Search results for "CQ"
showing 10 items of 1801 documents
Strategies for structure solution and refinement of small organic molecules from electron diffraction data and limitations of the simulation approach
1999
In recent years, a series of non-linear optically active bis(benzylidene) ketones have been synthesized and investigated by electron crystallography. In most cases, structure refinement was possible by combining electron diffraction analysis and quantum-mechanical calculations with maximum-entropy methods. However, when the torsional angles between the phenyl rings and the C=C double bonds are strongly affected by the crystal field, this method fails because packing-energy calculations are not sufficiently sensitive. This problem can be solved by refining the approximate model with SHELXL, if the data set is sufficiently accurate and the model close to the correct structure. Here it is show…
Differentiation in language and gesture use during early bilingual development of hearing children of Deaf parents
2014
Hearing children of Deaf parents simultaneously acquire sign language and spoken language, which have many structural differences and represent two different modalities. We video-recorded eight children every six months between the ages of 12 and 24 months during three different play sessions: with their Deaf parent, with the Deaf parent and a hearing adult, and with a hearing adult alone. Additionally, we collected data on their vocabulary development in both sign language and spoken language. Children as young as 12 months old accommodated their language use according to the language(s) of their interlocutor(s). Additionally, the children used a manual modality that included gestures more…
TRANSACTIONAL SEX, EARLY MARRIAGE, AND PARENT– CHILD RELATIONS IN A TANZANIAN SLUM
2016
Transactional sex has been recognized as a major factor in the persistence of HIV/AIDS in Sub-Saharan Africa, yet it also has implications for the persistence of poverty. Using interview data collected between 2010 and 2015, this article examines how Muslim families in Dar es Salaam are affected by transactional sexual behavior.1 Examined are motives for transactional sex, how poor families view the purpose of marriage, and religious teachings and cultural beliefs about the onset of adulthood. Familial strategies to ensure provision for daughters and to improve the family’s socio-economic situation are impeded by the fact that in a context of high unemploy ment, transactional sex of ten rep…
La culture en campagne : de l'atonie à la mobilisation antifasciste. Politique culturelle et débat public en France lors des élections de 2002
2004
International audience; Cet article part de l'absence de débat sur la politique culturelle au cours de la campagne électorale des élections présidentielles et législatives du printemps 2002. Il montre les ressorts de cette atonie, avant d'expliquer le réflexe anti-fasciste qui marque les semaines qui suivent le premier tour des présidentielles et la présence de Jean-Marie Le Pen au second tour. L'analyse de la défaite du candidat socialiste est aussi un moment de remise en cause du modèle français de politique culturelle. Le débat s'estompe vite et ne débouche pas sur la mise en place d'une politique culturelle 'refondée'.
Marta Dillon y Joaquín Hurtado : crónicas de la enfermedad crónica. / Marta Dillon and Joaquín Hurtado: chronicles of a chronic disease
2017
Resumen: A través de la lectura de las crónicas sobre el VIH/sida de Marta Dillon y Joaquín Hurtado, analizo cómo estos autores narran la convivencia crónica con el VIH que les impone el aprendizaje de nuevas formas de gestionar la vida y de autorrepresentarse. Estudio las crónicas no solo como estrategias terapéuticas para lidiar con los profundos cambios corporales y emocionales que trae consigo el diagnóstico, sino también como estrategias políticas para incidir en la normalización y percepción social de la enfermedad como entidad crónica. La reescritura del cuerpo, consustancial al devenir crónico de la enfermedad, enfrenta a los autores a cuestionar la improductividad o incapacidad de …
El model de la sida i les seves víctimes / The AIDS model and its victims
2017
Resumen: En un moviment similar al que efectua Michel Foucault en analitzar la lepra i la pesta com a malalties model del poder disciplinari i del poder sobirà, l’objectiu serà presentar la sida com a malaltia model del biopoder. Es tracta d’analitzar com els mecanismes de poder i de saber que gestionen la sida responen a una determinada economia de poder, que ja no pot ser explicada a través del model binari de la lepra, ni del model pesat i geomètric de la pesta. Per aconseguir això, farem un breu recorregut pel concepte de biopoder i pel model de la lepra i de la pesta. Seguidament, presentarem les novetats del model de la sida. L’anàlisi es centrarà en els primers anys de la malaltia: f…
Facework and Prosocial Teasing in a Synchronous Video Communication Exchange
2019
This study centres on the analysis of prosocial teasing during a videoconference (telecollaboration) exchange between mixed-gender adolescent secondary school students from Spain and Germany. We contend that the provocative elements present in prosocial teasing activate a play frame, in Gregory Bateson’s terms, in which seemingly hostile face acts can be interpreted as playful behaviour. We argue that successful teasing can ultimately enhance the face of the teaser and that of the person being teased and thus build up rapport between them. Our analysis of the facework in the interaction during this telecollaboration exchange is based on Erwin Goffman’s notions of face, demeanour and deferen…
Designing Dissensual Common Sense: Critical Art, Architecture, and Design in Jacques Rancière’s Political Thought
2021
How can design be socially engaged and politically efficient, as proposed by discourses labeled as critical design? This article introduces a conceptualization and historiography of politically charged design discourse based on philosopher Jacques Rancière’s work on the intersections of politics, aesthetics, and critical artistic practices. By focusing especially on Rancière’s reading of the genealogy of design from Ruskin to constructivism and the Bauhaus, the article aims to show that there is an important connection between design and politics present in Rancière’s thought. Rather than solely revealing the oppressive dimension embedded in designed forms, for Rancière, design is itself a …
Activation of the human immune system via toll-like receptors by the oncolytic parvovirus H-1.
2012
This study aimed to investigate the function of toll-like receptors (TLRs) during oncolytic parvovirus H-1 (H-1PV)-induced human immune responses. First, the role of TLRs in the activation of the NFκB transcription factor was characterized; second, the immunologic effects of H-1PV-induced tumor cell lysates (TCL) on human antitumor immune responses were evaluated. A human ex vivo model was used to study immune responses with dendritic cells (DCs). Human embryonic kidney cells (HEK293) transfected to stably express TLRs were used as potential human DC equivalents to further investigate the role of specific TLRs during immune activation. TLR3 and TLR9 were activated by H-1PV infection, which …
Impaired Mast Cell-Driven Immune Responses in Mice Lacking the Transcription Factor NFATc2
2009
Abstract The three calcium-dependent factors NFATc1, c2, and c3 are expressed in cells of the immune system and play pivotal roles in modulating cellular activation. With regard to NFATc2, it was reported that NFATc2-deficient mice display increased immune responses in several models for infection and allergy in vivo. This led to the assumption that NFATc2 is involved in the maintenance of immune homeostasis. Using the synthetic TLR7 agonist imiquimod as an adjuvant in epicutaneous peptide immunization, we observed that both the inflammatory reaction and the peptide-specific CTL response are severely impaired in NFATc2-deficient mice. Detailed analyses revealed that early production of proi…