Search results for "COLOR"
showing 10 items of 2721 documents
“Randomized comparison of capecitabine versus fluorouracil/leucovorin in combination with oxaliplatin in metastatic colorectal cancer patients: South…
2008
Valutazione delle caratteristiche morfo-anatomiche di alcune simbiosi micorriziche mediante tecniche colorimetriche usuali e innovative.
2003
Tertiary lymphoid structures in pulmonary metastases of microsatellite stable colorectal cancer
2023
Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates located at sites of chronic inflammation and recognized as prognosticators in several cancers. We aimed to analyse the prognostic effect of TLSs in colorectal cancer (CRC) pulmonary metastases and primary tumours, with a comparison to the CD3+ and CD8+ cell density-based immune cell score (ICS). For TLS density and TLS maximum diameter analysis, 67 pulmonary metastases and 63 primary tumours were stained with haematoxylin and eosin. For ICS scoring and analysis, CD3 and CD8 immunohistochemistry was performed. Excellent interobserver agreement was achieved in all TLS measurements. Of all patients, 36 patients had low TLS den…
Il restauro come pelle: Villa Antonietta a Palermo
2010
ABSTRACT: Tra le moltissime costruzioni Liberty a Palermo, quest’articolo descrive Villa Antonietta, un edificio poco noto e di oscura attribuzione. Di recente è stato realizzato un’intervento di restauro; qui per brevità, si descrivono soltanto alcune questioni legate al tema del colore nel Liberty che in questa Villa sono stati riproposti con principio filologico a partire dalle preesistenze presenti a Mondello dove la Villa ha sede. SUMMERY: Of the many Liberty buildings in Palermo, this article describes Villa Antonietta, a building relatively unknown and of obscure attribution. Recently, restoration work has been undertaken. Here, for the sake of brevity is described solely a few issue…
ShRNA-mediated knock-down of CXCL8 inhibits tumor growth in colorectal liver metastasis.
2018
CXCL8 belongs to proinflammatory chemokines that are predominantly involved in neutrophil chemotaxis and degranulation. Several studies have suggested that secretion of CXCL8 from cancer cells have a profound effect on tumor microenvironment. In this study, in continuation to our previous work of understanding the global picture of invasion related genes in colorectal liver metastases, we clearly show an up-regulation of CXCL8 expression in the tumor cells at the invasion front as compared to the tumor cells in the inner parts of the tumor. Furthermore, ShRNA mediated down-regulation of CXCL8 resulted in inhibition of cell proliferation, viability and invasion in vitro and a near complete g…
Chromogenic detection of nerve agent mimics
2008
The current rise in international concern over criminal terrorist attacks via chemical warfare (CW) agents has resulted in an increasing interest in the detection of these lethal chemicals. Among CW species, nerve agents are extremely dangerous and their high toxicity and ease of production underscore the need to detect these deadly chemicals via quick and reliable procedures. A number of detection systems have been developed, most of them based on enzymatic and physical methodologies. However, these usually show limitations such as low selectivity, lack of portability and a certain complexity in their use. An alternative to these classical methods that has been gaining interest in recent y…
Material Yincana optométrica. Pruebas
2020
Este documento contiene las instrucciones de la primera yincana optométrica realizada en el Grado de Óptica y Optometría. También están las instrucciones de las 6 pruebas llevadas a cabo y la hoja de resultados del alumnado Los dos ficheros adjuntos contienen el mismo material, pero en las dos lenguas oficiales de la Universitat de València, valenciano y castellano. This document contains the instructions for the first optometric gymkhana performed in Optics and Optometry Degree. There are also the instructions for the 6 tests carried out and the student results sheet.We can find these instructions in valenciano and spanish.
Saturation and forward jets in proton-lead collisions at the LHC
2019
We investigate the forward-jet energy spectrum within the Color Glass Condensate framework at 5 TeV center-of-mass energy. In particular, we focus on the kinematic range covered by the CMS-CASTOR calorimeter. We show that our saturation-model calculations are compatible with the CASTOR measurements and that to optimally reproduce the data, effects of multi-parton interactions need to be included. We predict a significant nuclear suppression - reaching down to 50% at the lowest considered jet energies $E_{\rm jet} \sim 500 \, {\rm GeV}$.
Nutrition and lipidomic profile in colorectal cancers
2018
Background: Adherence to a healthy diet has been reported to be essential for the primary prevention of colorectal cancer, through a reduction of tissue inflammation, a low concentration of circulating lipoproteins and lower levels of serum cholesterol. Since an altered expression of the fatty acids pattern has been demonstrated to be a crucial event in colorectal carcinogenesis, lipidomic analysis is considered able to identify early diagnostic and prognostic biomarkers of complex diseases such as colorectal cancer. Methods: cell membrane fatty acid profile and serum lipoproteins pattern were evaluated by gas chromatography and electrophoresis method respectively. Results: There is a close…
An Update on the Role of Anti-EGFR in the Treatment of Older Patients with Metastatic Colorectal Cancer
2022
Although colorectal cancer is increasingly being diagnosed in older patients, their number is largely underrepresented in phase II or III clinical trials. Consequently, guidelines and the SIOG recommendations are not sufficiently clear regarding the treatment of these patients, particularly when chemotherapy is combined with monoclonal antibodies (bevacizumab, cetuximab, and panitumumab). Targeted therapy based on the use of anti-epidermal growth factor receptors (EGFRs) is conditioned by the potential for increased toxicity, making it more difficult to treat an older, rat sarcoma virus (RAS) and B rapidly accelerated fibrosarcoma (BRAF) wild-type patient. In light of a more detailed charac…