Search results for "COD"

5-methylcytosine modification of an Epstein–Barr virus noncoding RNA decreases its stability

2020

Many cellular noncoding RNAs contain chemically modified nucleotides that are essential for their function. The Epstein–Barr virus expresses two highly abundant noncoding RNAs called EBV-encoded RNA 1 (EBER1) and EBER2. To examine whether these viral RNAs contain modified nucleotides, we purified native EBERs from EBV-infected cells and performed mass spectrometry analysis. While EBER2 contains no modified nucleotides at stoichiometric amounts, EBER1 was found to carry 5-methylcytosine (m5C) modification. Bisulfite sequencing indicated that a single cytosine of EBER1 is methylated in ∼95% of molecules, and the RNA methyltransferase NSUN2 was identified as the EBER1-specific writer. Intrigui…

Acanthocephalans from Marine Fishes from Patagonia, Argentina

2019

In this study, 542 individual fish from 20 species from the Patagonian continental shelf of Argentina were examined for acanthocephalans. A total of 1,547 acanthocephalans belonging to 5 species were collected from 18 species of fish. Adult forms were represented by 2 species: Aspersentis johni (Baylis, 1929) (Heteracanthocephalidae) from longtail southern cod, Patagonotothen ramsayi (Regan) (new host record), and Breizacanthus aznari Herna´ndez-Orts, Alama-Bermejo, Crespo, Garcı´a, Raga and Montero, 2012 (Arhythmacanthidae) from raneya, Raneya brasiliensis (Kaup). Immature worms of B. aznari were also collected from the intestine of pink cusk-eel, Genypterus blacodes (Forster) (new host re…

Xanastur (brachiopoda, stringocephalacea) nomen novum pro Xana García-Alcalde, 1972 (non Xana kurdjumov, 1917, hymenoptera, hexapoda)

2021

Garcia-Alcalde (1972) proposed the new genus Xana (type species Xana bubo Garcia-Alcalde, 1972) for a terebratulid brachiopod included in the superfamily Stringocephalacea from the Lower Devonian of the Cantabrian Mountains (Northwestern Spain). In an email message sent on April 3, 2018, the entomologist Dr. Eduardo I. Faundez, from the Patagonia Institute, Magallanes University, Chile, warned the author that Xana was a name previously used by Kurdjumov (1917) for a hymenopteran genus. Xana Garcia-Alcalde, 1972 would be so a later homonym of Xana Kurdjumov, 1917. In accordance with articles 52.3, 52.4, 53.2, 60.3 of the International Code of Zoological Nomenclature (ICZN) (2000), it is prop…

Lucretius Franco-Hibernicus: Dicuil’s Liber de Astronomia and the Carolingian Reception of De Rerum Natura

2020

Abstract Since its coinage in the nineteenth century, the concept of Carolingian renaissance has been primarily based on the revival of classical texts promoted by Charlemagne and his successors. Among the positive consequences of Carolingian classicism is the careful—if discreet—preservation of the text of Lucretius’s De Rerum Natura, which survives in three valuable ninth-century manuscripts. Whereas rigorous philological studies of these manuscripts have been offered, little attention has been paid to their role in, and connection with, the reception of Lucretius in ninth-century literature. It has been generally assumed that for the Carolingians the DRN was essentially a source for gram…

JaxoDraw: A graphical user interface for drawing Feynman diagrams

2003

JaxoDraw is a Feynman graph plotting tool written in Java. It has a complete graphical user interface that allows all actions to be carried out via mouse click-and-drag operations in a WYSIWYG fashion. Graphs may be exported to postscript/EPS format and can be saved in XML files to be used in later sessions. One of the main features of JaxoDraw is the possibility to produce LaTeX code that may be used to generate graphics output, thus combining the powers of TeX/LaTeX with those of a modern day drawing program. With JaxoDraw it becomes possible to draw even complicated Feynman diagrams with just a few mouse clicks, without the knowledge of any programming language.

2020

The Internet has become one of the main sources of information for university students’ learning. Since anyone can disseminate content online, however, the Internet is full of irrelevant, biased, or even false information. Thus, students’ ability to use online information in a critical-reflective manner is of crucial importance. In our study, we used a framework for the assessment of students’ critical online reasoning (COR) to measure university students’ ability to critically use information from online sources and to reason on contentious issues based on online information. In addition to analyzing students’ COR by evaluating their open-ended short answers, we also investigated the stude…

How bilastine is used to treat allergic rhinitis and urticaria in children

2021

Management guidelines for allergic rhinitis and urticaria recommend oral second-generation antihistamines as first-line treatment. The efficacy and safety of bilastine, the newest nonsedating second-generation antihistamine, are well established in adolescents/adults with these allergic conditions. The bilastine development program for pediatric use (2–<12 years) followed EMA-authorized processes. Pharmacokinetic/pharmacodynamic simulation and modeling and a pharmacokinetic study were conducted to identify and confirm the pediatric dose (10 mg/day). A Phase III, multicenter, double-blind, randomized, placebo-controlled, parallel-group study was performed to confirm the safety of bilasti…

Code civil 1804-2004. Toutes les versions du Code civil depuis deux siècles

2004

1 disque optique numérique (CD-ROM) + 2 p. : pochette cartonnée ill. en coul. ; 12 c; National audience

Uptake of endocytic markers by rice cells: variations related to the growth phase.

2001

Endocytosis is now considered a basic cellular process common to plant cells. Although both non-specific and receptor-mediated endocytosis appear to take place in plant cells, the physiological role of the latter remains unclear. We have investigated the endocytic process in rice cell suspensions using two biotinylated proteins, peroxidase and bovine serum albumin (bHRP and bBSA), as markers. First, we show that markers are internalized by rice cells and appear in intracellular membranes. The uptake of the two markers is temperature dependent, saturable with time and markers dose and it is competed by free biotin. Thus, it shows the properties of a receptor-mediated process. We also show th…

Dissection of keratin dynamics: different contributions of the actin and microtubule systems.

2005

It has only recently been recognized that intermediate filaments (IFs) and their assembly intermediates are highly motile cytoskeletal components with cell-type- and isotype-specific characteristics. To elucidate the cell-type-independent contribution of actin filaments and microtubules to these motile properties, fluorescent epithelial IF keratin polypeptides were introduced into non-epithelial, adrenal cortex-derived SW13 cells. Time-lapse fluorescence microscopy of stably transfected SW13 cell lines synthesizing fluorescent human keratin 8 and 18 chimeras HK8-CFP and HK18-YFP revealed extended filament networks that are entirely composed of transgene products and exhibit the same dynamic…