Search results for "CLO"

showing 10 items of 9986 documents

Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD

2021

Background and aim: Coffee intake exerts protective effects against non-alcoholic fatty liver disease (NAFLD), although without fully cleared mechanisms. In this study we aimed to assess whether coffee consumption may influence the expression of long non-coding RNAs (lncRNAs) in the liver. Methods: C57BL/6J mice were fed a 12-week standard diet (SD), high-fat diet (HFD) or HFD plus decaffeinated coffee solution (HFD + coffee). Expression of specific lncRNAs involved in NAFLD was analyzed by real-time PCR. For the most differentially expressed lncRNAs, the analysis was also extended to their mRNA targets. Results: Decaffeinated coffee intake reduced body weight gain, prevented NAFLD, lowered…

lncRNA.Liver CirrhosisMalemedicine.medical_specialtyGm16551; H19; NAFLD; coffee; lncRNA; Animals; Coffee; Disease Models Animal; Fatty Liver; Gene Expression; Liver; Liver Cirrhosis; Male; Mice; Mice Inbred C57BL; Non-alcoholic Fatty Liver Disease; RNA Long NoncodingCoenzyme ACircadian clockcoffeeGene ExpressionBiologyInbred C57BLArticlechemistry.chemical_compoundMicelncRNADownregulation and upregulationFibrosisSettore BIO/13 - Biologia ApplicataNon-alcoholic Fatty Liver DiseaseInternal medicineNAFLDmedicineAnimalsTX341-641Messenger RNANutrition and DieteticsH19Nutrition. Foods and food supplyAnimalGm16551Fatty liverNAFLD; coffee; lncRNA; Gm16551; H19nutritional and metabolic diseasesmedicine.diseaseMice Inbred C57BLFatty LiverDisease Models AnimalEndocrinologychemistryLiverLipogenesisDisease ModelsRNARNA Long NoncodingLong NoncodingSteatosisFood Science
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Dicyclopentaannelated Hexa-peri-hexabenzocoronenes with a Singlet Biradical Ground State

2021

Abstract Synthesis of two dicyclopentaannelated hexa‐peri‐hexabenzocoronene (PHBC) regioisomers was carried out, using nonplanar oligoaryl precursors with fluorenyl groups: mPHBC 8 with two pentagons in the “meta”‐configuration was obtained as a stable molecule, while its structural isomer with the “para”‐configuration, pPHBC 16, could be generated and characterized only in situ due to its high chemical reactivity. Both PHBCs exhibit low energy gaps, as reflected by UV‐vis‐NIR absorption and electrochemical measurements. They also show open‐shell singlet ground states according to electron paramagnetic resonance (EPR) measurements and density functional theory (DFT) calculations. The use of…

low energy gapnot-fully benzenoid PAH010402 general chemistryPhotochemistry01 natural sciencesCatalysislaw.inventiondicyclopentaannelationopen-shell biradicallawStructural isomerMoleculeSinglet stateElectron paramagnetic resonance010405 organic chemistryChemistryCommunicationAromaticityGeneral ChemistryCommunications0104 chemical sciencesDensity functional theoryPolycyclic Aromatic Hydrocarbons | Hot Paperhexa-peri-hexabenzocoroneneGround stateAntiaromaticityAngewandte Chemie International Edition
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Suomalainen aikakauslehti, lukijan tarpeet ja mediamurros

2016

This thesis discusses commercial Finnish magazines in the midst of media disruption. First, this research clarifies what has been the core content of printed magazines. Then this study focuses on finding out what kind of reader needs the producers of these magazines tried to satisfy. The purpose of this study is to discuss, whether the core content of magazines and the methods of satisfying the readers’ needs could be transferred to the digital media environment and in what way. The theoretical framework of this study is the notion of media concept. It allows viewing magazines as a vast whole and demonstrates a relationship between content and the audience’s needs. In addition, this study u…

lukijatdigitisationtarpeetmediaComputingMilieux_GENERALreadermedia conceptodotuksetcontentuusmediaGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)magazineaikakauslehdetneeds
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Molecular cloning and characterization of the complementary DNA coding for the B-chain of murine Clq

