excitability of the cortical projections to the target muscle. PAS and motor training have been shown to share common neural mechanisms, suggesting that PAS tests functionally relevant neuronal circuits. While PAS has been used extensively to target the hand area of the motor cortex, few studies have targeted the leg area of the motor cortex. The optimal interstimulus inter- val (ISI) to induce plasticity in the cortical projections to lower limbs is still not well established. Thus, the first purpose of this thesis was …
The effect of paired associative stimulation-induced long-term potentiation-like plasticity on visuomotor learning
2014
Aivojen hermostollisissa rakenteissa ja toiminnassa tapahtuu adaptaatiota motorisen oppimisen seurauksena. Eräs ehdotetuista malleista, johon muutokset voivat perustua on hermoliitoksen voimakkuuden pitkäaikainen tehostuminen eli pitkäkestoinen potentiaa-tio (LTP). Keinotekoisesti LTP:n kaltainen vaikutus voidaan tuottaa parillisella as-sosiatiivisella stimulaatiolla (PAS). Lisäksi tutkimustulokset osoittavat, että PAS voi parantaa tietyn tyyppistä motorista oppimista. Tämän tutkimuksen tarkoituksena on sel-vittää miten PAS:n tuottama LTP:n kaltainen plastisuus vaikuttaa visuomotorisen oppi-misen alkuvaiheeseen. Visuomotorinen oppimistehtävä suoritettiin kolme kertaa PAS:n jälkeen. Oppimist…
Editoriale Uruk la città
2010
Il testo mette le basi della nuova collana Uruk che intende pubblicare numeri monografici sui temi della città contemporanea il riferimento a uruk-la prima città sollecita un nuovo interesse per un progetto sociale per una città nuova, un continuum urbano in cui è il paesaggio l'unica infrastruttura possibile
Elektroutlenianie przepracowanego oleju 15W-40
2017
W pracy przedstawiono badania nad możliwością wykorzystania odpadowego oleju silnikowego 15W-40 do bezpośredniego pozyskiwania energii elektrycznej. Pomiary obejmowały elektroutlenianie emulsji odpadowego (zużytego) oleju silnikowego 15W-40 na gładkiej elektrodzie platynowej w kwasowym elektrolicie (H2SO4). Do wytworzenia emulsji wykorzystano detergent Syntanol DS-10. Pomiary przeprowadzono w temperaturze 293-333K. Maksymalna uzyskana gęstość prądu wyniosła 19 mA/cm2 (dla temp. 333K). Badania wykazały możliwość bezpośredniego wytwarzania prądu elektrycznego z odpadowego oleju silnikowego 15W40, a więc możliwość zasilania nim ogniw paliwowych.