Search results for "CONSORT"

The Incubation Process for the Creation of Viable Firms: The Case of ARCA Consortium

2013

Purpose of the study. The process of creation of new firms is particularly complex when it starts from very innovative ideas that may be not understood by the stakeholders of the firm. The aim of this study is to demonstrate that academic incubators play a key role for firms’ viability. Methodology. We analyze the effectiveness of the incubation process that takes place in the incubator of Consorzio Arca, by means of a single case study with embedded design. Findings. The effectiveness of the incubation process is demonstrated by the high number of spin-offs that, after incubation, are able to stand alone in the market and to find the consonance with the relevant supra-systems. Research lim…

Festivas demostraciones, con que celebró la ... ciudad de Alicante, los reales desposorios de su Magestad, con ... Doña Isabel Farnesse de Neoburg,…

1715

Sig. A6 Port. orlada. - Reclams. - Capital grav., banda i ornament tip. floral al final

Festivas demostraciones, con que celebró la ... ciudad de Alicante, los reales desposorios de su Magestad, con ... Doña Isabel Farnesse de Neoburg, P…

Sig. A6 Port. orlada. - Reclams. - Capital grav., banda i ornament tip. floral al final

Nueva relacion en un curioso romance, que refiere y declara las plausibles y solemnes fiestas reales de toros y cañas, que se delebraron en esta ... …

Peu d'impremta pres del colofó Data d'impressió deduïda del títol Text a dues columnes Signatures: [ ]2 Escut real xilogràfic en pàgina [1

Microbial Dynamics between Yeasts and Acetic Acid Bacteria in Kombucha: Impacts on the Chemical Composition of the Beverage.

2020

Kombucha is a traditional low-alcoholic beverage made from sugared tea and transformed by a complex microbial consortium including yeasts and acetic acid bacteria (AAB). To study the microbial interactions and their impact on the chemical composition of the beverage, an experimental design with nine couples associating one yeast strain and one AAB strain isolated from original black tea kombucha was set up. Three yeast strains belonging to the genera Brettanomyces, Hanseniaspora, and Saccharomyces and three strains of Acetobacter and Komagataeibacter species were chosen. Monocultures in sugared tea were analyzed to determine their individual microbial behaviors. Then, cultivation of the ori…

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs.

2021

[BACKGROUND & AIMS] Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intra-hepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response to licensed medications, motivating the search for novel therapies. Previous genome-wide association studies (GWAS) and meta-analyses (GWMA) of PBC have identified numerous risk loci for this condition, providing insight into its aetiology. We undertook the largest GWMA of PBC to date, aiming to identify additional risk loci and prioritise candidate genes for in silico drug efficacy screening. [METHODS] We combined new and existing genotype data for 10, 516 cases and 20, 77…

Reales festejos, que Madrid executó, en celebridad de los gloriosos casamientos de los serenissimos señores, principe nuestro señor, y señora infanta…

1722

Port. orlada Sig.: [ ]1, A8, [ ]1 Reclams

An Efficient and Secure Energy Trading Approach with Machine Learning Technique and Consortium Blockchain

2022

In this paper, a secure energy trading mechanism based on blockchain technology is proposed. The proposed model deals with energy trading problems such as insecure energy trading and inefficient charging mechanisms for electric vehicles (EVs) in a vehicular energy network (VEN). EVs face two major problems: finding an optimal charging station and calculating the exact amount of energy required to reach the selected charging station. Moreover, in traditional trading approaches, centralized parties are involved in energy trading, which leads to various issues such as increased computational cost, increased computational delay, data tempering and a single point of failure. Furthermore, EVs fac…

DNA methylation in childhood asthma

2018

Background: DNA methylation profiles associated with childhood asthma might provide novel insights into disease pathogenesis. We did an epigenome-wide association study to assess methylation profiles associated with childhood asthma. Methods: We did a large-scale epigenome-wide association study (EWAS) within the Mechanisms of the Development of ALLergy (MeDALL) project. We examined epigenome-wide methylation using Illumina Infinium Human Methylation450 BeadChips (450K) in whole blood in 207 children with asthma and 610 controls at age 4–5 years, and 185 children with asthma and 546 controls at age 8 years using a cross-sectional case-control design. After identification of differentially m…

Genome-wide associations for birth weight and correlations with adult disease

2016

Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in observational studies is reproducibly associated with future risk of adult metabolic diseases including type 2 diabetes (T2D) and cardiovascular disease. These life-course associations have often been attributed to the impact of an adverse early life environment. Here, we performed a multi-ancestry genome-wide association study (GWAS) meta-analysis of BW in 153,781 individuals, identifying 60 loci where fetal genotype was associated with BW (P < 5 × 10(-8)). Overall, approximately 15% of variance in BW was captured by assays of fetal genetic variation. Using genet…