Search results for "COLOR"

Extensive transcriptional complexity during hypoxia-regulated expression of the myoglobin gene in cancer.

2013

Recently, the ectopic expression of myoglobin (MB) was reported in human epithelial cancer cell lines and breast tumor tissues, where MB expression increased with hypoxia. The better prognosis of MB-positive breast cancer patients suggested that the globin exerts a tumor-suppressive role, possibly by impairing mitochondrial activity in hypoxic breast carcinoma cells. To better understand MB gene regulation in cancer, we systematically investigated the architecture of the human MB gene, its transcripts and promoters. In silico analysis of transcriptome data from normal human tissues and cancer cell lines, followed by RACE-PCR verification, revealed seven novel exons in the MB gene region, mo…

Historical Building Dating: The Multidisciplinary Study of the Convento de São Francisco (Coimbra, Portugal)

2012

Recognition of polychromatic three-dimensional objects

2004

We propose to use optical multichannel correlation in various chromatic systems to obtain a setup for recognition of polychromatic three-dimensional (3-D) objects based on Fourier-transform profilometry. Because red-green-blue color components are not able to split the luminance information of objects in a defined component, when the 3-D objects are brighter than the reference objects the correlation result gives false alarms. We demonstrate that it is possible to use different color spaces that can split luminance from chromatic information to yield adequate recognition of polychromatic 3-D objects. We show experimental results that prove the utility of the proposed method.

A generalized soil-adjusted vegetation index

2002

Operational monitoring of vegetative cover by remote sensing currently involves the utilisation of vegetation indices (VIs), most of them being functions of the reflectance in red (R) and near-infrared (NIR) spectral bands. A generalized soil-adjusted vegetation index (GESAVI), theoretically based on a simple vegetation canopy model, is introduced. It is defined in terms of the soil line parameters (A and B) as: GESAVI=(NIRBRA)/(R+Z), where Z is related to the red reflectance at the cross point between the soil line and vegetation isolines. As Z is a soil adjustment coefficient, this new index can be considered as belonging to the SAVI family. In order to analyze the GESAVI sensitivity to s…

Corresponding-pair procedure: a new approach to simulation of dichromatic color perception.

2004

The dichromatic color appearance of a chromatic stimulus T can be described if a stimulus S is found that verifies that a normal observer experiences the same sensation viewing S as a dichromat viewing T. If dichromatic and normal versions of the same color vision model are available, S can be computed by applying the inverse of the normal model to the descriptors of T obtained with the dichromatic model. We give analytical form to this algorithm, which we call the corresponding-pair procedure. The analytical form highlights the requisites that a color vision model must verify for this procedure to be used. To show the capabilities of the method, we apply the algorithm to different color vi…

Ocher and cinnabar in the argaric funerary record

2012

The known cases of Bronze Age Argaric stained skeletons found in the Southeast of the Iberian Peninsula, have been analysed. The various hypotheses proposed relating to the origin of these colorations have been evaluated in light of new data provided by SEM, XRD and RAMAN spectroscopic analysis carried out on five Argaric graves of Murcia and Alicante. The results have indicated the presence of ochre and cinnabar on some of the skeletons. Without discarding the possibility that both substances were used in dyeing fabrics, it is proposed that their main use was for face and body make-up, being higher the number of recorded cases on female skeletons compared to male.

The genomic history of the Aegean palatial civilizations

2021

Summary The Cycladic, the Minoan, and the Helladic (Mycenaean) cultures define the Bronze Age (BA) of Greece. Urbanism, complex social structures, craft and agricultural specialization, and the earliest forms of writing characterize this iconic period. We sequenced six Early to Middle BA whole genomes, along with 11 mitochondrial genomes, sampled from the three BA cultures of the Aegean Sea. The Early BA (EBA) genomes are homogeneous and derive most of their ancestry from Neolithic Aegeans, contrary to earlier hypotheses that the Neolithic-EBA cultural transition was due to massive population turnover. EBA Aegeans were shaped by relatively small-scale migration from East of the Aegean, as e…

Expression of stress protein gp96, a tumor rejection antigen, in human colorectal cancer

2000

Preparations of stress protein gp96 from tumor cells are active as tumor vaccines by eliciting immune responses against mixtures of individual tumor peptide antigens which are complexed to gp96. Due to the individual antigenicity of tumors, a vaccine consisting of tumor-derived gp96 has to be prepared individually for each patient from autologous tumor tissue. So far, gp96 expression by human tumors has not been analyzed. Here, we report stable and mostly homogenous expression of gp96 by colorectal cancer, which was enhanced compared to surrounding tumor stroma in 70% to 80% of colorectal cancer specimens. Fewer non-metastatic than metastatic primary cancer specimens showed enhanced gp96 ex…

Color choice behavior in cats and the effect of changes in the color of the illuminant.

1993

Endothelial VEGFR-3 expression in colorectal carcinomas is associated with hematogenous metastasis

2009

Vascular endothelial growth factor receptor 3 (VEGFR-3) is a major inducer of lymphangiogenic signalling and seems to be involved also in angiogenesis. Since both processes are closely linked with tumor metastasis this study investigated the expression of VEGFR-3 in tumor-associated vessels in colorectal carcinomas and evaluated its relevance for lymphogenous and hematogenous metastasis. In a comparative study between microvascular endothelial cells isolated from the tumor (HCTEC) and the corresponding non-neoplastic tissue (HCMEC) from five patients with colorectal cancer VEGFR-3 expression was measured using a specific ELISA. The expression pattern was individually different, with cases s…