Search results for "COU"

showing 10 items of 14566 documents

Sound-Induced Flash Illusions Support Cortex Hyperexcitability in Fibromyalgia

2022

Objectives. Fibromyalgia (FM) is characterized by spontaneous chronic widespread pain in combination with hyperalgesia to pressure stimuli. Sound-induced flash illusions (SIFIs) reflect cross-modal interactions between senses allowing to assess a visual cortical hoerexcitability (VCH) by evaluating the fission and fusion illusions disruption. The aims of the present study were to explore whether SIFIs are perceived differently in patients with fibromyalgia as compared to healthy controls (HCs) and how migraine affects fission and fusion illusions in fibromyalgia. Methods. A single flash (F) accompanied by 0 to 4 beeps (B) was presented to induce the fission illusion while multiple flash (i.…

AdultFibromyalgiaArticle SubjectMigraine DisordersInfant NewbornAnxietyMiddle AgedIllusionsAnesthesiology and Pain MedicineNeurologyIllusionMigraine DisorderAcoustic StimulationAuditory PerceptionHumansSettore MED/26 - NeurologiaFemalePhotic StimulationHumanPain Research and Management
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Molecular characterization of 39 de novo sSMC: contribution to prognosis and genetic counselling, a prospective study.

2012

Small supernumerary marker chromosomes (sSMCs) are structurally abnormal chromosomes that cannot be characterized by karyotype. In many prenatal cases of de novo sSMC, the outcome of pregnancy is difficult to predict because the euchromatin content is unclear. This study aimed to determine the presence or absence of euchromatin material of 39 de novo prenatally ascertained sSMC by array-comparative genomic hybridization (array-CGH) or single nucleotide polymorphism (SNP) array. Cases were prospectively ascertained from the study of 65,000 prenatal samples [0.060%; 95% confidence interval (CI), 0.042-0.082]. Array-CGH showed that 22 markers were derived from non-acrocentric markers (56.4%) a…

AdultGenetic MarkersRiskEuchromatinKaryotypeContext (language use)Prenatal diagnosisSingle-nucleotide polymorphismGenetic CounselingBiologyPolymorphism Single NucleotideYoung AdultPregnancyPrenatal DiagnosisGeneticsmedicineSNPHumansGenetic Predisposition to DiseaseProspective StudiesGenetics (clinical)Genetic Association StudiesIn Situ Hybridization FluorescenceGeneticsChromosome AberrationsComparative Genomic Hybridizationmedicine.diagnostic_testKaryotypeMiddle AgedPrognosisMolecular biologyFemaleFranceSwitzerlandSNP arrayFluorescence in situ hybridizationGenome-Wide Association StudyClinical genetics
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Clinical usefulness of Glycated Albumin in the diagnosis of diabetes: Results from an Italian study

2018

Objectives: Glycated Albumin (GA) has been proposed as a screening marker for diabetes in Asian countries in the last years. Nevertheless, few studies have been conducted in Caucasian population. The aim of this study is to evaluate the clinical usefulness of GA in diabetes diagnosis in Caucasian asymptomatic subjects considered at risk of diabetes based on medical history and Fasting Plasma Glucose (FPG). Design and methods: Three hundred and thirty-four Caucasian subjects having one or more risk factor for diabetes, and/or FPG ranging from 5.6 mmol/L to 6.9 mmol/L with no symptoms for diabetes were enrolled in this study. Plasma GA was measured by an enzymatic method (quantILab Glycated A…

AdultGlycation End Products AdvancedMalemedicine.medical_specialtyHbA1cClinical Biochemistry030209 endocrinology & metabolism030204 cardiovascular system & hematologyDiabeteAsymptomatic03 medical and health sciences0302 clinical medicineGlycated albuminGlycated albuminDiabetes mellitusInternal medicineDiabetes MellitusmedicineAsian countryHumansGlycated Serum AlbuminMedical historyRisk factorCaucasian populationSerum AlbuminDiabetes; Glycated albumin; HbA1c; Impaired fasting glucose; ROC curve; Screening; Clinical BiochemistryAgedGlycated Hemoglobinbusiness.industryDiabetesGeneral MedicineMiddle AgedImpaired fasting glucosemedicine.diseaseImpaired fasting glucoseROC curveItalyScreeningFemalemedicine.symptombusiness
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Liver Perfusate Natural Killer Cells from Deceased Brain Donors and Association with Acute Cellular Rejection after Liver Transplantation: A Time-to-…

