Search results for "CIT"

showing 10 items of 22474 documents

Neuronal effects of Sugammadex in combination with Rocuronium or Vecuronium.

2017

Rocuronium (ROC) and Vecuronium (VEC) are the most currently used steroidal non-depolarizing neuromuscular blocking (MNB) agents. Sugammadex (SUG) rapidly reverses steroidal NMB agents after anaesthesia. The present study was conducted in order to evaluate neuronal effects of SUG alone and in combination with both ROC and VEC. Using MTT, CASP-3 activity and Western-blot we determined the toxicity of SUG, ROC or VEC in neurons in primary culture. SUG induces apoptosis/necrosis in neurons in primary culture and increases cytochrome C (CytC), apoptosis-inducing factor (AIF), Smac/Diablo and Caspase 3 (CASP-3) protein expression. Our results also demonstrated that both ROC and VEC prevent these…

vecuroniumNecrosisEstrès oxidatiuPrimary Cell CulturerocuroniumCaspase 3NeuronesPharmacologySugammadexSugammadex03 medical and health sciences0302 clinical medicine030202 anesthesiologymedicineAnimalsHumansAndrostanolsRocuroniumCell damageNeuronsVecuronium BromideDose-Response Relationship DrugCaspase 3business.industryapoptosis.Apoptosis Inducing FactorCytochromes c030208 emergency & critical care medicineGeneral Medicinemedicine.diseaseneuronRatsDrug Combinationsmedicine.anatomical_structureGene Expression RegulationApoptosisToxicityNeuronNeuromuscular Blocking Agentsmedicine.symptombusinessResearch Papergamma-Cyclodextrinsmedicine.drug
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Flow cytometric analysis of chronic and acute toxicity of copper(II) on the marine dinoflagellateAmphidinium carterae

2001

Background Copper(II) is a heavy metal whose levels have increased in some marine ecosystems to polluting levels. Dinoflagellates, an important phytoplankton group, are at the base of aquatic food chains and bioaccumulation of copper by these microorganisms can result in complex ecosystem alterations, so we investigated how copper disturbs those cells. Methods Cytotoxic effects of sublethal and lethal copper concentrations ranging from 4.2 nM (control condition) to 3.13 μM estimated labile copper were studied in batch cultures of Amphidinium carterae. Cell morphology, motility, autofluorescence, and fluorescein diacetate (FDA)–dependent fluorescence generation were evaluated by flow cytomet…

ved/biologyIntracellular pHCopper toxicityved/biology.organism_classification_rank.speciesBiophysicschemistry.chemical_elementCell BiologyHematologyBiologymedicine.diseaseCell morphologyCopperAcute toxicityPathology and Forensic Medicinechemistry.chemical_compoundEndocrinologychemistryBiochemistryAmphidinium carteraemedicineFluoresceinChlorophyll fluorescenceCytometry
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Antibacterial activity and cytotoxicity of selected Egyptian medicinal plants.

2011

Medicinal plants have been used as a source of remedies since ancient times in Egypt. The present study was designed to investigate the antibacterial activity and the cytotoxicity of the organic extracts from 16 selected medicinal plants of Egypt. The study was also extended to the isolation of the antiproliferative compound jaeschkeanadiol p-hydroxybenzoate (FH-25) from Ferula hermonis. The microbroth dilution was used to determine the minimal inhibitory concentration (MIC) of the samples against twelve bacterial strains belonging to four species, Providencia stuartii, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli, while a resazurin assay was used to assess the cytoto…

ved/biology.organism_classification_rank.speciesPharmaceutical ScienceBreast NeoplasmsMicrobial Sensitivity TestsProvidenciamedicine.disease_causeAnalytical Chemistrychemistry.chemical_compoundMinimum inhibitory concentrationInhibitory Concentration 50MagnoliopsidaCell Line TumorKlebsiellaPseudomonasDrug DiscoverymedicineEscherichia coliHumansVitisCytotoxicityMedicinal plantsEscherichia coliPharmacologyLeukemiaPlants MedicinalbiologyTraditional medicineved/biologyPlant ExtractsProvidencia stuartiiOrganic ChemistryResazurinbiology.organism_classificationAntineoplastic Agents PhytogenicAnti-Bacterial AgentsFerulaComplementary and alternative medicinechemistryDrug Resistance NeoplasmMolecular MedicineEgyptFemaleAntibacterial activitySesquiterpenesFerula hermonisPhytotherapyPlanta medica
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In-Depth Characterization of Bioactive Extracts from Posidonia oceanica Waste Biomass

2019

© 2019 by the authors.

