Search results for "CQ"

Thromboinflammation and Vascular Dysfunction.

2018

Thromboinflammation and vascular dysfunction are inseparably combined with the innate and the adaptive immune response. While the role of this interplay has gained considerable attention in the arena of atherosclerosis/atherothrombosis and in deep vein thrombosis, its role in other forms of vascular disease and risk factors is currently emerging. In this brief review, we will focus on thromboinflammation with regard to cytokine signalling as well as on the novel role of a vascular coagulation-inflammatory circuit in arterial hypertension.Thrombo-Inflammation und vaskuläre Dysfunktion sind untrennbar mit dem angeborenen und dem erworbenen Immunsystem verbunden. Dieses Zusammenspiel wurde im …

El descrédito de la democracia / 3: La corrupción blanca

2006

Cosa significa "democrazia" nell'era di internet?

2022

Le società democratiche stanno vivendo oggi una fase di grande trasformazione a causa anche dei grandi progressi dovuti alla tecnologie digitali. Di fronte alle difficoltà legate al fenomeno dell'individualismo bisogna evitare entrambi gli estremi: quello di chi demonizza la tecnica e i fenomeni di modernizzazione e quelli di chi guarda ai nuovi strumenti con un fideismo acritico. Le intuzioni di Tocqueville possano ancora oggi aiutarci ad avere un atteggiamento critico equilibrato tra questi due estremi.

Performatiivisuus Jacques Derridan filosofisessa kirjoituksessa

2014

TIIVISTELMÄ DIFFÉRANCEN TEKO Performatiivisuus Jacques Derridan filosofisessa kirjoituksessa Mari Laaksonen Filosofia pro gradu-tutkielma Yhteiskuntatieteellinen laitos Jyväskylän yliopisto Ohjaajat: Olli-Pekka Moisio ja Jussi Backman Syyslukukausi 2014 59 sivua Tässä tutkielmassa sovellan J.L. Austinin performatiivisuuden käsitettä ranskalaisfilosofi Jacques Derridan muotoileman différancen käsitteen analyysiin fonosentrismin kritiikin sekä strategisen kirjoituksen konteksteissa. Performatiivin käsitteen tausta on J.L. Austin tekemässä erottelussa performatiivisten ja konstatiivisten lausumien välille. Konstatiivit viittaavat lausumiin, jotka kuvailevat jotakin asiantilaa. Performatiiviset…

Conceptual design of the TRACE detector readout using a compact, dead time-less analog memory ASIC

2015

[EN] The new TRacking Array for light Charged particle Ejectiles (TRACE) detector system requires monitorization and sampling of all pulses in a large number of channels with very strict space and power consumption restrictions for the front-end electronics and cabling. Its readout system is to be based on analog memory ASICs with 64 channels each that sample a View the MathML source window of the waveform of any valid pulses at 200 MHz while discarding any other signals and are read out at 50 MHz with external ADC digitization. For this purpose, a new, compact analog memory architecture is described that allows pulse capture with zero dead time in any channel while vastly reducing the tota…

Echinoderm Antimicrobial Peptides

2016

Abstract Antimicrobial peptides (AMPs) are widely expressed in organisms and have been linked to innate and acquired immunity in vertebrates. These compounds are constitutively expressed from different cellular types to interact directly with infectious agents and/or modulate immunoreactions. In invertebrates, including echinoderms, which lack a vertebrate-type adaptive immune system, AMPs represent the major humoral defense system against infection, showing a diverse spectrum of action mechanisms, most of them related to plasma membrane disturbance and lethal alteration of microbial integrity. Here, we summarize the knowledge of AMPs in echinoderms as Strongylocins identified in the sea ur…

Liver fibrosis: Common mechanisms and antifibrotic therapies

2015

Liver fibrosis and in particular cirrhosis have become major endpoints in clinical trials of patients with chronic liver diseases. Here, viral hepatitis, alcoholic and non-alcoholic steatohepatitis have become the major etiologies. We have made great progress in our understanding of the mechanisms and the cell biology of liver fibrosis and have already made the transition from preclinical testing of antifibrotic agents and strategies towards clinical translation. There continues to be an urgent need for specific antifibrotic therapies, despite the advent of highly potent antiviral agents that can even induce regression of advanced fibrosis. This review addresses central mechanisms and cells…

Multispectral integral imaging acquisition and processing using a monochrome camera and a liquid crystal tunable filter

2012

This paper presents an acquisition system and a procedure to capture 3D scenes in different spectral bands. The acquisition system is formed by a monochrome camera, and a Liquid Crystal Tunable Filter (LCTF) that allows to acquire images at different spectral bands in the [480, 680]nm wavelength interval. The Synthetic Aperture Integral Imaging acquisition technique is used to obtain the elemental images for each wavelength. These elemental images are used to computationally obtain the reconstruction planes of the 3D scene at different depth planes. The 3D profile of the acquired scene is also obtained using a minimization of the variance of the contribution of the elemental images at each …

Homotypic Protection Against Rotavirus-Induced Diarrhea in Infant Mice Breast-Fed by Dams Immunized with the Recombinant VP8* Subunit of the VP4 Caps…

2000

The outer capsid proteins VP4 and VP7 induce neutralizing antibody against rotavirus. We have investigated in a mouse model the protection mediated by immunization with VP8*, the amino-terminal tryptic fragment of VP4. BALB/c female mice immunized with simian rotavirus SA11 VP6 and VP8* proteins expressed in Escherichia coli were mated with seronegative males. Litters were orally challenged with the SA11 strain (P5B[2], G3) or with the murine rotavirus strain EDIM (P10[16], G3) to verify the degree of protection against diarrhea induced in the newborns. Only those pups born to dams immunized with VP8* did not develop diarrhea after having been orally challenged with the SA11 strain. Pups bo…

Induction of tcI 7 , a gene encoding a β-subunit of proteasome, in tobacco plants treated with elicitins, salicylic acid or hydrogen peroxide 1

2000

We previously isolated, by differential display and 5′ RACE (rapid amplification of cDNA ends), cDNAs corresponding to genes activated following cryptogein treatment of tobacco cell suspensions, among them tcI 7 (tcI for obacco ryptogein nduced), a gene encoding a β-subunit of proteasome. Here, we report that tcI 7 was up-regulated in tobacco plants treated with elicitins (cryptogein and parasiticein) that have been shown to induce a systemic acquired resistance (SAR). Moreover, subsequent inoculation of tobacco with the pathogen Phytophthora parasitica var. nicotianae (Ppn) was shown to induce an additional activation of tcI 7 in tobacco plants pretreated with cryptogein. We also showed an…