1989

AbstractcDNA clones coding for the B-chain of murine Clq were isolated from a mouse macrophage library. The characterized clones include the total coding region plus a leader sequence. High homology was found with human Clq B-chain in the coding region (81%). Northern blot analysis of total RNA from different tissues of Balb/c mice showed one band of approximately 1.2 kb. The highest signal was found in RNA preparations of thioglycolate-activated peritoneal macrophages. The probe also hybridized with mRNA from spleen, thymus and heart. Extremely weak signals were found in liver, kidney, lung and intestine tissues.

mRNAMolecular Sequence DataBiophysicsProtein Sorting SignalsMolecular cloningBiologyBiochemistryMiceStructural BiologySequence Homology Nucleic AcidComplementary DNAGeneticsAnimalsHumansCoding regionGenomic libraryRNA MessengerNorthern blotCloning MolecularPromoter Regions GeneticMolecular BiologyGeneMice Inbred BALB CMessenger RNAComplement C1qNucleic Acid HybridizationRNADNARNA ProbesCell BiologyBlotting NorthernMolecular biologyClqNucleotide sequenceCloningFEBS Letters
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Transfer Learning of Deep Learning Models for Cloud Masking in Optical Satellite Images

2023

Los satélites de observación de la Tierra proporcionan una oportunidad sin precedentes para monitorizar nuestro planeta a alta resolución tanto espacial como temporal. Sin embargo, para procesar toda esta cantidad creciente de datos, necesitamos desarrollar modelos rápidos y precisos adaptados a las características específicas de los datos de cada sensor. Para los sensores ópticos, detectar las nubes en la imagen es un primer paso inevitable en la mayoría de aplicaciones tanto terrestres como oceánicas. Aunque detectar nubes brillantes y opacas es relativamente fácil, identificar automáticamente nubes delgadas semitransparentes o diferenciar nubes de nieve o superficies brillantes es mucho …

machine learningflood detectioncloud maskingtransfer learningUNESCO::CIENCIAS TECNOLÓGICAS
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Rare‐earth cyclobutadienyl sandwich complexes: Synthesis, structure and dynamic magnetic properties

2018

The potassium cyclobutadienyl [K2{η4‐C4(SiMe3)4}] (1) reacts with MCl3(THF)3.5 (M=Y, Dy) to give the first rare‐earth cyclobutadienyl complexes, that is, the complex anions [M{η4‐C4(SiMe3)4}{η4‐C4(SiMe3)3‐κ‐(CH2SiMe2}]2−, (2M), as their dipotassium salts. The tuck‐in alkyl ligand in 2M is thought to form through deprotonation of the “squarocene” complexes [M{η4‐C4(SiMe3)4}2]− by 1. Complex 2Dy is a single‐molecule magnet, but with prominent quantum tunneling. An anisotropy barrier of 323(22) cm−1 was determined for 2Dy in an applied field of 1 kOe, and magnetic hysteresis loops were observed up to 7 K. nonPeerReviewed

magneettiset ominaisuudetcyclobutadienyl ligandsmagneetitchemistry.chemical_element010402 general chemistry01 natural sciencesCatalysisDeprotonationAnisotropyta116magnetsAlkylQuantum tunnellingchemistry.chemical_classificationkemiallinen synteesiorganometallics dysprosium010405 organic chemistryLigandOrganic ChemistrykompleksiyhdisteetGeneral Chemistryharvinaiset maametallitMagnetic hysteresis0104 chemical sciencesCrystallographychemistryMagnetDysprosiumsingle-moleculerare-earth elements
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Experimental evidence on microwave induced electron losses from ECRIS plasma