ved/biology.organism_classification_rank.speciesPhytochemicalsPharmaceutical ScienceBiomassMicrobiologiaantioxidant capacity7. Clean energy01 natural sciencesEcologia marinaAntioxidantsFoodborne Diseaseschemistry.chemical_compoundMicevalorisationAnti-Infective AgentsDrug DiscoveryFood scienceAntifungal activityBiomasslcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Caliciviridae InfectionsPlant Proteinschemistry.chemical_classificationFeline calicivirusAlismatalesbiologyultrasound04 agricultural and veterinary sciences040401 food scienceantiviralLipids6. Clean waterAntioxidant capacityMicrobiologia marinaPosidonia oceanicaMitosporic FungiValorisationValorisationMicrobial Sensitivity TestsPolysaccharideArticle0404 agricultural biotechnologyPhenolsPolysaccharidesUltrasoundAnimalsHumansAntiviralHot water extractionEthanolEthanol010405 organic chemistryved/biologyPlant Extractsantifungal activityNorovirusWaterbiology.organism_classification0104 chemical sciencesEcologiaHot water extractionRAW 264.7 Cellslcsh:Biology (General)chemistryCatsSolventsAntiviralesQuímica Analíticahot water extractionMurine norovirusCalicivirus FelineMarine Drugs
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Alcune osservazioni su Riolo e i suoi disegni

2015

Tommaso Riolo, nacque a Palermo nel 1815 da una famiglia di artisti. Nipote del più famoso pittore Vincenzo (Palermo 1772-1837), il suo apprendistato si svolse proprio presso lo zio paterno, nella città natale. I suoi lavori furono esposti fin dagli esordi della sua carriera nei cataloghi delle Esposizioni di Belle Arti tenutesi a Palermo dal 1841 al 1875 . Sebbene le vedute del pittore riguardino prevelentemente luoghi e architetture palermitane, alcune rappresentano altre località siciliane. Del consistente corpus di più di settanta fra disegni, acquerelli e litografie, custoditi presso il Gabinetto di Disegni e Stampe della Galleria regionale della Sicilia di palazzo Abatellis, nove, dat…

vedute di città architetture siciliane dell'Ottocento Tommaso RioloSettore ICAR/18 - Storia Dell'Architettura
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Role of vegetation on flow hydrodynamics and erosion processes

2011

vegetation flow velocity erosion
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ANALYSIS OF VELOCITY FIELD AND TURBULENCE CHARACTERISTICS OF FLOW IN A VEGETATED LABORATORY FLUME

2011

Vegetation altering hydrodynamic conditions of an open channel flow controls the exchanges of sediment, nutrients and contaminants. Thus, the knowledge of the hydraulic characteristics of flow over vegetation is very important to support the management of fluvial processes. But, the analysis of the hydrodynamic conditions is complex because vegetation is flexible in varying degrees and it oscillates in the flow changing position. Furthermore, because of temporal changing of roughness due to natural vegetative growth, the response of vegetation to the flow can change in time. Many theoretical and experimental investigations have been performed in order to analyze both the mean flow and turbu…

vegetation flow velocity experiment
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Experimental analysis of flow in a laboratory flume with flexible vegetation

2011

vegetation velocity simulation
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Log velocity profile and bottom displacement for a flow over a very flexible submerged canopy

2007

Management of shallow lagoons and salt marsh environments usually requires use of numerical models in order to understand the hydrodynamic characteristics of these basins. In order for these models to give reliable results one has to have good knowledge of the interaction between the flow and the aquatic vegetation, which strongly alters the hydrodynamic characteristics. Many experimental and theoretical studies are available in the technical literature, but, because of the very different vegetation and flow characteristics, they do not yet allow one to have a clear and general knowledge of the phenomena, in terms of both flow resistance and velocity distribution. The latter is very importa…

velocity profileflow resistanceAquatic vegetationflow field
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Numerical Simulations of the Flow Field of a Submerged Hydraulic Jump over Triangular Macroroughnesses

2021

The submerged hydraulic jump is a sudden change from the supercritical to subcritical flow, specified by strong turbulence, air entrainment and energy loss. Despite recent studies, hydraulic jump characteristics in smooth and rough beds, the turbulence, the mean velocity and the flow patterns in the cavity region of a submerged hydraulic jump in the rough beds, especially in the case of triangular macroroughnesses, are not completely understood. The objective of this paper was to numerically investigate via the FLOW-3D model the effects of triangular macroroughnesses on the characteristics of submerged jump, including the longitudinal profile of streamlines, flow patterns in the cavity regi…

velocitylcsh:Hydraulic engineering010504 meteorology & atmospheric sciencesGeography Planning and Development0207 environmental engineering02 engineering and technologyAquatic Science01 natural sciencesBiochemistrySettore ICAR/01 - IdraulicaPhysics::Fluid Dynamicssymbols.namesakelcsh:Water supply for domestic and industrial purposeslcsh:TC1-978triangular macroroughnesseShear stressFroude numberStreamlines streaklines and pathlines020701 environmental engineeringHydraulic jump0105 earth and related environmental sciencesWater Science and Technologylcsh:TD201-500TKEbed shear stress coefficientFLOW-3D modelsubmerged hydraulic jumpTurbulenceMechanicsSupercritical flowTurbulence kinetic energyJumpsymbolsGeologytriangular macroroughnessesWater
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