2019

Background The ability to predict which recipients will successfully complete their posttransplant clinical course, which is crucial for liver transplant (LT) programs. The assessment of natural killer (NK) cell subset determined by flow cytometry from a monocentric series of consecutive liver perfusates could help identify risk factors portending adverse LT outcomes. Methods Liver perfusates were collected during the back-table surgical time after the procurement procedures for donors after brain death. Lymphocytic concentrations and phenotypes were matched with donors after brain death characteristics and indications, timing, surgical techniques, outcomes, and biopsy-proven acute cellular…

AdultGraft RejectionMaleTime FactorsAcute cellular rejectionmedicine.medical_treatment030230 surgeryLiver transplantationFlow cytometry03 medical and health sciences0302 clinical medicineMedicineHumansKiller CellsLiver immunologyAgedTransplantationmedicine.diagnostic_testbusiness.industryClinical courseMiddle AgedTissue DonorsLiver TransplantationKiller Cells NaturalLiverT cell subsetImmunologyAcute DiseaseNaturalAcute Disease Adult Aged Female Graft Rejection Humans Killer Cells Natural Liver Liver Transplantation Male Middle Aged Time Factors Tissue Donors030211 gastroenterology & hepatologyFemalebusiness
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Treatment of acute rejection of cadaveric renal allografts with rabbit antithymocyte globulin.

1982

In a prospective randomized single-blind trial, we compared the effectiveness of rabbit antithymocyte globulin (RATG) in the treatment of acute renal graft rejection with the results of treatment by high oral doses of prednisone. Twenty recipients of cadaveric kidneys were included in each group. In the RATG group, the prednisone dose was not increased and a dose-by-rosette protocol was used to keep T cell levels between 50 and 150/mm3. In this group 15 of the 20 patients responded to the treatment. One of these patients lost her kidney afterward because of a technical failure. In five patients rejection was irreversible despite a subsequent course of high-dose prednisone orally. In the pre…

AdultGraft RejectionMaleTransplantationmedicine.medical_specialtyTime FactorsDose-Response Relationship Drugbusiness.industryT-LymphocytesRenal graftKidney TransplantationSurgeryRabbit antithymocyte globulinLeukocyte CountPrednisoneMedicineHumansPrednisoneFemaleProspective StudiesbusinessCadaveric spasmmedicine.drugAntilymphocyte SerumTransplantation
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Detection of sound rise time by adults with dyslexia

2005

Low sensitivity to amplitude modulated (AM) sounds is reported to be associated with dyslexia. An important aspect of amplitude modulation cycles are the rise and fall times within the sound. In this study, simplified stimuli equivalent to just one cycle were used and sensitivity to varying rise times was explored. Adult participants with dyslexia or compensated dyslexia and a control group performed a detection task with sound pairs of different rise times. Results showed that the participants with dyslexia differed from the control group in rise time detection and a correlation was found between rise time detection and reading and phonological skills. A subgroup of participants with lower…

AdultHandwritingLinguistics and Languagemedicine.medical_specialtyLoudness PerceptionCognitive Neurosciencemedia_common.quotation_subjectExperimental and Cognitive PsychologyAudiologybehavioral disciplines and activitiesLanguage and LinguisticsDevelopmental psychologyPhonemic contrastDyslexiaSpeech and HearingPhoneticsCommunication disorderReading (process)PerceptionReaction TimemedicineHumansLanguage disordermedia_commonDyslexiaCognitionmedicine.diseaseAcoustic StimulationPattern Recognition VisualReadingRise timePsychologyBrain and Language
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Risk factors for unwanted pregnancy and subsequent abortion among women aged 16 to 25 years in Latvia

2015

Objective To investigate the risk factors associated with unwanted pregnancy in 16- to 25-year-old women in Latvia. Methods Case-control study of 16- to 25-year-old, sexually active women who did not want to get pregnant: the cases were 144 women who underwent their fi rst abortion whereas 278 nulliparous women served as controls. Data concerning them were obtained by using a semi-structured anonymous questionnaire that included questions about education, sexual life habits, contraceptive practice and a multiple-choice test to assess knowledge about contraception. Results Women who underwent an abortion had had more lifetime sexual partners, had more often not used any contraception, and we…