2018

The balance between warm and hot (>1 keV) electron density and their losses from the magnetic confinement system of an Electron Cyclotron Resonance Ion Source (ECRIS) plasma is considered to be one of the main factors determining the rate of the high charge state ion production. One of the key loss channels for heated electrons is thought to be induced by the injected microwaves. While this loss mechanism, referred to as rf-induced pitch angle scattering, has been studied theoretically and with computational tools, direct experimental evidence of its significance in minimum-B ECRIS plasmas remains limited. In this work, experimental evidence of microwave induced electron losses in the axial…

magnetic mirrorsElectron densityelectrorheological fluidsAtmospheric-pressure plasma7. Clean energy01 natural scienceselectromagnetic radiationElectron cyclotron resonance010305 fluids & plasmassähkömagneettinen säteilyMagnetic mirrormikroaallotion sources0103 physical sciencesplasma (kaasut)010302 applied physicsPhysicsplasma confinementta114Magnetic confinement fusionPlasmaCondensed Matter Physicselectronic structureIon sourcePlasma diagnosticsAtomic physicsPhysics of Plasmas
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Influence of axial mirror ratios on the kinetic instability threshold in electron cyclotron resonance ion source plasma

2022

International audience; Electron Cyclotron Resonance (ECR) ion source plasmas are prone to kinetic instabilities. The onset of the instabilities manifests as emission of microwaves, bursts of electrons expelled from the plasma volume, and the collapse of the extracted highly charged ion (HCI) currents. Consequently, the instabilities limit the HCI performance of ECR ion sources by limiting the parameter space available for ion source optimization. Previous studies have shown that the transition from stable to unstable plasma regime is strongly influenced by the magnetic field structure, especially the minimum field value inside the magnetic trap (Bmin). This work focuses to study the role o…

magnetic mirrorsplasma confinementsyklotronit[PHYS.PHYS.PHYS-ACC-PH]Physics [physics]/Physics [physics]/Accelerator Physics [physics.acc-ph]plasma heatingplasma instabilitieshiukkaskiihdyttimetelectron energy distribution functionsplasmafysiikkaCondensed Matter Physicsion sourcesPhysics::Plasma Physicscyclotron resonanceions and propertiesplasma (kaasut)
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Motivic Pattern Extraction in Music, and Application to the Study of Tunisian Modal Music

2007

A new methodology for automated extraction of repeated patterns in time-series data is presented, aimed in particular at the analysis of musical sequences. The basic principles consists in a search for closed patterns in a multi-dimensional parametric space. It is shown that this basic mechanism needs to be articulated with a periodic pattern discovery system, implying therefore a strict chronological scanning of the time-series data. Thanks to this modelling global pattern filtering may be avoided and rich and highly pertinent results can be obtained. The modelling has been integrated in a collaborative pro ject between ethnomusicology, cognitive sciences and computer science, aimed at the…

mallintaminenpattern extractionEngineeringaikasarjatmusiikkiséquences temporelles[MATH] Mathematics [math]02 engineering and technology[INFO] Computer Science [cs]Space (commercial competition)computer.software_genre060404 musicanalyse musicalemusiikkianalyysi020204 information systemsmotifs périodiques0202 electrical engineering electronic engineering information engineering[INFO]Computer Science [cs]improvisointiTime series[MATH]Mathematics [math]modaalisuus (musiikki)Parametric statisticsmusic analysismotifs fermésbusiness.industrymusique modale tunisienneextraction de motifstunisian modal musicjaksolliset ilmiöt06 humanities and the artsGeneral MedicineClosed patterntime-series dataarabialainen musiikkiclosed patternMusic theoryEthnomusicologyArtificial intelligencebusinesscomputer0604 artsNatural language processingperiodic pattern
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Security in Modern Smart Cities: An Information Technology Perspective

2019

In a big and modern city, the security system is not a single-layered single module system. Instead, it consists of many layers with autonomous subsystems which are capable of interfacing reciprocally in an efficient and coordinated way horizontally and vertically. The design of such indigenous subsystems and ensuring tight interaction between them while taking into account high usability and resource utilization is not a simple task. In this regard, this article provides a comprehensive overview of the security systems in smart cities. We begin by introducing trends and key stakeholders in smart cities. Next, we provide examples of mass surveillance systems in developed countries like the …

mass surveillancesmart citiesSIMPLE (military communications protocol)turvallisuusComputer sciencebusiness.industryInformation technologyUsabilityCloud computingsecuritysuurkaupungitIndigenousTask (project management)Engineering managementautonomous systemsInterfacingKey (cryptography)älytekniikkatarkkailubusiness2019 2nd International Conference on Communication, Computing and Digital systems (C-CODE)
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