Search results for "CQ"

The electronion scattering experiment ELISe at the International Facility for Antiproton and Ion Research (FAIR) - A conceptual design study

2011

The electronion scattering experiment ELISe is part of the installations envisaged at the new experimental storage ring at the International Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany. It offers an unique opportunity to use electrons as probe in investigations of the structure of exotic nuclei. The conceptual design and the scientific challenges of ELISe are presented. © 2011 Elsevier B.V. All rights reserved.

Upgrade of ATLAS hadronic Tile Calorimeter for the High-Luminosity LHC

2022

The Tile Calorimeter (TileCal) is a sampling hadronic calorimeter covering the central region of the ATLAS experiment, with steel as absorber and plastic scintillators as active medium. The High-Luminosity phase of LHC, delivering five times the LHC nominal instantaneous luminosity, is expected to begin in 2028. TileCal will require new electronics to meet the requirements of a 1 MHz trigger, higher ambient radiation, and to ensure better performance under high pile-up conditions. Both the on- and off-detector TileCal electronics will be replaced during the shutdown of 2026-2028. The TileCal upgrade program has included extensive R&D and test beam studies. A Demonstrator module with reverse…

IGISOL control system modernization

2016

Abstract Since 2010, the IGISOL research facility at the Accelerator laboratory of the University of Jyvaskyla has gone through major changes. Comparing the new IGISOL4 facility to the former IGISOL3 setup, the size of the facility has more than doubled, the length of the ion transport line has grown to about 50 m with several measurement setups and extension capabilities, and the accelerated ions can be fed to the facility from two different cyclotrons. The facility has evolved to a system comprising hundreds of manual, pneumatic and electronic devices. These changes have prompted the need to modernize also the facility control system taking care of monitoring and transporting the ion beam…

Contributions and limitations of self assessment of competences by higher education graduates

2009

This work presents a continuum of competence. On one extreme of which there is a subtlety of concept of competence. On the other, there are rigorous econometric analyses to find the answer to a critical question: ―to what extent is the assessment of competence reliable? ‖ Quest into the etymology helped us providing a rationale in favour of the preferred use of competence over competency. Moreover, we come to trace its roots in French literature where it was in use long before its emergence in English literature. We found that competences were common among various geopolitical locations and inferred that interest in competence has been internationalised realistically. Both English and Frenc…

Genetic predisposition to male breast cancer in Poland

2021

Abstract Background Breast cancer in men accounts for fewer than 1 % of all breast cancer cases diagnosed in men and women. Genes which predispose to male breast cancer include BRCA1 and BRCA2. The role of other genes is less clear. In Poland, 20 founder mutations in BRCA1, BRCA2, CHEK2, PALB2, NBN, RECQL are responsible for the majority of hereditary breast cancer cases in women, but the utility this genes panel has not been tested in men. Methods We estimated the prevalence of 20 alleles in six genes (BRCA1, BRCA2, CHEK2, PALB2, NBN, RECQL) in 165 Polish male breast cancer patients. We compared the frequency of selected variants in male breast cancer cases and controls. Results One of the…

Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes

2020

Interferons are crucial for adaptive immunity and play an important role in the immune landscape of breast cancer. Using microarray-based gene expression analysis, we examined the subtype-specific prognostic significance of interferon-&gamma

Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of r…

2015

BackgroundAcquired resistance to BRAF inhibitors (BRAFi) is a near-universal phenomenon caused by numerous genetic and non-genetic alterations. In this study, we evaluated the spectrum, onset, pattern of progression, and subsequent clinical outcomes associated with specific mechanisms of resistance.MethodsWe compiled clinical and genetic data from 100 patients with 132 tissue samples obtained at progression on BRAFi therapy from 3 large, previously published studies of BRAFi resistance. These samples were subjected to whole-exome sequencing and/or polymerase chain reaction-based genetic testing.ResultsAmong 132 samples, putative resistance mechanisms were identified in 58%, including NRAS o…

Navigating high-choice European political information environments : a comparative analysis of news user profiles and political knowledge

2021

The transition from low- to high-choice media environments has had far-reaching implications for citizens’ media use and its relationship with political knowledge. However, there is still a lack of comparative research on how citizens combine the usage of different media and how that is related to political knowledge. To fill this void, we use a unique cross-national survey about the online and offline media use habits of more than 28,000 individuals in 17 European countries. Our aim is to (i) profile different types of news consumers and (ii) understand how each user profile is linked to political knowledge acquisition. Our results show that five user profiles – news minimalists, social m…

PROGETTAZIONE DI UNA OPERA DI PRESA A BASSO IMPATTO AMBIENTALE PER UN IMPIANTO MINI IDROELETTRICO IN SICILIA

2013

A innovative semi-immergible USV (SI-USV) drone for marine and lakes operations with instrumental telemetry and acoustic data acquisition capability

2015

The proposed project shows the results obtained in the implementation and testing in lacustrine and marine environment of a nautical remote controlled vehicle with surface navigation and innovative features Semi-Immersible (SI-USV). This vehicle is based on a pending patent belonging to Palermo University (Patent Pending RM2012A000209 and RM2012A000209) concerning innovative semi-immersible vehicles (SI-Drone), that can be remotely controlled from the ground, air, satellite and sea also during the semi-immersible operation. The vehicle with electric power is coupled with a jet propulsion, given the low draft, makes it possible to navigate in shallow waters or coastal shipping or sandbars. T…