Search results for "COMPUTED TOMOGRAPHY"
showing 10 items of 713 documents
Cardiac Micro–Computed Tomography Imaging of the Aging Coronary Vasculature
2012
Background— Alterations at the level of the coronary circulation with aging may play an important role in the evolution of age-associated changes in left ventricular (LV) fibrosis and function. However these age-associated changes in the coronary vasculature remain poorly defined primarily due to the lack of high resolution imaging technologies. The current study was designed to utilize cardiac micro–computed tomography (micro-CT) technology as a novel imaging strategy, to define the 3-dimensional coronary circulation in the young and aged heart and its relationship to LV fibrosis and function. Methods and Results— Young (2 months old; n=10) and aged (20 months old; n=10) Fischer rats unde…
Die nächste Generation „atypischer” Antipsychotika: Der Beitrag der Positronenemissionstomographie
2003
Almost fifteen years of research with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) have led to a profound understanding of the relationships between antipsychotic doses and plasma levels on the one hand and occupancy of (striatal) D 2 -like dopamine receptors on the other hand as well as with the associated clinical effects and side effects. Furthermore, with the development of clinically atypical" antipsychotics PET studies helped to generate hypotheses regarding the essential pharmacological properties of this heterogeneous class of drugs. Possible mechanisms of action include combined D 2 -/5-HT 2 antagonism, preferential mesolimbic binding, a…
Results from burial experiments with simulated medieval glasses
2002
ABSTRACTDuring several hundred years of burial in the soil, glasses, especially those with medieval compositions, develop heavily corroded surfaces, showing phenomena such as local pitting, laminated layers and browning effects. For this study the damage phenomena have been characterised for three original glasses, using conventional methods (light microscopy and SEM of the surface and cross sections) and microfocus X-ray computed tomography (mCT), a new non-destructive analytical technique.The degradation of glass in the soil depends on a variety of parameters, concerned with the glass itself and with the burial environment. Since synergetic effects may complicate any mechanistic studies, …
Systemic schistosomiasis and large bowel perforation: An unexpected surgical urgency. Report of a case and literature review
2019
Key Clinical Message In the presence of suggestive clinical picture (high eosinophil count and multiple CT scan granuloma‐like lesions), schistosomiasis should be taken into account in case of suspected bowel perforation even if common risk factors are not identified through anamnesis.
Total occlusion of aortic arch in a 62-year-old man presenting with acute myocardial infarction
2011
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Assessment of Thoracic Aortic Dimensions in an Experimental Setting: Comparison of Different Unenhanced Magnetic Resonance Angiography Techniques Wit…
2008
PURPOSE To compare different unenhanced magnetic resonance angiography (MRA) techniques for quantitative evaluation of vessel lumen in an experimental setting in young pigs whose dimensions allow for a comparison with a pediatric population. MATERIAL AND METHODS Magnetic resonance imaging was performed in 5 healthy ventilated pigs at 1.5 T. Three different electrocardiogram (ECG)-triggered sequences were applied for MRA: [TSE-Db] T2-weighted dark-blood TurboSpinEcho (2.0 x 1.1 x 4 mm3); [trueFISP] 2D-steady-state-free-precession (2.2 x 1.8 x 2 mm3); [NAV] respiratory-gated, T2-prepared 3D-trueFISP (1.3 x 1.3 x 1.3 mm3). ECG-gated-CT angiography (CTA) (16-row CT, 1 mm collimation) served as …
In Silico Shear and Intramural Stresses are Linked to Aortic Valve Morphology in Dilated Ascending Aorta
2017
Objective/Background: The development of ascending aortic dilatation in patients with bicuspid aortic valve (BAV) is highly variable, and this makes surgical decision strategies particularly challenging. The purpose of this study was to identify new predictors, other than the well established aortic size, that may help to stratify the risk of aortic dilatation in BAV patients.Methods: Using fluid-structure interaction analysis, both haemodynamic and structural parameters exerted on the ascending aortic wall of patients with either BAV ( n = 21) or tricuspid aortic valve (TAV; n = 13) with comparable age and aortic diameter (42.7 +/- 5.3 mm for BAV and 45.4 +/- 10.0 mm for TAV) were compared…
TAVI imaging: over the echocardiography
2020
Aortic valve stenosis (AS) is a common valvular heart disease. Recently, transcatheter aortic valve implantation (TAVI) has changed the treatment of severe AS in elderly patients with contraindications to traditional surgical replacement. Echocardiography is conventionally used as the first imaging modality to assess the presence and severity of AS and to provide anatomical and functional information. Nowadays, imaging techniques play a crucial role in the planning of TAVI to define suitable candidates. Computed tomography (CT) is essential to display the anatomy of the aortic valve complex (including aortic annulus, Valsalva sinuses, coronary arteries ostia, sinotubular junction), thoracoa…
X-ray computed tomography investigations of Cucuteni ceramic statuettes:
2013
Deciphering the internal structure of prehistoric artefacts can provide spectacular insights that might help us understand the people who made them. In order to preserve the integrity of these relics of past civilisations, it is desirable to make such investigations using non-destructive techniques. Recent decades have witnessed a growth in the X-ray computed tomography (CT) applications in the study of cultural heritage objects. This paper presents and discusses tomographic investigations of two Cucuteni ceramic statuettes discovered in Romania. The study was made with a CT device specially designed for archaeometric applications.
The Protohistoric sword from Le Gué-de-Velluire (Vendée, France): a pasticcio's history unveiled by archaeometrical research
2020
International audience; The Gué-de-Velluire sword (Vendée, France) is part of the Rochebrune collection collected during the 19 th and the 20 th centuries and now preserved in the Dobrée Museum in Nantes (Loire-Atlantique, France). The unusual shape of its hilt, its uncorroded rivets and the rather uncommon combination of a bronze grip with an iron blade made this sword an exceptional object. It has been depicted in a large number of papers since the 20 th century, but the question of its authenticity has hardly ever been tackled. New analyses performed with the support of the Dobrée Museum, the Arc'Antique laboratory and Ghent University delivered new data enabling us to discuss this delic…