AdultHealth Knowledge Attitudes Practicemedicine.medical_specialtyAdolescentSexual Behaviormedia_common.quotation_subjectPopulationDeveloping countryFertilityAbortionHealth Services AccessibilityYoung AdultPregnancyRisk FactorsHumansMedicinePharmacology (medical)Young adulteducationContraception BehaviorReproductive healthmedia_commonGynecologyeducation.field_of_studybusiness.industryCase-control studyObstetrics and GynecologyAbortion InducedLatviaPregnancy UnwantedContraceptionSexual PartnersReproductive MedicineFamily planningFemalebusinessDemographyThe European Journal of Contraception & Reproductive Health Care
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Conservative vs. Surgical Management of Post-Traumatic Epidural Hematoma: A Case and Review of Literature

2015

Patient: Male, 30 Final Diagnosis: Acute epidural hematoma Symptoms: — Medication: — Clinical Procedure: Observation Specialty: Neurosurgery Objective: Unusual clinical course Background: Trauma is the leading cause of death in people younger than 45 years and head injury is the main cause of trauma mortality. Although epidural hematomas are relatively uncommon (less than 1% of all patients with head injuries and fewer than 10% of those who are comatose), they should always be considered in evaluation of a serious head injury. Patients with epidural hematomas who meet surgical criteria and receive prompt surgical intervention can have an excellent prognosis, presumably owing to limited unde…

AdultHematoma Epidural CranialMalemedicine.medical_specialtyDecision MakingSpecialtyNeurosurgical ProceduresHematomaEpidural hematomaImaging Three-DimensionalX ray computedmedicineCerebral Hemorrhage TraumaticHematoma Subdural AcuteCraniocerebral TraumaHumansbusiness.industryClinical courseDisease ManagementGeneral MedicineArticlesmedicine.diseaseCraniocerebral traumaSurgeryTomography x ray computedBrain InjuriesNeurosurgerybusinessTomography X-Ray ComputedThe American Journal of Case Reports
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Cultural and communicational traits of oral health care: results of a Finnish case study.

2006

This paper aims to describe the cultural and communicational traits of Finnish oral health care. First, employees' views and experiences regarding their organization and their position within it are investigated and, second, relations between different individual and organizational factors are analyzed. Finally, a conceptual framework of organizational coherence is constructed.The paper shows that data collection (n = 58, 84 percent response rate) was carried out in 2002 at a Finnish dental clinic by using a semi-structured questionnaire. The data were analyzed statistically by using, among other things, non-parametric tests and a structural equation model (LISREL) and qualitatively by usin…

AdultHierarchy SocialDental AssistantsStructural equation modelingLISRELJob SatisfactionHealth servicesProfessional RoleMedicineDental StaffHumansFinlandResponse rate (survey)Data collectionbusiness.industryHealth PolicyCommunicationDental ClinicsProcess Assessment Health CareMiddle AgedOrganizational CultureBenchmarkingLeadershipDental clinicConceptual frameworkState DentistryOrganizational Case StudiesBusiness Management and Accounting (miscellaneous)Oral health carebusinessSocial psychologyInstitutional PracticeJournal of health organization and management
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The impact of the 2008 economic crisis on the increasing number of young psychiatric inpatients.

2017

Abstract Background Little is published about the impact of the 2008 economic crisis on mental health services in Spain. Method An interrupted time series analysis was conducted to investigate a potential short-term association between the 2008 economic crisis and the number of psychiatric hospital admissions. The timing of the intervention (April 2008) was based on observed changes in Gross Domestic Product (GDP). Data on 1,152,880 psychiatric inpatients from the national Hospital Morbidity Survey, 69 months before and after the onset of the economic crisis (April 2008), were analyzed. Results Age-adjusted psychiatric (ICD9 290–319) hospital discharge rates significantly increased from Apr…

AdultHospitals PsychiatricMalemedicine.medical_specialtyAdolescentmedia_common.quotation_subjectGross domestic product03 medical and health sciencesYoung Adult0302 clinical medicinePatient AdmissionRisk FactorsIntervention (counseling)medicinePsychiatric hospitalHumans030212 general & internal medicinePsychiatryChildDepression (differential diagnoses)media_commonAgedAged 80 and overbusiness.industryMental DisordersAge FactorsGeneral MedicineMiddle Agedmedicine.diseaseNeuroticismMental healthPersonality disorders030227 psychiatryEconomic RecessionSpainUnemploymentChild PreschoolUnemploymentFemalebusiness
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