Search results for "CIT"

Maria Carmela Roccheri

2012

Research focus Control of autophagy during both physiological development and in stress conditions in the sea urchin embryo. Model system Sea urchin embryo and larvae in development. Education and career 1971, biology degree, University of Palermo, Italy; advisor: G. Giudice. 1972–1973, fellowship from the Italian Ministry of Public Education, Institute of Comparative Anatomy, University of Palermo. 1974–1980, associate scientist at the Institute of Comparative Anatomy, University of Palermo. 1981–2005, associate professor of cell biology, Department of Cell and Development Biology, University of Palermo. 2000–2005, member of the scientific committee for PhD in “Biotechnology applied to pre…

Vanadium Toxicity Monitored by Fertilization Outcomes and Metal Related Proteolytic Activities in Paracentrotus lividus Embryos

2022

Metal pharmaceutical residues often represent emerging toxic pollutants of the aquatic environment, as wastewater treatment plants do not sufficiently remove these compounds. Recently, vanadium (V) derivatives have been considered as potential therapeutic factors in several diseases, however, only limited information is available about their impact on aquatic environments. This study used sea urchin embryos (Paracentrotus lividus) to test V toxicity, as it is known they are sensitive to V doses from environmentally relevant to very cytotoxic levels (50 nM; 100 nM; 500 nM; 1 µM; 50 µM; 100 µM; 500 µM; and 1 mM). We used two approaches: The fertilization test (FT) and …

Exposure to cytotoxic concentrations of manganese and effects on development

2009

Manganese is one of the most abundant metals present in nature in trace amounts, which is accumulated and utilized by all forms of life. It plays a multitude of biological roles, but exposure of cells/organisms to high levels causes toxicity. In the marine environment, increasing concentrations of bio-available ions often result from anthropogenic activities, and, consequently, manganese represents a new emergent factor in environmental contamination. To study cyto-toxicity of manganese on development, we used an excellent model system as sea urchin embryos Paracentrotus lividus. In this work, we show results from two-dimensional gel electrophoresis (2DE) analysis that highlighted qualitati…

Sea urchin embryos cadmium exposed as an experimental model system for studying the relationship between autophagy and apoptosis

2012

Strategies in experimental models for evaluating apoptosis.

2008

Towards a framework for assessment and management of cumulative human impacts on marine food webs

2015

Effective ecosystem-based management requires understanding ecosystem responses to multiple human threats, rather than focusing on single threats. To understand ecosystem responses to anthropogenic threats holistically, it is necessary to know how threats affect different components within ecosystems and ultimately alter ecosystem functioning. We used a case study of a Mediterranean seagrass (Posidonia oceanica) food web and expert knowledge elicitation in an application of the initial steps of a framework for assessment of cumulative human impacts on food webs. We produced a conceptual seagrass food web model, determined the main trophic relationships, identified the main threats to the fo…

The Role of Excited Oxygen Molecules in the Formation of the Secondary Ozone Layer at 87 to 97 km

2018

The secondary ozone layer is located at elevations of 87 to 97 km in the upper mesosphere – lower thermosphere. It overlaps with the ionospheric D-layer. Daytime intensive UV radiation is dissociating O2 molecules to O atoms and photoexcitating O2 molecules up to 11.07eV level. Ozone photolysis between the wavelengths of 118.7–121.6 nm produces three oxygen atoms from one ozone molecule. Collision reactions of O2(B3 Σu —) and O2(X3 Σg —, υ≥26) with O2(X3 Σg —, υ=0) produce additional oxygen atoms. The number of oxygen atoms is maintained at such a high level that a small but significant ozone concentration survives. UV radiation weakens radically during the night. The number of O atoms show…

Caracterización molecular de las neoplasias mieloides relacionadas con la terapia

2018

Las neoplasias mieloides relacionadas con la terapia (NMRT) se definen como aquellas leucemias mieloblásticas agudas (LMA) ó síndromes mielodisplásicos (SMD) desarrollados en pacientes previamente tratados con quimioterapia, radioterapia ó la combinación de ambas por una patología previa. Constituyen una de las mayores complicaciones de los supervivientes de otras formas de cáncer, representando entre un 10-20% de las LMA en el momento actual. Además, se presupone una incidencia en aumento a medio plazo debido a la mejora en la supervivencia de los pacientes oncológicos. Por otro lado se considera un grupo de pacientes con mal pronóstico per se aunque se les aplican los mismos factores de r…

The triad approach for assessment of industrial contamination in freshwater sediments, Opole Region, Poland,

2007

Toxicity of silver nanoparticles to Lumbriculus variegatus is a function of dissolved silver and promoted by low sediment pH

2018

Toxicity of silver nanoparticles (AgNPs) to benthic organisms is a major concern. The use of AgNPs in industry and consumer products leads to increasing release of AgNPs into the aquatic environment—sediments being the major sink. Effects of sediment pH on the toxicity of AgNPs to benthic oligochaeta Lumbriculus variegatus were studied in a 23‐d toxicity test. Artificially prepared sediments (pH 5 and 7) were spiked with varying concentrations of uncoated AgNP, polyvinylpyrrolidone (PVP)‐coated AgNP, and silver nitrate (AgNO3) as dissolved Ag reference. Number of individuals and biomass change were used as endpoints for the toxicity. The toxic effects were related to the bioaccessible conce…