Search results for "COLOR"

Quantification of cranial convergences in arvicolids (Rodentia)

1997

Cranial convergence in nine species of arvicolids is quantified phenetically using geometric morphometry. In a preliminary step, a hypothesis about phyletic relationships is proposed as a framework against which to examine morphological comparisons. The cranial morphology is then depicted in three series of 37, 20 and 13 landmarks characterizing the lower, upper and lateral sides of the skull respectively. Superimposition (Procrustes) methods are used to quantify shape differences and establish phenograms for the three sides of the skull. The phenogram obtained for lateral sides reveals a strong connection between skull profile and mode of life: surface dwelling forms have elongated skulls …

P008 Differences in macrophage infiltration and Wnt ligands expression between stricturing and penetrating behaviour in Crohn’s disease

2018

Classes of Colors and Timbres: A Clustering Approach

2022

Similarities between different sensory dimensions can be addressed considering common “movements” as causes, and emotional responses as effects. An imaginary movement toward the “dark” produces “dark sounds” and “dark colors,” or, toward the “bright,” “brighter colors” and “brighter sounds.” Following this line of research, we draw upon the confluence of mathematics and cognition, extending to colors and timbres the gestural similarity conjecture, a development of the mathematical theory of musical gestures. Visual “gestures” are seen here as paths in the space of colors, compared with paths in the space of orchestral timbres. We present an approach based on clustering algorithm to evaluate…

“The Right Amount of Odd”: Vocal Compulsion, Structure, and Groove in Two Love Songs from Around the World in a Day

2020

In this music-analytic interpretation of two love songs from Prince’s Around the World in a Day album, we investigate the properties of groove, arrangement, and vocality, all of which contribute to the artist’s inimitable signature. With a disciplinary grounding in musicology, we demonstrate ways whereby musical features are associated with meaning in recorded songs. Underlying the approach is the notion that it is in the music where Prince’s ingenuity mainly lies. The analysis is informed by an understanding of the technological ramifications of the process on the part of Prince and his audio engineer Susan Rogers.

KOMUNIKASI NIKLAS LUHMANN DALAM MEMBANGUN KERUKUNAN ANTAR UMAT BERAGAMA DI WILAYAH PERKOTAAN

2020

Religious plurality in the era of globalization is a necessity in the midst of cultural heterogeneity, religious expression and religion itself. Religious plurality has a very large potential and role in the process of integrating the development of the Indonesian nation in the future. However, on the other hand, religious plurality contains the potential for conflict and disintegration of the nation, because the dominance of the absolute truth claims of each religion so that emotions become the basis of interaction and communication. Therefore, communication becomes a pillar of religious harmony. To achieve religious harmony, this research uses a qualitative-descriptive method that puts wi…

Antitumoral activity of curcumin: an adjuvant therapeutic strategy

2021

Curcumin, an active substance contained in an Indian spice called turmeric or curcuma, is well known for its anti-inflammatory and antioxidant properties. In recent times, it was taken into account and studied as an antitumoral molecule, by relying on its interference on several biological mechanisms, such as the inhibition of inflammatory mediators, the enhancement of detoxifying enzymes’ action and processes of cell growth and proliferation. Studies show how the high dosage of curcumin in vitro inhibits colorectal tumor cells, pancreatic tumor cells, lung cancer cells and glioblastoma’s cells, interfering in signaling pathways as Wnt/β-catenin, NF-kB and PI3K/Akt and leading to cell cycle…

The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models

2014

AbstractIn spite of the novel strategies to treat colon cancer, mortality rates associated with this disease remain consistently high. Tumour recurrence has been linked to the induction of resistance towards chemotherapy that involves cellular events that enable cancer cells to escape cell death. Treatment of colon cancer mainly implicates direct or indirect DNA-damaging agents and increased repair or tolerances towards subsequent lesions contribute to generate resistant populations. Resveratrol (RSV), a potent chemosensitising polyphenol, might share common properties with chemotherapeutic drugs through its indirect DNA-damaging effects reported in vitro. In this study, we investigated how…

Chemotherapy Sensitizes Colon Cancer Initiating Cells to Vγ9Vδ2 T Cell-Mediated Cytotoxicity

2013

Colon cancer comprises a small population of cancer initiating stem cells (CIC) that is responsible for tumor maintenance and resistance to anti-cancer therapies, possibly allowing for tumor recapitulation once treatment stops. Combinations of immune-based therapies with chemotherapy and other anti-tumor agents may be of significant clinical benefit in the treatment of colon cancer. However, cellular immune-based therapies have not been experimented yet in the population of colon CICs. Here, we demonstrate that treatment with low concentrations of commonly used chemotherapeutic agents, 5- fluorouracyl and doxorubicin, sensitize colon CICs to Vc9Vd2 T cell cytotoxicity. Vc9Vd2 T cell cytotox…

γδ T cells as a potential tool in colon cancer immunotherapy

2014

γδ T cells are capable of recognizing tumor cells and exert potent cellular cytotoxicity against a large range of tumors, including colon cancer. However, tumors utilize numerous strategies to escape recognition or killing by patrolling γδ T cells, such a downregulation of NKG2D ligands, MICA/B and ULBPs. Therefore, the combined upregulation of T-cell receptorand NKG2D ligands on tumor cells and induction of NKG2D expression on γδ T cells may greatly enhance tumor killing and unlock the functions of γδ T cells. Here, we briefly review current data on the mechanisms of γδ T-cell recognition and killing of colon cancer cells and propose that γδ T cells may represent a promising target for the…

The Diapause Lipidomes of Three Closely Related Beetle Species Reveal Mechanisms for Tolerating Energetic and Cold Stress in High-Latitude Seasonal E…

2020

During winter insects face energetic stress driven by lack of food, and thermal stress due to sub-optimal and even lethal temperatures. To survive, most insects living in seasonal environments such as high latitudes, enter diapause, a deep resting stage characterized by a cessation of development, metabolic suppression and increased stress tolerance. The current study explores physiological adaptations related to diapause in three beetle species at high latitudes in Europe. From an ecological perspective, the comparison is interesting since one species (Leptinotarsa decemlineata) is an invasive pest that has recently expanded its range into northern Europe, where a retardation in range expa…