Search results for "CONTINUA"
showing 10 items of 362 documents
Clinical and economic consequences of switching from omalizumab to mepolizumab in uncontrolled severe eosinophilic asthma
2021
AbstractSevere asthma is burdened by frequent exacerbations and use of oral corticosteroids (OCS), which worsen patients’ health and increase healthcare spending. The aim of this study was to assess the clinical and economic impact of switching from omalizumab (OMA) to mepolizumab (MEP) in patients eligible for both biologics, but not optimally controlled by omalizumab. We retrospectively enrolled uncontrolled severe asthmatic patients who switched from OMA to MEP during the last two years. Information included blood eosinophil count, asthma control test (ACT), spirometry, serum IgE, fractional exhaled nitric oxide (FeNO), OCS intake, drugs, exacerbations/hospitalizations, visits and diagno…
Newton algorithm for Hamiltonian characterization in quantum control
2014
We propose a Newton algorithm to characterize the Hamiltonian of a quantum system interacting with a given laser field. The algorithm is based on the assumption that the evolution operator of the system is perfectly known at a fixed time. The computational scheme uses the Crank-Nicholson approximation to explicitly determine the derivatives of the propagator with respect to the Hamiltonians of the system. In order to globalize this algorithm, we use a continuation method that improves its convergence properties. This technique is applied to a two-level quantum system and to a molecular one with a double-well potential. The numerical tests show that accurate estimates of the unknown paramete…
Enhancing organisational commitment through task significance: the moderating role of openness to experience
2020
International audience; Researchers have extensively explored the factors influencing employees’ organisational commitment. However, few studies make an explicit distinction between different commitment types when exploring its determinants, and the scholarly attention to individual differences is also limited. In this paper, we confirm that developing managerial interventions to enhance task significance can be useful to promote organisational commitment, but this relationship is contingent on the commitment type and the employees’ openness to experience. We focus on two forms of organisational commitment: affective and continuance commitment. Our study shows that task significance is a be…
Neuromodulation of chronic headaches: position statement from the European Headache Federation
2013
The medical treatment of patients with chronic primary headache syndromes (chronic migraine, chronic tension-type headache, chronic cluster headache, hemicrania continua) is challenging as serious side effects frequently complicate the course of medical treatment and some patients may be even medically intractable. When a definitive lack of responsiveness to conservative treatments is ascertained and medication overuse headache is excluded, neuromodulation options can be considered in selected cases.Here, the various invasive and non-invasive approaches, such as hypothalamic deep brain stimulation, occipital nerve stimulation, stimulation of sphenopalatine ganglion, cervical spinal cord sti…
Abitare nel reale. Dalla crisi della periferia alla tessitura di nuove relazioni contestuali
2019
I progetti redatti per “Palermo Sud-Est” sono il risultato di un Laboratorio di Laurea strutturatosi attraverso incontri, seminari, comunicazioni specialistiche, esposizioni critiche, che – in una strategia condivisa – ha visto ogni studente elaborare il proprio lavoro nel confronto con gli altri attori del Laboratorio stesso. La ricerca sui “progetti urbani” è stata impostata di modo che ogni laureando fosse messo a conoscenza dei progetti svolti nello stesso ambito territoriale dai colleghi che l’avevano preceduto, così da poter operare in continuità e contribuire a formulare un ragionamento unitario, nel quale ogni progetto costituisse continuazione, verifica o anche variante dei precede…
Chronic paroxysmal hemicrania and hemicrania continua responding to topiramate: Two case reports
2007
Chronic paroxysmal hemicrania (CPH) is a rare primary headache syndrome, which is classified along with cluster headache and short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing as a trigeminal autonomic cephalalgia (TACs). Hemicrania continua (HC) was previously classified as one of the TACs, but in the recent second classification of the International Headache Society this disorder was moved to the group of other primary headaches. Both CPH and HC are characterised by moderate to excruciating pain requiring pharmacological treatment; furthermore, both conditions are characterised by an absolute response to indomethacin, which represents one of the…
Topiramate and Metabolic Acidosis in Infants and Toddlers
2002
Summary: Purpose: Topiramate (TPM) inhibits carbonic anhydrase, with metabolic acidosis as a possible side effect, although this has been reported in only two adult cases. We investigated the acid–base metabolism in infants and toddlers treated with TPM. Methods: Nine infants and toddlers aged 5 months to 2.3 years (median, 6 months) were treated with TPM at maximal doses of 8.2–26 mg/kg/day (median, 11 mg/kg/day). The maximal TPM dose was achieved after 8–35 days (median, 17 days). TPM was given in addition to other antiepileptic drugs (AEDs) in five cases and as a sole AED in four patients with refractory epilepsy resistant to multiple AEDs. The diagnoses were infantile spasms (n = 5), e…
La Comedia llamada Thebayda
2021
Edición crítica de la Comedia Thebayda (anónimo valenciano de 1521). Comedia que forma parte de la tradición de comedias humanísticas españolas en lengua vulgar. Obra dedicada al Duque de Gandía D. Juan de Borja y Enríquez.
La Égloga de la Tragicomedia de Calisto y Melibea (1513)
2003
La Égloga de la tragicomedia de Calisto y Melibea, compuesta por Pedro Manuel Ximénez de Urrea, y publicada en su Cancionero (Logroño, Arnau de Brocar, 1513), versifica un tercio del 1º Acto de La Celestina, mediante 89 coplas mixtas de nueve versos (rima abba:ccddc), más dos redondillas, una quintilla y una cuarteta, aparte del villancico final. Este texto es la primera imitación de La Celestina en lengua castellana
Imágenes sobre Chile : dos miradas para construir la memoria
2019
Resumen: Este artículo presenta un material pedagógico que, a través del cine, permite desarrollar contenidos incluidos en los programas de estudio del curriculum escolar chileno. Se trata de la obra de los cineastas Raúl Ruiz y Patricio Guzmán que, desde miradas muy diversas nos permiten acercarnos a un mismo país, antes y después de la dictadura militar. Estos materiales integran la colección editorial Educación Artística realizada por el Ministerio de las Culturas, las Artes y el Patrimonio, de Chile.
 
 Palabras clave: Educación artística, cine, formación ciudadana, memoria, didáctica.
 
 Abstract: This paper presents a pedagogic material that trough cinema allows …