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showing 10 items of 1003 documents

A European multicentre photopatch test study

2012

The two most common agent groups currently responsible for photoallergic contact dermatitis (PACD) are organic ultraviolet (UV) absorbers in sunscreens and topical nonsteroidal anti-inflammatory drugs (NSAIDs). However, availability of information on the photoallergenic potential of these agents is scarce.To obtain current information on the frequency of PACD to 19 organic UV absorbers and five topical NSAIDs, including newer agents, in common usage in Europe.A prospective, multicentre photopatch test study was conducted with 1031 patients attending for investigation of suspected PACD in 30 centres across 12 European countries.A total of 346 PACD reactions in 200 (19·4%) subjects occurred. …

AdultMalemedicine.medical_specialtyAdolescentUltraviolet RaysPhotopatch testPhotoallergic Contact DermatitisSunscreening AgentsDermatologyYoung AdultmedicineHumansProspective StudiesYoung adultProspective cohort studyAgedAged 80 and overPhotosensitizing AgentsDermatitis Photoallergicbusiness.industryAnti-Inflammatory Agents Non-SteroidalPhotosensitizing AgentMiddle AgedPatch TestsDermatologySurgeryEuropePhotoallergensFemalebusinessSunscreening AgentsBritish Journal of Dermatology
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Simultaneous sodium lauryl sulphate testing improves the diagnostic validity of allergic patch tests. Results from a prospective multicentre study of…

2005

Summary Background  There is evidence that a higher skin susceptibility may induce nonspecific erythematous or weak positive reactions to contact allergens in patch testing. Objectives  To evaluate whether simultaneous application of sodium lauryl sulphate (SLS) along with diagnostic patch tests with contact allergens can provide information regarding skin irritability which may help to discriminate allergic from nonspecific irritant reactions to contact allergens. Methods  Between July 2001 and June 2003, this prospective study collected patch test data of 5971 patients from 19 centres in Germany and Austria in the Information Network of Departments of Dermatology (IVDK). In addition to co…

AdultMalemedicine.medical_specialtyAllergyPathologyErythemaCocamidopropyl betaineDermatologymedicine.disease_causeDermatitis ContactDermatitis AtopicDiagnosis Differential030207 dermatology & venereal diseases03 medical and health sciencesBenzalkonium chloridechemistry.chemical_compound0302 clinical medicineAllergenPredictive Value of TestsMedicineHumansProspective StudiesDiagnostic Errorsintegumentary systembusiness.industryPatch testSodium Dodecyl SulfateAllergensPatch Testsmedicine.diseaseDermatology3. Good healthchemistryDermatitis OccupationalErythema030220 oncology & carcinogenesisDermatitis Allergic ContactFemalemedicine.symptomIrritationbusinessContact dermatitismedicine.drugThe British journal of dermatology
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Late reactions to patch test preparations with reduced concentrations of p-phenylenediamine : a multicentre investigation of the German Contact Derma…

2011

Background. p-Phenylenediamine (PPD) 1% in petrolatum has been shown in a prospective study to elicit late reactions in 1.5% of routine patch tests, which may be indicative of patch test sensitization. Objectives. To assess the frequency of late reactions to reduced PPD patch test concentrations. Methods. In 1838 patients, PPD was tested at three concentrations (0.5% pet., group I; 0.4% pet., group II; and 0.35% pet., group III). Patch tests were read on D1 (D2) to D3 (D4); additional late readings were performed on D7, D14, and D21. Patients who were not able to return for all scheduled late readings were telephoned on D7, D14, and D21, and questioned about a reaction at the patch test sit…

AdultMalemedicine.medical_specialtyAllergyTime FactorsMedizinDermatologyPhenylenediaminesGastroenterology030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compoundYoung Adult0302 clinical medicineImmunopathologyInternal medicineImmunology and AllergyMedicineHumans030212 general & internal medicineProspective cohort studySensitizationbusiness.industryPatch testp-PhenylenediamineMiddle AgedPatch Testsmedicine.disease3. Good healthSurgerymedicine.anatomical_structurechemistryPatch test sensitizationDermatitis Allergic ContactFemalebusinessContact dermatitis
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Effect of custom-made and prefabricated insoles on plantar loading parameters during running with and without fatigue.

