Search results for "CM1"
showing 2 items of 2 documents
A novel mutation of the extracellular matrix protein 1 gene (ECM1) in a patient with lipoid proteinosis (Urbach-Wiethe disease) from Sicily
2005
Summary Background Lipoid proteinosis (LP), also known as Urbach–Wiethe disease, is a rare autosomal recessive disorder characterized by a hoarse voice, warty skin infiltration and scarring. Mutations within the extracellular matrix protein 1 (ECM1) gene cause LP. Objectives We report the molecular analysis of the ECM1 gene in a Sicilian patient with LP in order to extend the mutation spectrum of this genodermatosis. Methods We studied a 32-year-old female born from consanguineous parents who was diagnosed at the age of 11 years as having LP. She has a clinical phenotype corresponding to Urbach–Wiethe disease characterized by papules/nodules, indurated plaques and sometimes ulcerated les…
Pour une politique de la qualité de l'école primaire en Afrique : évaluation des acquis des élèves en CP et en CM au Togo
1993
Policy decisions in education cannot be made upon opinions and subjectives factors ; this is especially true in African countries where demographic and economic constraints are particularly binding. A key element is to measure the impact of the various factors affecting student learning, even though this step has to be complemented by cost estimates so as to produce cost-efficiency indicators. This papers concerns primary schooling in Togo and aims at documenting the link between school factors on the one hand, pupil achievement on the other. The results have very clear consequences in terms of educational policy since they show that inputs such as school building in concrete or recruitemen…