Search results for "COLON"
showing 10 items of 2038 documents
Molecular analysis on the chemopreventive properties of resveratrol, a plant polyphenol microcomponent.
2002
As a plant microcomponent, resveratrol is a polyphenolic compound produced by several species and found especially in Polygonum roots, peanuts seeds, berries and also grape and therefore can be present in human diet or beverages (red wine, for instance). Traditional chinese medicine and more recent epidemiological studies strongly suggested that resveratrol may act as a cancer chemopreventive compound. The biochemical mechanism by which resveratrol inhibits cell proliferation was provided by studies in numerous human cell lines including our work in hepatoblastoma HepG2 and colorectal tumor SW480 cells. The results show that resveratrol strongly inhibits cell proliferation at the micromolar…
Macrophage MerTK promotes profibrogenic cross-talk with hepatic stellate cells via soluble mediators
2022
Background & aims: Activation of Kupffer cells and recruitment of monocytes are key events in fibrogenesis. These cells release soluble mediators which induce the activation of hepatic stellate cells (HSCs), the main fibrogenic cell type within the liver. Mer tyrosine kinase (MerTK) signaling regulates multiple processes in macrophages and has been implicated in the pathogenesis of non-alcoholic steatohepatitis-related fibrosis. In this study, we explored if MerTK activation in macrophages influences the profibrogenic phenotype of HSCs. Methods: Macrophages were derived from THP-1 cells or differentiated from peripheral blood monocytes towards MerTK+/CD206+/CD163+/CD209- macrophages. Th…
Stimulation of pancreas and gastric carcinoma cell growth by interleukin 3 and granulocyte-macrophage colony-stimulating factor.
1991
Hematopoietic growth factors have recently been well characterized by complementary DNA scloning. For human epidermal growth factor, granulocyte-macrophage colony-stimulating factor recombinant proteins have been expressed in Escherichia coli . To reduce the toxic side effects of chemotherapy on the bone marrow, recombinant human granulocyte-macrophage colony—stimulating factor and recombinant human interleukin 3 were applied to patients suffering of gastrointestinal cancers. To determine the influence of recombinant human granulocyte-macrophage colony—stimulating factor and recombinant human interleukin 3 on human pancreas and gastric cancer cell cells in vitro, a sensitive microculture te…
Interactions between willows and insect herbivores under enhanced ultraviolet-B radiation
2002
We studied the effects of elevated ultraviolet-B radiation on interactions between insect herbivores and their host plants by exposing two species of phytochemically different willows, Salix myrsinifolia and S. phylicifolia, to a modulated increase in ultraviolet radiation in an outdoor experiment and monitoring the colonisation of insect herbivores on these willows. We examined the effect of increased ultraviolet-B (UV-B) radiation on (1) the quality of willow leaves, (2) the distribution and abundance of insect herbivores feeding on these willows, (3) the resulting amount of damage, and (4) the performance of insect larvae feeding on the exposed plant tissue. Six clones of each of the two…
Contatti culturali e identità nel territorio imerese
2009
La dialectique nationalité/citoyenneté : le cas de l’Algérie (XIXe – XXe)
2019
National audience; Les colonisés étaient-ils pleinement Français ? Pleinement citoyens ? Les réponses diffèrent selon les disciplines. En effet, un juriste déclarera impossible de considérer la nationalité par degré : une personne est nationale, étrangère ou apatride. Les colonisés sont tous des nationaux français, il n’y a pas d’alternative. En revanche, un politiste pourra légitimement affirmer que la nationalité des colonisés, en particulier celle des indigènes car ils ne sont pas soumis au Code civil, n’est pas pleine et entière. Sur la notion de citoyen, les disciplines convergent pour déduire du statut des colonisés une discrimination patente débouchant sur des degrés de citoyenneté. …
Moving Localities and Creative Circulation: Travels as Knowledge Production in 18th-Century Europe
2014
In recent historiography of science, circulation has been widely used to weave global narratives about the history of science. These have tended to focus on flows of people, objects and practices rather than investigating the spread of universal patterns of knowledge. The approach has also, to a great extent, concentrated on colonial contexts and treated ‘European science’ as a more or less homogeneous knowledge realm. Furthermore, these studies of circulation have usually been tied to a contextualist view of knowledge formation in which locality is taken as a set of specificities linked with particular locations. In this article we redirect the focus of the discussion on circulation to Eur…
El discurso anticlerical en la construcción de una identidad nacional española republicana (1898-1936)
2002
From the colonial disaster, the anticlericalism was a weapon of the republicans against the Monarchy. In the II Republic old prejudices are emerging just to justify the lay legislation of that moment.<br><br>El anticlericalismo fue un arma de los republicanos contra la Monarquía a partir del desastre colonial. En la II República viejos prejuicios surgen para justificar la legislación laicista del momento.
Multiple approaches to identify bacteria in archaeological waterlogged wood
2013
This study was carried out in collaboration with Soprintendenza del Mare (SM) that started, since 2004, to plan and realize underwater archaeological parks, such as in the Sicilian islands of Pantelleria (Gadir), Levanzo (Cala Minnola), Ustica (Falconiera), Panarea (Basiluzzo) and Filicudi (Capo Graziano). In situ conservation, as well as virtual exhibitions of the same topics, can contribute to ensure the protection and best fruition of underwater cultural heritage. The focus of this study was the identification of bacterial colonies in waterlogged wood samples from the rostrum of a excellent workmanship, that is very likely one of the wrecks attributed to Sextus Pompey fleet (36 BC) and d…