2014

Controversy exists whether custom-made insoles are more effective in reducing plantar loading compared to prefabricated insoles. Forty recreational athletes ran using custom-made, prefabricated, and the original insoles of their running shoes, at rest and after a fatigue run. Contact time, stride rate, and plantar loading parameters were measured. Neither the insole conditions nor the fatigue state modified contact time and stride rate. Addressing prevention of running injuries, post-fatigue loading values are of great interest. Custom-made insoles reduced the post-fatigue loading under the hallux (92 vs. 130 kPa, P0.05), medial midfoot (70 vs. 105 kPa, P0.01), and lateral midfoot (62 vs 96…

AdultMalemedicine.medical_specialtyContact timeRestSTRIDEPhysical Therapy Sports Therapy and RehabilitationRunningSports EquipmentPhysical medicine and rehabilitationPressureMedicineHumansOrthopedics and Sports MedicineFoot OrthosesFatiguebusiness.industryRunning injuriesFootEquipment DesignShoesGait analysisAthletic InjuriesFemaleStress MechanicalbusinessJournal of sports sciences
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Confidentiality and disclosure of HIV infection: HIV-positive persons' experience with HIV testing and coping with HIV infection in Latvia.

2000

The objective of the study was to explore retrospectively HIV-infected individuals experience with HIV testing counseling and the issue of confidentiality in the Latvian context. A qualitative study using grounded theory approach and based on semi-structured in-depth interviews was implemented. 13 HIV-positive individuals above 18 were selected using purposeful sampling from the 63 HIV-positive individuals registered in Latvia between 1987 and 1997. HIV-infected people are worried that doctors sometimes disrespect confidentiality. Confidentiality was found to be a basic prerequisite for building trusting relationships between an HIV-infected individual and a doctor within the counseling pro…

AdultMalemedicine.medical_specialtyCoping (psychology)Health (social science)Self DisclosureSocial PsychologyAdolescentSocial ValuesAttitude of Health PersonnelCultureDeveloping countryHIV InfectionsSocial value orientationsGrounded theoryPoliticsNursingAdaptation PsychologicalmedicineHumansConfidentialityAgedRetrospective StudiesPhysician-Patient Relationsbusiness.industryPublic healthPublic Health Environmental and Occupational HealthAIDS SerodiagnosisMiddle AgedLatviaFemaleContact TracingbusinessConfidentialityQualitative researchAIDS care
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Nurses' perceptions of the benefits and adverse effects of hand disinfection: alcohol-based hand rubs vs. hygienic handwashing: a multicentre questio…

2008

Summary Background  Nurses have a high risk of developing hand eczema due to hand disinfection procedures. Objectives  To investigate the perception of nurses regarding the adverse effects of hand washing (HW) and alcoholic disinfection (ADI), and to obtain data on the prevalence of hand dermatitis and sensitization to alcohols and alcohol-based hand rubs (ABHRs). Methods  A self-administered questionnaire survey, carried out as a pilot study (PS), followed by a modified multicentre study (MC) in five hospitals. Patch tests to ethanol (80%), 1-propanol (60%), 2-propanol (70%) and ABHRs were performed in a subsample. Results  The majority (PS 60·1%; MC 69·5%) of nurses considered ADI to be m…

AdultMalemedicine.medical_specialtyHand washingAttitude of Health Personnelmedia_common.quotation_subjectOccupational diseasePilot ProjectsDermatologyHand DermatosesNursing Staff HospitalDermatitis ContactAge DistributionHygieneInternal medicineGermanymedicineHumansSex DistributionAdverse effectmedia_commonEthanolbusiness.industryHygieneMiddle AgedPatch Testsmedicine.diseaseSurgeryDisinfectionTolerabilityDermatitis OccupationalHand eczemaIrritant contact dermatitisAnti-Infective Agents LocalFemalebusinessContact dermatitisHand DisinfectionThe British journal of dermatology
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Effect of overground vs treadmill running on plantar pressure: Influence of fatigue

2013

Abstract The differences produced when running on a treadmill vs overground may call into question the use and validity of the treadmill as a piece of equipment commonly used in research, training, and rehabilitation. The aim of the present study was to analyze under pre/post fatigue conditions the effect of treadmill vs overground on plantar pressures. Twenty-seven recreational runners (17 men and 10 women) ran on a treadmill and overground at two speeds: S 1  = 3.33 m/s and S 2  = 4.00 m/s, before and after a fatigue protocol consisting of a 30-min run at 85% of their individual maximal aerobic speed (MAS). Contact time (CT in seconds), peak pressure (PP in kPa), and relative load (RL in …

AdultMalemedicine.medical_specialtyHeelContact timeBiophysicsSTRIDEPhysical exerciseRunningTreadmill runningPressuremedicineHumansOrthopedics and Sports MedicineTreadmillFatigueFootbusiness.industryPlantar pressureRehabilitationRepeated measures designBiomechanical PhenomenaMetatarsusmedicine.anatomical_structurePhysical therapyFemaleHeelbusinessGait & Posture
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Helicobacter pylori infection in Burkina Faso: an enigma within an enigma.

