Search results for "CLASSIFICATION-SYSTEM"
showing 2 items of 2 documents
Describing urban soils through a faceted system ensures more informed decision-making
2016
Urban areas are increasing worldwide at a dramatic rate and their soils definitely deserve more attention than they have received in the past. In urban environments, soils potentially provide the same ecosystem services as in rural and wild environments, although in some cases they are depleted of their basic functions, such as when they lose their productive and filtering capacities because of sealing, and become mere supports for infrastructures. In other cases, soils of urban areas acquire new functions that are unique to these environments. Current soil classifications fail to effectively account for the complexity of urban soils and the information that is required for their management…
Formulation predictive dissolution (fPD) testing to advance oral drug product development: an introduction to the US FDA funded ‘21st Century BA/BE’ …
2018
Over the past decade, formulation predictive dissolution (fPD) testing has gained increasing attention. Another mindset is pushed forward where scientists in our field are more confident to explore the in vivo behavior of an oral drug product by performing predictive in vitro dissolution studies. Similarly, there is an increasing interest in the application of modern computational fluid dynamics (CFD) frameworks and high-performance computing platforms to study the local processes underlying absorption within the gastrointestinal (GI) tract. In that way, CFD and computing platforms both can inform future PBPK-based in silico frameworks and determine the GI-motility-driven hydrodynamic impac…