Search results for "COMPLICATIONS"

showing 10 items of 1529 documents

Expression of p63, p53 and ki-67 in patients with cervical intraepithelial neoplasia

2017

Objective: Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries a risk of progression to cervical cancer. The aim of this study was to compare expression of three biomarkers named p53, p63 and Ki-67 in patients with various grades of cervical intraepithelial neoplasia and in a control group. Material and Method: 58 patients were enrolled in the study. Each patient underwent a colposcopy-guided biopsy of the cervix. Immunostaining for markers (p53, p63 and Ki-67) was performed on tissue samples of normal cases (n=10), CIN I (n=20), CIN II (n=14), and CIN III (n=14). Results: Our study showed a significant increase of the expression of t…

p530301 basic medicineUterine Cervical Neoplasmsurologic and male genital diseasesGastroenterology0302 clinical medicineYoung adultCervical cancerp63medicine.diagnostic_testbiologyvirus diseasesMiddle AgedImmunohistochemistryfemale genital diseases and pregnancy complicationsKoilocytesurgical procedures operativemedicine.anatomical_structure030220 oncology & carcinogenesisKi-67Disease ProgressionKi-67ImmunohistochemistryFemalelcsh:RB1-214Adultmedicine.medical_specialtyAdolescentCervical intraepithelial neoplasiaPathology and Forensic MedicineYoung Adult03 medical and health sciencesInternal medicineBiopsyBiomarkers Tumorlcsh:PathologymedicineHumansneoplasmsCervixCervical intraepithelial neoplasiabusiness.industryMembrane ProteinsUterine Cervical Dysplasiamedicine.diseaseKi-67 Antigen030104 developmental biologybiology.proteinTumor Suppressor Protein p53businessTurkish Journal of Pathology
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Antitumor Effect of Cabozantinib in Bone Metastatic Models of Renal Cell Carcinoma

2021

Background: The presence of bone metastases in renal cell carcinoma (RCC) negatively affects patients’ survival. Data from clinical trials has highlighted a significant benefit of cabozantinib in bone metastatic RCC patients. Here, we evaluated the antitumor effect of cabozantinib in coculture models of renal cell carcinoma (RCC) and osteoblasts (OBs) to investigate whether and how its antiproliferative activity is influenced by OBs. Methods: Bone/RCC models were generated, coculturing green fluorescent protein (GFP)-tagged Caki-1 and 786-O cells with human primary OBs in a “cell–cell contact” system. RCC proliferation and the OB molecular profile were evaluated after the cabozantinib treat…

renal cell carcinomaCabozantinibQH301-705.5Biologyurologic and male genital diseasesGeneral Biochemistry Genetics and Molecular BiologyArticleGreen fluorescent proteinchemistry.chemical_compoundCabozantinib; Osteoblasts; Renal cell carcinomaRenal cell carcinomacabozantinibmedicineBiology (General)Antitumor activityGeneral Immunology and MicrobiologyCell growthOsteoblastosteoblastsmedicine.diseasefemale genital diseases and pregnancy complicationsInhibitory potencychemistryCancer researchMolecular ProfileGeneral Agricultural and Biological SciencesBiology
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Maintenance of anticoagulant and antiplatelet agents for patients undergoing vitreoretinal surgery

2009

International audience; Purpose: To establish the prevalence of anticoagulant, aspirin, and clopidogrel use in patients undergoing vitreoretinal surgery, and to compare the outcome of peribulbar anesthesia between users and non-users. Materials and Methods: We conducted a retrospective case series in one academic center between January and June 2009. We analyzed the chart of 239 eyes who underwent posterior segment surgery with peribulbar anesthesia. Data included age, reasons for anticoagulant and/or antiplatelet agents, operative procedure, history of diabetes mellitus, high blood pressure, axial globe length, pre and post operative visual acuity, complications rates during and after anes…

retina[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologygenetic structures[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organsclinical (human) or epidemiologic studies: outcomes/complications[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organsvitreoretinal surgeryeye diseases[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Double blind randomized clinical trial comparing minimally- invasive envelope flap and conventional envelope flap on impacted lower third molar surge…

2022

The latest trend in surgery is to look for minimally invasive procedures, with fewer complications and a shorter recovery time. This study aims to compare the minimally- invasive envelope flap, with smaller incision and fewer dissection and the conventional envelope flap, with a 20mm incision, on impacted mandibular third molar surgery, focusing on the hypothesis that there were no differences in postoperative outcomes. A double-blind randomized clinical trial was designed to compare both incisions, focused on determining the approach with minor postoperative side-effects and minor impact on quality-of-life. A total of 60 patients were enrolled for the study if their presented impacted mand…

salivaPain Postoperativetranscultural validationAdolescentTooth ImpactedMandiblexerostomia questionnairePostoperative ComplicationsOtorhinolaryngologyTooth ExtractionQuality of LifeHumansEdemahead and neck cancerMolar ThirdTrismusSurgeryxerostomiaGeneral DentistryradiotherapyUNESCO:CIENCIAS MÉDICASMedicina Oral Patología Oral y Cirugia Bucal
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Complicanze delle fatture dello scafoide carpale