2004

Background. In Burkina Faso, in contrast with high rates of Helicobacter pylori infection from an early age, the prevalence of H. pylori-associated diseases (ulcer and gastric cancer) is low. Aims. To look for the prevalence of H. pylori in healthy natives of Burkina Faso, both children and adults. Methods. We studied the prevalence of H. pylori infection in 258 healthy natives of Burkina Faso (70 children aged 6 months–15 years and 188 adults aged 16–65 years), using a serological screening (IgA and IgG H. pylori antibodies). All the studied subjects underwent a questionnaire regarding their life-style, socio-economic status, dietary habits and hygienic sanitary conditions. Data concerning…

AdultMalemedicine.medical_specialtyHelicobacter pylori infectionAdolescentAdult populationSerologyHelicobacter InfectionsSeroepidemiologic StudiesInternal medicineparasitic diseasesBurkina FasomedicinePrevalenceHumansChildClose contactAgedHigh rateHepatologybusiness.industryGastroenterologyAge FactorsInfantMiddle AgedImmunoglobulin ACross-Sectional StudiesChild PreschoolImmunoglobulin GImmunologyFemalebusinessDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Corneal Biomechanical Parameters With Corneoscleral Contact Lenses in Post-Laser In Situ Keratomileusis Eyes

2018

Objective: To evaluate corneal biomechanical parameters wearing corneoscleral contact lenses (CScL) in patients with irregular corneas after laser in situ keratomileusis (LASIK). Methods: Data from patients fitted with CScL because of corneal surface irregularities after complicated LASIK surgery were selected by two eye clinics. Previously and after 1 year of CScL fitting, corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc), and central corneal thickness were evaluated. In addition, visual acuity, subjective comfort, and wearing time CScL were reported. Results: The study comprised 27 eyes. Statistically significant differences were fo…

AdultMalemedicine.medical_specialtyIntraocular pressureCorneal Wavefront AberrationVisual acuitygenetic structuresmedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityCorneal resistance factorKeratomileusisLASIKCorneaCorneal hysteresis03 medical and health sciences0302 clinical medicineOphthalmologyMyopiamedicineHumansIn patientCorneal surfaceRefractive surgeryIntraocular PressureRetrospective Studiesbusiness.industryLASIKCorneal hysteresisContact Lenses Hydrophiliceye diseasesBiomechanical PhenomenaScleraOphthalmologymedicine.anatomical_structureCorneoscleral contact lensesPatient Satisfaction030221 ophthalmology & optometryFemalesense organsmedicine.symptombusinessSclera030217 neurology & neurosurgery
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A 12-month Prospective Study of Tear Osmolarity in Contact Lens Wearers Refitted with Daily Disposable Soft Contact Lenses

2020

SIGNIFICANCE Tear osmolarity has been reported as one of the best diagnostic tests for dry eye disease and its management. Contact lens wear is thought to influence tear homeostasis. Understanding how regular wear of contact lenses and their type affect tear osmolarity is important. PURPOSE The purpose of this study was to assess changes in tear osmolarity and ocular symptoms over a period of 12 months following refitting contact lens wearers with daily disposable contact lenses. METHODS Fifty subjects aged (mean ± SD) 26 ± 4 years were refitted with either silicone-hydrogel (delefilcon A, SiHy, n = 34) or hydrogel (omafilcon A, Hy, n = 16) daily disposable soft contact lenses. Study includ…

AdultMalemedicine.medical_specialtyLower scorelaw.inventionYoung Adult03 medical and health sciences0302 clinical medicinelawProsthesis FittingSurveys and QuestionnairesOphthalmologymedicineHumansOcular Surface Disease IndexProspective StudiesDisposable EquipmentProspective cohort studybusiness.industryOsmolar ConcentrationHydrogelsContact Lenses HydrophilicTear osmolarityeye diseasesLens (optics)Contact lensOphthalmologyTearsTime course030221 ophthalmology & optometryDry Eye SyndromesFemaleDaily disposablesense organsbusiness030217 neurology & neurosurgeryOptometryOptometry and Vision Science
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