Search results for "COLON"

NEMATODE COLONIZATION OF PYRITE CINDER-POLLUTED SOIL

2020

The nematofauna was studied in the early stages of a remediation trial at an industrial site where pyrite cinders had accumulated for 40 years in a large area and were then covered with mineral soil. The cinders were contaminated with several metals and metalloids. The soil of the experimental plots was derived from the mixture of cinders with the covering soil in a 1:1 ratio. Plots were amended with manure and sown with 3 metal resistant plants: Sorghum bicolor L., Helianthus annuus L., and Arundo donax L. Samples were taken : a) at the beginning of the trial on the pyrite cinders and covering soil, separately; b) from the mixture before the application of manure; c) from cultivated plots.…

Cirugía del cáncer de colon. Análisis de los resultados en una unidad especializada.

2015

Objetivo: Identificar y correlacionar los factores implicados en los resultados oncológicos en términos de recidiva local y supervivencia en las neoplasias de colon sometidas a cirugía con intención curativa. Método: Análisis retrospectivo de una base de datos prospectiva del Grupo Multidisciplinar del Cáncer Colorrectal de una Unidad especializada. Fueron incluidos en el estudio los pacientes intervenidos con intención curativa, de forma electiva o urgente, de cáncer de colon primario desde enero 1993 hasta diciembre de 2010. Fueron excluidos los pacientes M1. Resultados: Se incluyeron 1277 pacientes (50,9% varones) con una media de edad de 70,2 años. Las neoplasias estaban localizadas: 33…

Les commissions coloniales rattachées au Comité des Travaux historiques et scientifiques

2000

The colonial Commissions connected to the Comité des travaux historiques et scientifiques. In the late nineteenth century, the Comité des travaux historiques et scientifiques became a bigger and bigger research organization, always closely linked to the successive political governments. With each new French conquest, a commission of parisian scientists and local correspondents was created and attached to it, as in 1864, the scientific commission for Mexico, in 1884, the commission for Tunisia, in 1908, the archeological commission for Indochina. The example studied here is that of the commssion for Tunisia, which coordonated researches in archeology and epigraphy in North Africa, thanks to …

Characterizing the collective personality of ant societies: aggressive colonies do not abandon their home.

2011

Animal groups can show consistent behaviors or personalities just like solitary animals. We studied the collective behavior of Temnothorax nylanderi ant colonies, including consistency in behavior and correlations between different behavioral traits. We focused on four collective behaviors (aggression against intruders, nest relocation, removal of infected corpses and nest reconstruction) and also tested for links to the immune defense level of a colony and a fitness component (per-capita productivity). Behaviors leading to an increased exposure of ants to micro-parasites were expected to be positively associated with immune defense measures and indeed colonies that often relocated to other…

No effect of lack of wood for acorn ant colonies development

2021

Acorn ants mostly inhabit cavities in fallen twigs and hollow acorns. Such places, e.g., dead wood, provide an attractive living resource for many groups of microorganisms, like fungi and bacteria, which can be important for ants. However, during experiments in laboratories, acorn ant colonies are typically kept without dead wood. During laboratory experi-ments, the preferences of the ant Temnothorax crassispinus for nest sites with pieces of dead wood were checked, and whether the presence of such wood influenced productivity. In binary choice tests, colonies had to choose a nest site when presented with two potential nest sites, one empty, or two cavities with different contents. The ant …

Comparative Proteomics of Surgical Fragments of Colorectal Cancer with Non-tumoral Mucosa and Associated Liver Metastasis

2013

EFFECT OF miR-21, miR-182 AND let-7i ON TSP-1 EXPRESSION IN COLON CANCER CELL LINE

2010

Background: MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of different genes, including genes involved in cancer progression, angiogenesis and metastasis. Thrombospondin-1 (TSP-1) has been shown to contrast angiogenesis in vivo. TSP-1 expression levels are inversely correlated with tumor vascularity and metastasis in colon cancer. Bio-informatic statistical analysis indicated that TSP-1 is hypothetical target of miR-21, miR-182, overexpressed in CRC, and let-7i which expression is down-regulated in this tumor. In this work we investigated whether TSP-1 expression could be regulated by miR-21, mir-182 and let-7i in HT29 colon cancer cell line. Methods: To investig…

Proteomic profiling and functional characterization of metastatic colon cancer exosomes spreading malignant properties in tumor microenvironment

2016

Human tumors display a remarkable intratumor heterogeneity affecting clinically relevant phenotypes such as ability to metastasize or to tolerate cytotoxic drugs. Recent published data indicate that tumor derived exosomes (TDEs) can have a pivotal role in regulating tumor heterogeneity by transferring functional biomolecules between various populations of tumor cells and between tumor cells and nontumor cells with consequences for whole tumor microenvironment. In this context, our goal was to understand if exosomes derived from highly metastatic cell line may influence the behaviour of less aggressive tumor cells and the properties of endhothelium.

New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy

2020

[EN] Colonic Drug Delivery Systems (CDDS) are especially advantageous for local treatment of inflammatory bowel diseases (IBD). Site-targeted drug release allows to obtain a high drug concentration in injured tissues and less systemic adverse effects, as consequence of less/null drug absorption in small intestine. This review focused on the reported contributions in the last four years to improve the effectiveness of treatments of inflammatory bowel diseases. The work concludes that there has been an increase in the development of CDDS in which pH, specific enzymes, reactive oxygen species (ROS), or a combination of all of these triggers the release. These delivery systems demonstrated a th…

Epithelial NEMO links innate immunity to chronic intestinal inflammation

2007

Deregulation of intestinal immune responses seems to have a principal function in the pathogenesis of inflammatory bowel disease(1-4). The gut epithelium is critically involved in the maintenance of intestinal immune homeostasis-acting as a physical barrier separating luminal bacteria and immune cells, and also expressing antimicrobial peptides(3,5,6). However, the molecular mechanisms that control this function of gut epithelial cells are poorly understood. Here we show that the transcription factor NF kappa B, a master regulator of pro-inflammatory responses(7,8), functions in gut epithelial cells to control epithelial integrity and the interaction between the mucosal immune system and gu…