2016

Le fratture dello scafoide carpale sono relativamente rare e avvengono soprattutto nei giovani in seguito a traumi ad alta energia. Per via della sua particolare conformazione anatomica e per la sua vascolarizzazione, è importante un’attenta valutazione del tipo di frattura per individuare il più corret- to approccio terapeutico, al ne di prevenire le non rare complicanze quali: ritardo di consolidazione, viziosa consolidazione e pseudoartrosi. Diverse sono le classi cazioni delle fratture e delle pseudoartrosi proposte da vari autori, le quali convergono sull’importanza della valutazione della stabilità dei frammenti. Le fratture di scafoide stabili bene ciano in genere di un trattamento i…

scaphoid nonunion complicationsSettore MED/33 - Malattie Apparato Locomotorescafoide pseudoartrosi complicanze
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Graves’ disease

2017

stimulating antibodiesmedicine.medical_specialtyfunctional TSH receptor antibodiesEndocrinology Diabetes and MetabolismGraves' disease030209 endocrinology & metabolismHyperthyroidismAntibodiesDiagnosis DifferentialIodine Radioisotopes03 medical and health sciencesEndocrinology0302 clinical medicineAntithyroid AgentsPregnancyInternal medicineBlocking antibodyHumansMedicineNomenclatureGeneral Commentarybusiness.industryRemission InductionReceptors Thyrotropinmedicine.diseaseGraves DiseaseAnti-thyroid autoantibodiesCausalityPregnancy Complicationsblocking antibodiesEndocrinology030220 oncology & carcinogenesisImmunologyTSH receptor antibodyThyroidectomyFemalenomenclatureGraves’ diseasebusinessFrontiers in Endocrinology
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Clinical Behavior of Ceramic, Hybrid and Composite Onlays. A Systematic Review and Meta-Analysis

2020

A systematic review and meta-analysis was performed to analyze the survival of onlay restorations in the posterior region, their clinical behavior according to the material used (ceramic reinforced with lithium disilicate, conventional feldspathic ceramic or reinforced with leucite; hybrid materials and composite), possible complications, and the factors influencing restoration success. The systematic review was based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement, without publication date or language restrictions. An electronic search was made in the PubMed, Scopus, Embase, and Cochrane databases. After discarding duplicate publications and stu…

survival rateCeramicscomplicationsHealth Toxicology and Mutagenesisclinical evaluationPopulationPosterior regionhybrid dental materialDentistrylcsh:MedicineReviewComposite Resins03 medical and health sciences0302 clinical medicineQualitative analysis0502 economics and businessLithium disilicateMedicineHumanscompositeDental Restoration FailureeducationSurvival rateeducation.field_of_studybusiness.industry05 social scienceslcsh:RPublic Health Environmental and Occupational Health030206 dentistryFeldspathic ceramicposterior partial restorationsSystematic reviewInlaysMeta-analysisonlays050211 marketingbusinessInternational Journal of Environmental Research and Public Health
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Complications of ambulatory oral surgery in patients over 65 years of age

2004

En los pacientes mayores de 65 años es común la presencia de enfermedades sistémicas graves como la hipertensión arterial, accidentes cerebrovasculares, enfermedades cardíacas, diabetes mellitus y las enfermedades mentales, lo que conlleva que consuman diversos tipos de medicamentos para su tratamiento. Este hecho puede repercutir sobre la salud bucodental de estos pacientes y hay que tenerlas en cuenta a la hora de efectuar cualquier tratamiento odontológico. Se ha realizado un estudio retrospectivo en 196 pacientes mayores de 65 años para constatar qué tipo de tratamiento quirúrgico se practicó en ámbito ambulatorio bajo anestesia locorregional valorando la presencia de patología sistémic…

tratamiento quirúrgico-ambulatorioCirurgia oralcomplicacionesAmbulatory surgeryComplications (Medicine)Odontología:CIENCIAS MÉDICAS [UNESCO]OdontologiaCiencias de la saludPersones gransPaciente geriátricoComplicacions (Medicina)Oral surgeryCirurgia ambulatòriaDentistryUNESCO::CIENCIAS MÉDICASOlder people
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Incidencia, factores de riesgo y significado pronóstico de la proteinuria en el trasplante renal. Valor predictivo de la proteinuria precoz sobre la …

2010

La proteinuria es el principal marcador independiente de progresión de enfermedad renal en riñones nativos. En el trasplante renal es indicativa de lesión renal a nivel glomerular y tubulointersticial, y se ha relacionado con una peor supervivencia del injerto y del paciente. No obstante, existen pocas evidencias acerca del papel pronóstico y predictivo de la proteinuria en el trasplante renal, sobre todo en lo que respecta a la proteinuria precoz y de bajo grado. En este trabajo de investigación se ha intentado profundizar en el conocimiento de la proteinuria en nuestra población trasplantada renal que incluye una elevada prevalencia de trasplantes con órganos de donantes con criterios exp…

urogenital systemFacultat de Medicina617urologic and male genital diseasesCirurgia. Ortopèdia. Oftalmologiafemale genital diseases and pregnancy complications
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Tema 12-AP especial

2020

Tema 12-Patologia renal inflamatòria glomerular

urogenital systemUNESCO::CIENCIAS MÉDICASurologic and male genital diseasesfemale genital diseases and pregnancy complications
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