Search results for "COCO"
showing 10 items of 402 documents
Thermal properties of the tetrahydrate series MtM(M'EDTA)2·4H2O {Mt, M, M' = Co(II), Ni(II), Zn(II)}
1992
Abstract We report on the specific heat data of the ordered bimetallic compounds CoCo(CoEDTA) 2 ·4H 2 O and CoCo(NiEDTA) 2 ·4H 2 O in the temperature range 1.5−15 K. The magnetic specific heat is analyzed from an Ising model that assumes three different magnetic sublattices exchange-coupled by two distinct magnetic interactions, as well as local anisotropies on tetrahedral Co and octahedral Ni sites.
PHEA-graft-polybutylmethacrylate copolymer microparticles for delivery of hydrophobic drugs.
2012
Abstract Polymeric microparticles encapsulating two model hydrophobic drugs, beclomethasone dipropionate (BDP) and flutamide (FLU) were prepared by using the high pressure homogenization-solvent evaporation method starting from a oil-in-water emulsion. For the preparation of polymeric microparticles a α,β-poly(N-2-hydroxyethyl)- d , l -aspartamide (PHEA) graft copolymer with comb like structure was properly synthesized via grafting from atom transfer radical polymerization (ATRP) technique, by using two subsequent synthetic steps. In the first step a polymeric multifunctional macroinitiator was obtained by the conjugation of a proper number of 2-bromoisobutyryl bromide (BIB) residues to the…
Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α upregulation in primary human hepatocytes
2013
Abstract Background Organic cation transporter 1 (OCT1, SLC22A1) is a membrane transporter that is important for therapeutic effect of the antidiabetic drug metformin. Its liver-specific expression in hepatocytes is strongly controlled by hepatocyte nuclear factor-4α (HNF4α). HNF4α expression and transcriptional activity have been demonstrated to be augmented by glucocorticoid receptor (GR) in human hepatocytes and rodent livers. Methods It was examined whether GR activation indirectly induces OCT1 gene expression via HNF4α up-regulation in primary human hepatocytes.We also examined which other transcription factors are involved in OCT1 gene expression and whether they are regulated by dexa…
Effects of substrate solarization on tomato soilless cultivation
2008
Aceite de coco: tratamiento alternativo no farmacológico frente a la enfermedad de Alzheimer
2015
Introducción: la enfermedad de Alzheimer es la demencia más prevalente en la actualidad. En cuanto al tratamiento, no existe cura farmacológica definitiva, con lo cual son necesarias nuevas alternativas terapéuticas. En este sentido, los triglicéridos de cadena media suponen una fuente directa de energía celular y pueden ser una alternativa no farmacológica a la muerte neuronal por falta de la misma, que se produce en los enfermos de Alzheimer. Objetivo: evaluar el impacto que tiene el aceite de coco en la evolución de la demencia tipo Alzheimer, en cualquier grado de demencia. Asimismo, determinar si existe influencia en dicha mejora, de variables como el sexo y padecer o no diabetes melli…
Inactivación selectiva del receptor de glucocorticoides en la epidermis de ratón. Defectos en el desarrollo y cáncer de piel
2014
[-] Los glucocorticoides y su receptor Los glucocorticoides (GCs) son hormonas esteroideas que se sintetizan y secretan en las glándulas adrenales como respuesta a señales de estrés externas y cuya síntesis está regulada por el eje hipotálamo-pituitaria-adrenal (HPA) (Taves et al., 2011). Los GCs, cortisol en humanos y corticosterona en ratones, regulan numerosos procesos fisiológicos como el metabolismo de glucosa y lípidos, la respuesta inflamatoria e inmune, el desarrollo fetal y la proliferación y supervivencia celular. Además, son importantes para la maduración de órganos como el pulmón, el riñón y la epidermis entre otros (Pérez, 2011). Además de las funciones básicas fisiológicas ant…
Flavour release as a function of time in sugar matrices, in relation to the perception of their sweetness and taste
2002
Although instrumental or sensory analysis of food flavour profiles is often separated from gustatory studies, certain flavours may be classified as sweet, suggesting an interaction between flavour and aroma in sensory perception mechanisms. This paper contains information on the results of studies aimed at establishing dynamics of flavour and sweetness release in the course of their sensory perception during the mastication of sugar confectionery.
Production d'arôme de noix de coco (pentyl-6-alpha pyrone) par le champignon filamenteux trichoderma
1996
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