Search results for "CREATINE"
showing 3 items of 213 documents
Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine C…
2021
Ophthalmic drug delivery is still a challenge due to the protective barriers of the eye. A common strategy to promote drug absorption is the use of ocular permeation enhancers, while an innovative approach is the use of polymeric micelles. In the present work, the two mentioned approaches were coupled by conjugating ocular permeation enhancers (PEG2000, carnitine, creatine, taurine) to an inulin-based co-polymer (INU-EDA-RA) in order to obtain self-assembling biopolymers with permeation enhancer properties for the hydrophobic drug dexamethasone (DEX). Inulin derivatives were properly synthetized, were found to expose about 2% mol/mol of enhancer molecules in the side chain, and resulted abl…
Gene expressions of SREBP-2, PPARδ, MYH7 and blood lipid changes induced by stretch-shortening cycle exercise
2011
The present study was to investigate whether the mRNA levels of the transcription factors, sterol regulatory element-binding protein-2 (SREBP-2), peroxisome proliferator-activated receptor-δ (PPARδ) as well as slow type myosin heavy chain (MYH7) gene are modulated after exhaustive exercise and if so, whether such alterations are related to the percentage of MHC isoforms. In particular, this study was undertaken to examine whether the level of selected blood parameters are influenced by fatiguing stretch-shortening cycle (SSC) exercise. Ten healthy men performed unilateral exhaustive repeated jumps on a special sledge. The maximal voluntary contraction (MVC) was examined before, immediately,…
The Effects of Cold Water Immersion on the Recovery of Drop Jump Performance and Mechanics : A Pilot Study in Under-20 Soccer Players
2020
Cold water immersion (CWI) is a popular method used for enhancing recovery from exercise. However, the efficacy of this approach is inconclusive and studies investigating variables contributing to overall performance are scarce. Additionally, few studies have investigated the recovery of stretch-shortening cycle (SSC) performance after a fatiguing SSC task. The SSC occurs naturally in human locomotion and induces a recovery pattern different from isolated muscle contractions (e.g., pure eccentric exercise). Therefore, the main aim of this study was to investigate the effects of a single CWI on jumping performance and mechanics after exhaustive SSC exercise. On a sledge apparatus, 10 male un…